Method for recycling sulfosalicylic acid from doxycycline production waste liquid

A technology of sulfosalicylic acid and sodium sulfosalicylate, which is applied to the preparation of sulfonate salts, chemical instruments and methods, and the preparation of organic compounds, and can solve the problems of high cost of ion exchange equipment and resin, and recovery of sulfowater. Problems such as high cost of salicylic acid and low ion exchange effluent concentration have achieved significant economic and social benefits, are conducive to environmental protection, and reduce emissions
CN105348154AActive Publication Date: 2016-02-24开封豫港制药有限公司 +2
4 Cites 7 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
开封豫港制药有限公司
Publication Date
2016-02-24
Patent Text Reader

Abstract

The invention discloses a method for recycling sulfosalicylic acid from doxycycline production waste liquid and belongs to the field of medicinal chemistry separation and purification. The method includes the following steps that alkali is added to doxycycline production waste liquid, the alkali reacts with sulfosalicylic acid in the doxycycline production waste liquid, sulfosalicylic acid sodium salt is formed, then ethyl alcohol is recycled, crystallization is conducted, and sodium sulfosalicylate is obtained; the recycled sulfosalicylic acid sodium salt is added to an alcohol solution and an acid solution, after a reaction is ended, filtering is conducted, sodium chloride is removed, filter liquor is concentrated, solvent is recycled, crystallization is conducted, sulfosalicylic acid is obtained, the recycling rate reaches 80% or more, and a product is acceptable in quality. Compared with a traditional recycling process, the sulfosalicylic acid is recycled from the doxycycline production waste liquid, emission of pollutants is reduced, environmental protection is facilitated, the sulfosalicylic acid can be recycled, the production cost is lowered, and the economic and social benefits of doxycycline are raised.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a method for recovering sulfosalicylic acid in doxycycline production waste liquid, belonging to the field of separation and purification of medicinal chemistry. Background technique

[0002] Doxycycline, also known as doxycycline or deoxyterraeum, is a long-acting broad-spectrum semi-synthetic tetracycline antibiotic. Mycoplasma, Mycoplasma trachomatis, amoeba, etc., especially the common bacteria in the respiratory tract of patients with chronic bronchitis are more sensitive to doxycycline hydrochloride. In recent years, researchers have found that doxycycline hydrochloride is more sensitive to anthrax bacteria, Vibrio cholerae, etc., and small doses of doxycycline hydrochloride can inhibit vascular coronary sclerosis, thus further stimulating the market demand for doxycycline hydrochloride.

[0003] At present, the production process of doxycycline hydrochloride all uses oxytetracycline as raw material, undergoes processes ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More