Preparation method of stable and high-performance implant surface

A high-performance implant technology, applied in prostheses, pharmaceutical formulations, coatings, etc., can solve the problems of decreased surface activity, poor osseointegration, unpredictable implant results, etc. Bone performance and success rate, the effect of excellent cell growth

Active Publication Date: 2017-06-27
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the storage of pure titanium implants, their surface activity dec...

Method used

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  • Preparation method of stable and high-performance implant surface
  • Preparation method of stable and high-performance implant surface
  • Preparation method of stable and high-performance implant surface

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The titanium implant with a smooth surface is sprayed evenly with 40-60 mesh emery under 5 bar pressure for 60 seconds, and the sprayed implant is cleaned with acetone, ethanol and pure water under ultrasonic conditions for 15 minutes, and then washed with a large amount of pure water clean and blow dry with nitrogen.

[0028] Then directly put into a fully dissolved oxalic acid solution with a mass concentration of 37.5% in a boiling water bath for 60 minutes, rinse with a large amount of water, and blow dry with nitrogen.

[0029] The above-mentioned implants treated with oxalic acid were treated at 500° C. for 30 minutes, and then cooled naturally at room temperature.

Embodiment 2

[0031] The titanium implant with a smooth surface is sprayed evenly with 40-60 mesh emery under 5 bar pressure for 60 seconds, and the sprayed implant is cleaned with acetone, ethanol and pure water under ultrasonic conditions for 15 minutes, and then washed with a large amount of pure water clean and blow dry with nitrogen.

[0032] Then directly put into a fully dissolved oxalic acid solution with a mass concentration of 37.5% in a boiling water bath for 60 minutes, rinse with a large amount of water, and blow dry with nitrogen.

[0033] The above-mentioned oxalic acid-treated implants were treated at 500° C. for 60 minutes, and cooled naturally at room temperature.

Embodiment 3

[0035] The surfaces prepared in Examples 1 and 2 were used for field emission scanning electron microscope morphology observation. figure 1 Showing its morphological characteristics, the temperature treatment process basically maintains the microstructure before the temperature treatment.

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Abstract

The invention provides a preparation method of a stable and high-performance titanium implant surface. The preparation method comprises three key steps of sand blasting, acid etching and temperature processing or four key steps of sand blasting, acid etching, secondary acid etching/alkali treatment and temperature processing, wherein sand blasting is carried out by virtue of titanium or titanium alloy, acid etching is carried out for a certain time by virtue of an oxalic acid system or an H2SO4/HCl system or an HF/HNO3 system at a certain temperature, and finally, a micron-scale structural surface is directly subjected to temperature processing or is subjected to acid etching or alkali treatment before temperature processing. According to the preparation method, a large-scale fluctuation structure is obtained through sand blasting, a micron-scale structure/micron-nanometer composite structure is obtained through acid etching, an implant surface with a titanium oxide crystal form and a micron-nanometer composite structure is obtained through temperature processing, and crystalline titanium oxide is obtained by the surface when an original micron-nanometer structure is maintained, so that the surface has good bone integrating capacity, is very stable under a natural storage condition and has good ageing resistance and excellent broad-spectrum antimicrobial ability in a window phase.

Description

technical field [0001] The invention belongs to the technical field of medical material manufacturing, and relates to a stable and high-performance implant surface preparation method, in particular to a stable and high-performance titanium-based implant surface preparation method. [0002] technical background [0003] Since the theory of osseointegration was proposed in the middle of the 20th century, the research and application of implants have made remarkable progress. Because implant restoration is supported by artificial tooth roots, it does not need to grind away healthy adjacent teeth. It has high chewing efficiency, less foreign body sensation, no damage to adjacent teeth, and is durable. It can achieve good aesthetics and functional restoration effects in all cases, so it is favored by the majority of patients with edentulousness, and is known as "the third set of teeth for human beings". Implant technology has become a routine treatment method for the treatment of...

Claims

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Application Information

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IPC IPC(8): A61L27/06A61L27/30A61L27/54A61L27/56C23F1/26C23C8/10C23F1/38C22F1/18C23F17/00B24C1/00
CPCA61L27/06A61L27/306A61L27/54A61L27/56A61L2300/404A61L2400/18B24C1/00C22F1/183C23C8/10C23F1/26C23F1/38C23F17/00
Inventor 李晓东罗巧洁
Owner ZHEJIANG UNIV
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