The invention relates to a method of producing a pearl liquid, a pearl ginseng liquid and pearl powder easily absorbed by a human body by using pearl powder as a traditional Chinese medicinal material, which belongs to the technical field of production of the pearl liquid. The method comprises the following steps of firstly, preparing the pearl powder or pearl layer powder; secondly, dissolving with hydrochloric acid until the PH value reaches 6.4 to 6.6; thirdly, diluting, and filtering with filter paper to obtain conchiolin; fourthly, combining a plurality of parts of the conchiolin in the third step, and hydrolyzing the combined conchiolin with citric acid; fifthly, neutralizing until the PH value reaches 4.4 to 4.6 to obtain liquid A; sixthly, continuously neutralizing the liquid A until the PH value reaches 8, and precipitating the liquid for 3 to 4 hours; seventhly, filtering with filter paper to obtain liquid B and filter residues C; eighthly, adding the liquid B into a blending formula for conditioning according to the weight percentage of the preset volumetric yield of products; ninthly, filtering with filter paper to discharge the residues; tenthly, filling with the liquid and sterilizing to obtain a pearl liquid or pearl liquid ginseng liquid product; eleventhly, drying, crushing and packaging the filter residues C to obtain a calcium citrate supplementing agent; twelfthly, drying, crushing and packaging the liquid A.