Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of preparation method and application of polyvinyl alcohol diazo polymer

A technology of polyvinyl alcohol diazo and polyvinyl alcohol, which is applied in the field of polymerization, can solve problems such as poor coating stability and complicated coating process, and achieve the effects of good repeatability, simple and quick preparation process, and good hydrophilicity

Active Publication Date: 2018-03-30
QINGDAO UNIV
View PDF8 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] For this reason, the technical problem to be solved by the present invention lies in the problem that the existing capillary wall coating material coating process is complicated and the coating stability is poor, and then provides a kind of preparation method of polyvinyl alcohol diazo polymer, described polyvinyl alcohol diazo polymer Under the action of the driving force of the syringe, the polyvinyl alcohol diazo polymer assembles and grows on the inner wall of the quartz capillary. After ultraviolet light, the polyvinyl alcohol diazo polymer undergoes a photocuring cross-linking reaction with the silicon hydroxyl on the inner wall of the capillary to construct a coating. Floor

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of preparation method and application of polyvinyl alcohol diazo polymer
  • A kind of preparation method and application of polyvinyl alcohol diazo polymer
  • A kind of preparation method and application of polyvinyl alcohol diazo polymer

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0049] The preparation method of the polyvinyl alcohol diazo polymer of the present invention comprises the following steps:

[0050] A polyvinyl alcohol diazo polymer, it has the structure shown in formula (1):

[0051]

[0052] Where m is an integer of 5-10, and n is an integer of 8-15.

[0053] Its synthetic process route is as follows:

[0054]

[0055] The method for activating a capillary bare column of the present invention comprises the following steps:

[0056] successively used 0.1mol·L -1 of sodium hydroxide solution, distilled water, 0.1mol·L -1 The bare capillary column was rinsed with hydrochloric acid solution, distilled water and methanol for 30min, 10min, 30min, 10min and 10min respectively, and finally with N 2 Blow dry the bare capillary column to obtain an activated bare capillary column.

Embodiment 1

[0058] A preparation method of polyvinyl alcohol diazo polymer, comprising the steps:

[0059] S1. Synthesis of chlorinated polyvinyl acetate (PVAc-Cl):

[0060] The dried vinyl acetate (VAc) was dissolved in acetone, and then the initiator azobisisobutyronitrile (AIBN) and the chain transfer agent carbon tetrachloride (CCl 4 ) was added to the round-bottomed flask; wherein the molar ratios of vinyl acetate to azobisisobutyronitrile and carbon tetrachloride were 1:0.001 and 1:0.03, respectively. After 3 times of nitrogen and vacuum pumping, the air was driven off to form an inert atmosphere, and the reaction was carried out at 60 °C for 6 h under reflux conditions. The product was then dissolved in methanol and precipitated with water. Repeated 3 times until a pale yellow solid was obtained, which was dried in vacuo. to constant weight to obtain the product chloropolyvinyl acetate;

[0061] S2. Synthesis of polyvinyl acetate-b-polystyrene (P(VAc-b-St)):

[0062] The catalys...

Embodiment 2

[0077] A preparation method of polyvinyl alcohol diazo polymer, comprising the steps:

[0078] S1. Synthesis of chlorinated polyvinyl acetate:

[0079] The dried vinyl acetate (VAc) was dissolved in N,N-dimethylformamide, and then the initiator azobisisobutyronitrile (AIBN) and the chain transfer agent carbon tetrachloride (CCl 4 ) was added to the round-bottomed flask; wherein the molar ratios of vinyl acetate to azobisisobutyronitrile and carbon tetrachloride were 1:0.002 and 1:0.04, respectively. After 3 times of nitrogen and vacuum pumping to drive out the air to form an inert atmosphere, the reaction was carried out at 50 °C for 5 hours under reflux conditions, and then the product was dissolved in methanol and precipitated with water, repeated twice until a pale yellow solid was obtained, which was dried in vacuo to constant weight to obtain the product macroinitiator chloropolyvinyl acetate;

[0080] S2. Synthesis of polyvinyl acetate-b-polystyrene (P(VAc-b-St)):

[...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a polyvinyl alcohol diazo polymer which has the structure shown in the formula (1). The polyvinyl alcohol diazo polymer is obtained by grafting and modifying polyvinyl alcohol. After the polyvinyl alcohol diazo polymer is irradiated by ultraviolet light, the polyvinyl alcohol diazo polymer and silicon hydroxyl on the inner wall of a capillary tube are subjected to a photocuring cross-linking reaction to form a coating. The coating can be prepared in a water phase in a self-assembly mode, and the preparation process is simple and fast. Chemical bonding of the coating is achieved through the photocuring cross-linking reaction of the light-sensitive polyvinyl alcohol diazo polymer, the quality problems of capillary tube blocking and the like are not likely to occur, the separation speed is high, and protein is separated more thoroughly. The formula can be seen in the description.

Description

technical field [0001] The invention relates to the field of polymerization, in particular to a preparation method of a polyvinyl alcohol diazo polymer, and the use of the polyvinyl alcohol diazo polymer to perform electrostatic self-assembly and photocuring cross-linking reaction to form stable covalent bonds on the inner wall of a capillary tube combined capillary coating. Background technique [0002] In recent years, capillary electrophoresis has been widely used in the fields of drug testing, life sciences, environmental protection and food testing, especially in various It has been rapidly developed and widely used in the separation and analysis of biological macromolecules such as proteins and RNA. However, due to the influence of electrostatic interaction, van der Waals force and hydrogen bond interaction with the protein on the inner surface of the unmodified capillary, non-specific adsorption occurs on the inner wall of the capillary, which affects the separation ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C08F293/00C08F8/30C08F8/04C08F8/12C09D153/00C03C17/28C12N9/36C12N9/22C07K14/765C07K1/14
CPCC03C17/004C03C17/28C07K14/765C08F8/30C08F293/005C09D153/00C12N9/22C12N9/2462C12Y302/01017C08F8/04C08F8/12
Inventor 于冰丛海林陈新
Owner QINGDAO UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com