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Nutrient composition and application thereof in preparation of medicines for treating aplastic anemia

A nutritional composition and vitamin technology, applied in the field of life sciences, can solve the problems of DNA repair ability reduction, failure to correct, hematopoietic microenvironment support function defects, etc., and achieve the effect of treating aplastic anemia

Inactive Publication Date: 2016-11-16
吴文国 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] ②The DNA repair ability of SAA patients (severe aplastic anemia) is significantly reduced, which cannot be corrected after treatment with anti-lymphocyte globulin (ALG);
[0010] (3) Hematopoietic microenvironment support function defect
Although the above-mentioned nutritional composition has the described function, due to the limitation of the effect, the nutritional composition is only suitable for the treatment of malnutrition anemia (iron deficiency anemia and folic acid and vitamin B 12 malnutrition anemia), anemia caused by decreased red blood cell production, and anemia caused by excessive destruction or loss of red blood cells, and cannot be used as a drug for the treatment of aplastic anemia

Method used

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  • Nutrient composition and application thereof in preparation of medicines for treating aplastic anemia
  • Nutrient composition and application thereof in preparation of medicines for treating aplastic anemia
  • Nutrient composition and application thereof in preparation of medicines for treating aplastic anemia

Examples

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Effect test

Embodiment 1

[0052] Example 1: The mass (mg) ratio of each component of the nutritional composition of the present invention is as follows: lysine 200-1200, methionine 100-1600, phenylalanine 150-1400, threonine 50-600, Tryptophan 50~400, Arginine 200~1500, Histidine 100~1000, Glycine 100~600, Aspartic Acid 100~600, Leucine 100~600, Isoleucine 100~600, Valine Amino acid 100~800, Serine 100~400, Glutamine 200~600, Taurine 100~500, Orotic acid 100~300, Nucleotide 200~1200, Vitamin A 0.2~0.6, Vitamin D 0.002~0.006 , Vitamin B 2 1~4, vitamin B 6 1~4, vitamin B 12 0.001~0.006, niacin 5~20, folic acid 0.01~1.2, vitamin C 50~150, iron 2~10, zinc 2~10, manganese 2~10, copper 0.5~2, selenium 0.01~0.1, chromium 0.01~0.02 , potassium 10~300, calcium 100~300, magnesium 100~200, inositol 50~60, soybean lecithin 100~2500.

Embodiment 2

[0053] Example 2: The mass (mg) ratio of each component is as follows: lysine 600, methionine 800, phenylalanine 700, threonine 300, tryptophan 200, arginine 760, histidine 500 , Glycine 300, Aspartic Acid 300, Leucine 300, Isoleucine 300, Valine 400, Serine 200, Glutamine 300, Taurine 500, Orotic Acid 300, Nucleotide 400, Vitamin A0.6, vitamin D0.006, vitamin B 2 2. Vitamin B 6 2. Vitamin B 12 0.004, niacin 12, folic acid 0.9, vitamin C100, iron 10, zinc 10, manganese 8, copper 2, selenium 0.1, chromium 0.02, potassium 300, calcium 300, magnesium 200, inositol 60, soybean lecithin 1200.

[0054] The nutritional composition can be used in the preparation of medicines for treating aplastic anemia.

[0055] The sources of raw materials are shown in Table 1:

[0056] Table 1

[0057]

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Abstract

The invention discloses a nutrient composition and application thereof in preparation of medicines for treating aplastic anemia. The nutrient composition is prepared from the following components according to ratios: lysine, methionine, phenylalanine, threonine, tryptophan, arginine, histidine, glycine, aspartic acid, leucine, isoleucine, valine, serine, glutamine, taurine, orotic acid, nucleotide, vitamin A, vitamin D, vitamin B2, vitamin B6, vitamin B12, niacin, folic acid, vitamin C, iron, zinc, manganese, copper, selenium, chromium, potassium, calcium, magnesium, inositol and granulesten. Aplastic anemia body can be comprehensively repaired, so that an effect of treating aplastic anemia is achieved.

Description

technical field [0001] The invention relates to preventive medicine and therapeutic medicine in the field of life sciences, in particular to a nutritional composition and its application in the preparation of medicines for treating aplastic anemia. Background technique [0002] Aplastic anemia (Aplastic Anemia) is a group of bone marrow hematopoietic failure caused by chemical substances, biological factors, radiation or unknown reasons, characterized by hematopoietic stem cell damage, bone marrow fat, and peripheral blood pancytopenia. The pathogenesis of aplastic anemia is extremely complex, and it is currently believed to be related to the following aspects: [0003] (1) Intrinsic proliferation defect of hematopoietic stem cells [0004] ①Hematopoietic stem cells in the bone marrow of aplastic anemia are significantly reduced, and the colony formation ability of hematopoietic stem cells is significantly reduced, and abnormal hematopoietic stem cells can inhibit the funct...

Claims

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Application Information

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IPC IPC(8): A61K33/34A61P3/02A61P7/06A61K31/198A61K31/047A61K31/07A61K31/185A61K31/195A61K31/375A61K31/405A61K31/4172A61K31/4415A61K31/455A61K31/513A61K31/519A61K31/525A61K31/59A61K31/685A61K31/7052A61K31/714A61K33/00A61K33/04A61K33/06A61K33/24A61K33/26A61K33/30A61K33/32
CPCA61K31/198A61K31/047A61K31/07A61K31/185A61K31/195A61K31/375A61K31/405A61K31/4172A61K31/4415A61K31/455A61K31/513A61K31/519A61K31/525A61K31/59A61K31/685A61K31/7052A61K31/714A61K33/00A61K33/04A61K33/06A61K33/24A61K33/26A61K33/30A61K33/32A61K33/34A61K2300/00
Inventor 吴文国贾莉杨佩满
Owner 吴文国
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