Composition for inhibiting growth of candida albicans and preparation method and application thereof
A technology of Candida albicans and composition, which is applied in the field of compositions for inhibiting the growth of Candida albicans, can solve the problems of widespread emergence of drug-resistant strains and increase the difficulty of treatment, achieve safety and no side effects, improve medication compliance, and produce low cost effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
preparation example Construction
[0027] Preferably, the components also include a third component, and the mass ratio of the third component to the first component is (3-5): 10; the preparation method of the third component comprises the following steps: combining perilla leaf, Artemisia argyi and Comfrey leaves are mixed evenly, and then soaked in rice wine with an alcohol content of 15% to 25% for 10 to 15 hours; the soaked mixture is heated at 60 to 70°C for 100 to 120 minutes, filtered, and the filtrate is collected; the filtrate is decolorized, It is then concentrated into an extract with a relative density of 1.2-1.3 measured at 80°C to obtain the third component; wherein the ratio of the total mass of perilla leaves, mugwort leaves and comfrey leaves to the mass of rice wine is (1-2):10 .
[0028] In addition, the present invention also provides a preparation method of the composition for inhibiting the growth of Candida albicans, comprising the following steps:
[0029] After uniformly mixing all the...
Embodiment 1
[0032] This embodiment provides a composition for inhibiting the growth of Candida albicans, comprising a first component and a second component, and the mass ratio of the first component to the second component is 10:1;
[0033] Wherein, the first component includes: a fermentation product obtained by fermentation of Streptomyces griseus and Streptomyces globisporus;
[0034] The fermentation method comprises the steps of:
[0035] S101: Inoculate the activated Streptomyces griseus into the fermentation medium, and the inoculum content is (5-10)×10 6 cfu / mL, fermented at 36°C for 8 hours, during the fermentation process: the ventilation rate is 0.1v / v min, the stirring speed is 120rpm; the pH value of the fermentation medium is 7.2, and the composition of the fermentation medium includes: glucose 2g / L , starch 5g / L, peptone 0.1g / L, yeast extract 0.4g / L, peanut cake powder 2g / L, soybean cake powder 10g / L, sodium chloride 0.2g / L, magnesium sulfate 0.5g / L, hydrogen phosphate D...
Embodiment 2
[0042] This embodiment provides a composition for inhibiting the growth of Candida albicans, comprising a first component and a second component, and the mass ratio of the first component to the second component is 10:2;
[0043] Wherein, the first component includes: a fermentation product obtained by fermentation of Streptomyces griseus and Streptomyces globisporus;
[0044] The fermentation method comprises the steps of:
[0045] S101: Inoculate the activated Streptomyces griseus into the fermentation medium, and the inoculum content is (5-10)×10 6 cfu / mL, fermented at 38°C for 10 hours, during the fermentation process: the ventilation rate is 0.2v / v min, the stirring speed is 150rpm; the pH value of the fermentation medium is 7.2, and the composition of the fermentation medium includes: glucose 2g / L , starch 5g / L, peptone 0.1g / L, yeast extract 0.4g / L, peanut cake powder 2g / L, soybean cake powder 10g / L, sodium chloride 0.2g / L, magnesium sulfate 0.5g / L, hydrogen phosphate ...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com