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Pharmaceutical composition for treating gastric cancer and preparation method of pharmaceutical composition

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, hydroxyl compound active ingredients, etc., can solve problems such as recurrence, high probability of metastasis, poor surgical efficacy, adverse drug reactions, etc., achieve significant curative effect, improve human immunity The effect of accelerating the death of cancer cells

Inactive Publication Date: 2016-09-21
柳欲晓
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For a long time, due to the late discovery of gastric cancer, most of which are advanced tumors, the curative effect of surgery is not good, and the 5-year survival rate after surgery has been maintained at about 30%. Chemotherapy is to use chemical drugs to prevent the proliferation, invasion, and metastasis of cancer cells until A treatment that ultimately kills cancer cells will inevitably damage the normal cells of the human body while killing cancer cells, resulting in adverse drug reactions; radiotherapy uses high-energy electromagnetic radiation to A treatment method that changes the molecular structure to achieve the purpose of destroying cancer cells. The above three methods usually have a high probability of recurrence and metastasis, large side effects and low survival rate.

Method used

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  • Pharmaceutical composition for treating gastric cancer and preparation method of pharmaceutical composition
  • Pharmaceutical composition for treating gastric cancer and preparation method of pharmaceutical composition

Examples

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Comparison scheme
Effect test

Embodiment 1

[0015] A pharmaceutical composition for treating gastric cancer, which is composed of the following ingredients in parts by weight: 20 parts of quercetin, 19 parts of lobelialine, 18 parts of camptothecin, 17 parts of mushroom polysaccharide, 16 parts of ergosterol, and 14 parts of maytansin , 13 parts of Nanshan vine glycoside Ap1, 12 parts of hairy wax gourd root extract, 11 parts of Sophora japonica extract, 10 parts of bark seed extract, 8 parts of paeonol, 6 parts of amygdalin, 4 parts of dandelion cyperol, 2 parts of β-stigmasterol, 0.03 parts of vitamin A.

[0016] The preparation method of the pharmaceutical composition for treating gastric cancer is as follows: extracting the weight components of quercetin, lobelialine, camptothecin, mushroom polysaccharide, ergosterol, maytansin, nanshan vine glycoside Ap1, and wax gourd root extract, paeonol, paeonol, paeonol, dandelionol, β-stigmasterol, and vitamin A, mixed with a blender, dried, crushed into 110-mesh fine powder,...

Embodiment 2

[0019] A nursing medicine for preventing complications after liver injury, which is composed of the following components by weight: 29.5 parts of quercetin, 28.5 parts of lobelialine, 27 parts of camptothecin, 26 parts of mushroom polysaccharide, 25 parts of ergosterol 23 parts, Mei Deng Xin, 21.5 parts of Nanshan vine glycoside Ap1, 20.5 parts of hairy winter melon root extract, 19 parts of Sophora vine extract, 18 parts of Po Luo seed extract, 16.5 parts of paeonol, 13 parts of amygdalin, Dandelion Cylinol 11 parts, β-stigmasterol 7 parts, vitamin A 0.14 parts.

[0020] The preparation method of the pharmaceutical composition for treating gastric cancer is as follows: extracting the weight components of quercetin, lobelialine, camptothecin, mushroom polysaccharide, ergosterol, maytansin, nanshan vine glycoside Ap1, and wax gourd root extract, paeonol, paeonol, paeonol, dandelionol, β-stigmasterol, and vitamin A, mixed with a blender, dried, crushed into 110-mesh fine powder,...

Embodiment 3

[0023] A nursing medicine for preventing complications after liver injury, which is composed of the following components by weight: 39 parts of quercetin, 38 parts of lobelialine, 36 parts of camptothecin, 35 parts of mushroom polysaccharide, 34 parts of ergosterol 32 parts, Mei Dengxin 32 parts, nanshan vine glycoside Ap1 30 parts, hairy wax gourd root extract 29 parts, Sophora japonica extract 27 parts, sire seed extract 26 parts, paeonol 25 parts, amygdalin 20 parts, Dandelion Cylinol 18 parts, β-stigmasterol 12 parts, vitamin A 0.25 parts.

[0024] The preparation method of the pharmaceutical composition for treating gastric cancer is as follows: extracting the weight components of quercetin, lobelialine, camptothecin, mushroom polysaccharide, ergosterol, maytansin, nanshan vine glycoside Ap1, and wax gourd root extract, paeonol, paeonol, paeonol, dandelionol, β-stigmasterol, and vitamin A, mixed with a blender, dried, crushed into 110-mesh fine powder, and sterilized Aft...

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Abstract

The invention discloses a pharmaceutical composition for treating gastric cancer and a preparation method of the pharmaceutical composition. The pharmaceutical composition for treating the gastric cancer consists of the following ingredients in parts by weight: dried mushroom polysaccharides, lobelia chinensis lour. alkaloids, paeonol, quercetin ketone, ergosterol, maytansine, dregeoside Ap1, a hair wax gourd root extract, an oxystelma esculentum extract, a semen aesculi extract, camptothecin, tetragonin, taraxerol, [beta]-stigmasterol and vitamin A. The pharmaceutical composition disclosed by the invention, which combines Western medicines and active ingredients of a plurality of traditional Chinese medicines, has functions of inhibiting the growth of cancer cells, enhancing the necrosis degree of the cancer cells, harmonizing stomach and relieving pain, clearing heat and inducing diuresis, promoting blood circulation and relieving swelling; and the pharmaceutical composition is capable of boosting human immunity and relieving poor appetite of patients; and the pharmaceutical composition is low in side effect, obvious in curative effect, and is capable of prolonging the survival time of the patients with the gastric cancer and improving life quality.

Description

technical field [0001] The invention relates to the technical field of gastric cancer medication, in particular to a pharmaceutical composition for treating gastric cancer and a preparation method thereof. Background technique [0002] Gastric cancer is a malignant tumor derived from the gastric mucosal epithelium, accounting for the third of all malignant tumors and the first of digestive tract malignant tumors, accounting for 95% of gastric malignant tumors. It can be seen that gastric cancer is a common disease that threatens human health. According to statistics from relevant departments, there are 900,000 to 960,000 new gastric cancer patients in the world every year, and more than 700,000 people die of gastric cancer every year. The incidence of gastric cancer increases significantly with age, and the peak age of onset is between 48 and 80 years old. According to the results of the second national cause of death survey organized by the Ministry of Health, the death rat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/27A61K31/537A61K31/352A61K31/445A61K31/4745A61K31/715A61K31/704A61K31/12A61K31/56A61K31/575A61K31/07A61P35/00
CPCA61K9/4866A61K31/07A61K31/12A61K31/352A61K31/445A61K31/4745A61K31/537A61K31/56A61K31/575A61K31/704A61K31/715A61K36/185A61K36/27A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2300/00
Inventor 柳欲晓刘炳慧
Owner 柳欲晓
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