Acne gel containing traditional Chinese medicine components and preparation method thereof

A technology of acne and traditional Chinese medicine, applied in the field of acne gel and its preparation, can solve the problems of easy recurrence of acne and slow treatment of acne, and achieve the effects of improving antioxidant capacity, promoting skin self-healing, and long-lasting effect

Inactive Publication Date: 2017-11-10
SHANDONG ACAD OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the problems that current pure traditional Chinese medicine ingredients are slow in curative effect on acne, and western medicine ingre

Method used

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  • Acne gel containing traditional Chinese medicine components and preparation method thereof
  • Acne gel containing traditional Chinese medicine components and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1 Preparation of traditional Chinese medicine extract for treating acne.

[0035] Ingredients (parts by weight): Coptidis 50, Scutellaria baicalensis 40, Forsythia 50, Nepeta 40, Fangfeng 40, Gardenia 30, Citrus aurantium 40, Sophora flavescens 50, Dandelion 150, Calendula 30, Tribulus terrestris 30, Angelica dahurica 50, Radix Paeoniae Alba 40, Poria 50, Licorice 30.

[0036] Preparation:

[0037] (1) Weigh each raw material and pulverize it into 200 mesh powder to obtain mixed powder;

[0038] (2) Add the above mixed powder to 3 times the weight of water, and extract at 100°C for 3 hours to obtain the extract;

[0039] (3) Concentrate the above extract to 1 / 5 of the original volume to obtain the Chinese medicine extract for treating acne.

Embodiment 2

[0040] Example 2 Preparation of acne gel containing traditional Chinese medicine ingredients.

[0041] Formula (g):

[0042] Chinese medicine extract 500 in embodiment 1, sulfur 5, toad venom 3, vitamin B 6 10. Vitamin C Glucoside 5, Zinc Chloride 5, Allantoin 0.8, Ethanol 5, Glycerin 50, Carbomer 940 5, Polysorbate 80 0.5, Phenoxyethanol 0.5, Triethanolamine 7.5.

[0043] Preparation:

[0044] (1) Add phenoxyethanol, vitamin B 6 , vitamin C glucoside, zinc chloride and allantoin are dissolved in the traditional Chinese medicine extract;

[0045] (2) Stir toad venom and polysorbate 80 in ethanol evenly, add sulfur powder and stir to form a uniformly distributed liquid;

[0046] (3) Grind Carbomer 940 and glycerin and swell in water, then add triethanolamine and stir to add the solutions of steps (1) and (2), and mix well to obtain an acne gel containing traditional Chinese medicine ingredients.

Embodiment 3

[0047] Example 3 Validation of the effect of acne gel containing traditional Chinese medicine ingredients.

[0048] The volunteers who participated in the experiment were patients from the dermatology department of a hospital, all of whom had facial acne. There were 40 cases in the test group and 10 cases in the control group. The main facial skin symptoms are as follows: there are pustules on the facial skin, especially on the cheeks, and sebaceous cysts of various sizes, and the skin is light red or dark red.

[0049] 2.1 How to use

[0050] The test group used the acne gel in Example 2 for 60 days in the following way: after cleansing the face at night, apply it to the affected area, avoiding the mouth, nose and eyes; wash the face in the morning of the second day.

[0051] The control group did not use any external medicine.

[0052] 2.2 Use effect evaluation

[0053] Evaluate the use effect of the acne gel according to the following evaluation criteria, and the use ef...

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Abstract

The present invention provides an acne gel containing traditional Chinese medicine components, the acne gel containing the traditional Chinese medicine components comprises the following active ingredients by weight: 250-1000 parts of acne treatment traditional Chinese medicine extract, 5-8 parts of sulfur, 3-5 parts of venenum bufonis, 5-15 parts of vitamin B6, 1-5 parts of vitamin C glucoside, 5-10 parts of zinc chloride, 0.5-1 part of Allantoin, 0.5-1%wt of an excipient, 0.05-0.15%wt of a surfactant, 0-1%wt of a preservative and 5-10%wt of a solvent; the acne treatment traditional Chinese medicine extract comprises the following raw materials by weight: 30-50 parts of Coptis chinensis, 40-50 parts of Scutellaria baicalensis, 40-50 parts of herba schizonepetae, 30-50 parts of fructus forsythiae, 40-50 parts of radices sileris, 30-50 parts of Fructus Gardeniae, 40-50 parts of immature bitter orange, 50-100 parts of radix sophorae flavescentis, 100-200 parts of dandelion, 30-40 parts of calendula officinalis, 20-30 parts of Tribulus terrestris, 40-50 parts of radix angelicae, 40-50 parts of radix paeoniae alba, 40-50 parts of Poria cocos and 20-40 parts of licorice. The acne gel containing the traditional Chinese medicine components does not contain hormones and antibiotics, and is safer to use, after drug withdrawal, acnes are not easy to recur, and the acne gel containing the traditional Chinese medicine components has the advantages of anti-inflammatory, antipruritic and detoxification effects, long duration and few toxic and side effect, and can also complement skin nutrition, improve the antioxidant capacity of the skin, promote skin healing and eliminate pockmarks.

Description

technical field [0001] The invention relates to an acne gel containing traditional Chinese medicine ingredients and a preparation method thereof, belonging to the field of medicine and pharmacy. Background technique [0002] Acne is a multifactorial disease. It is currently known that its pathogenesis is related to factors such as sex hormone levels, massive secretion of sebaceous glands, proliferation of Propionibacterium acnes, abnormal keratinization of pilosebaceous gland ducts, and inflammation. Usually, acne is apt to occur in adolescent male or female, and individual patient also can extend to more than 30 years old. Although acne is a disease with a tendency to self-heal, acne itself and the scars caused by untimely acne treatment will seriously affect the quality of life of patients, causing mental stress and economic burden for patients. Therefore, drugs for the treatment of acne are research hotspots in this field. [0003] In Chinese medicine, acne is called "ac...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K9/06A61P17/10A61K31/4166A61K31/4415A61K31/7048A61K33/04A61K33/30A61K35/65
CPCA61K9/06A61K31/4166A61K31/4415A61K31/7048A61K33/04A61K33/30A61K35/65A61K36/076A61K36/185A61K36/232A61K36/238A61K36/28A61K36/288A61K36/484A61K36/489A61K36/538A61K36/539A61K36/634A61K36/65A61K36/71A61K36/718A61K36/744A61K36/752A61K47/10A61K47/32A61K47/38A61K2300/00
Inventor 裴利红谭庆坤高琛李泠玥
Owner SHANDONG ACAD OF CHINESE MEDICINE
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