Method for preparing benzil by performing catalytic oxidation on benzoin

A technology for catalytic oxidation and benzoin, applied in the preparation of carbon-based compounds, chemical instruments and methods, preparation of organic compounds, etc., can solve the problems of complicated preparation of complexes, high yield of benzil, and short reaction time, and achieves economical The effect of removing catalyst preparation process and reaction process is green and environmentally friendly, and the reaction conditions are mild

Inactive Publication Date: 2018-04-13
DALIAN UNIV OF TECH
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  • Abstract
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Problems solved by technology

Catalysis Communications (2009,10,1931–1935) reported air as oxidant, toluene as solvent, Pd/SiO 2 It is used as a catalyst to catalyze the oxidation of benzoin at 100°C to prepare benzil. The yield of benzil is 98% after reaction for 0.75h. The reaction conditions are mild, the reaction time is short, and the yield of benzil is high, but the catalyst is expensive and the reaction cost high, not conducive to industrial production
Journal of Chemical Sciences (2014, 126, 111-115) reported that at room temperature, molecular oxygen or air was used as an oxidant, p-xylene was used as a solvent, and Co(Salen) complex was used as a catalyst to catalyze the o...

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  • Method for preparing benzil by performing catalytic oxidation on benzoin
  • Method for preparing benzil by performing catalytic oxidation on benzoin
  • Method for preparing benzil by performing catalytic oxidation on benzoin

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Experimental program
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Effect test

Embodiment 1-9

[0024] Embodiment 1-9: The impact of different catalyst types on the conversion rate of benzoin and the selectivity of benzil, the specific experimental process is described as follows:

[0025] 5mmol benzoin, 2mol% vanadyl oxy compound, 2mol% nitrite, 10ml acetonitrile are added in the 25ml reactor, after the reactor is sealed, fill the reactor with 0.5MPaO 2 , the temperature was raised to 100° C. under stirring, and kept for 6 hours. After the reaction was completed, it was cooled to room temperature, and the product was analyzed quantitatively by gas chromatography.

[0026] Table 1: The effect of different catalyst types on the conversion rate of benzoin and the selectivity of benzil

[0027]

Embodiment 10-15

[0028] Embodiment 10-15: The addition amount of catalyst affects the conversion rate of benzoin and the selectivity of benzil, and the specific experimental process is described as follows:

[0029] A certain amount of catalyst (vanadyl sulfate / tert-butyl nitrite=100mol%), 5mmol benzoin, and 10ml acetonitrile are added in a 25ml reactor, and 0.5MPa O is charged in the reactor. 2 , the temperature was raised to 100° C. under stirring, and kept for 6 hours. After the reaction was completed, it was cooled to room temperature, and the product was analyzed quantitatively by gas chromatography.

[0030] Table 2: The effect of the amount of catalyst added on the conversion rate of benzoin and the selectivity of benzil

[0031]

[0032]

Embodiment 16-19

[0033] Embodiment 16-19: the influence of the molar ratio of nitrite and vanadyl compound on the conversion rate of benzoin and the selectivity of benzil, the specific experimental process is described as follows:

[0034] 5mmol benzoin, 2mol% vanadyl sulfate, a certain amount of nitrite, 10ml acetonitrile add in the 25ml reactor, fill in 0.5MPa O in the reactor 2 , the temperature was raised to 100° C. under stirring, and kept for 6 hours. After the reaction was completed, it was cooled to room temperature, and the product was analyzed quantitatively by gas chromatography.

[0035] Table 3: The effect of the molar ratio of nitrite to vanadyl on the conversion of benzoin and the selectivity of benzil

[0036]

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PUM

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Abstract

The invention belongs to the technical field of preparation of benzyl and provides a method for preparing benzil by performing catalytic oxidation on benzoin. According to the method, oxygen or air serves as an oxidizing agent, a composite catalyst consists of two components, namely vanadium oxide and nitrous acid ester, and the benzyl is prepared by performing catalytic oxidation on the benzoin at 60 to 120 DEG C. Compared with the stoichiometric chemistry oxidation methods such as traditional chromate oxidation method, the nitric acid oxidation method and the permanganate oxidation method, the method has the following advantages: the reaction condition is mild, the catalyst is cheap and efficient, the reaction is green and environment-friendly, the conversion rate of the benzoin is high,the selectivity of the benzyl is high, and good application prospect and high practical value are achieved.

Description

technical field [0001] The invention belongs to the technical field of preparing benzil, and in particular relates to a composite catalyst system that catalyzes the oxidation of benzoin to prepare benzil. Background technique [0002] Benzil, also known as diphenyl ethylene dione, biphenyl, and bibenzoyl, can be used to synthesize drug phenytoin, photosensitizers, insecticides, printing inks for food packaging, and corrosion inhibitors for low-carbon steel. Important organic synthesis intermediates and organic chemical raw materials, widely used in food, medicine, pesticide and other industries. [0003] Using benzoin as raw material, there are two methods for preparing benzil by oxidizing benzoin: one is non-catalytic oxidation. Benzoin is prepared by oxidation of benzoin with inorganic compounds, metal organic compounds, polymer compounds, etc. as oxidants, but there are problems such as large amount of oxidant, violent reaction, many by-products, and serious pollution. ...

Claims

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Application Information

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IPC IPC(8): C07C45/39C07C49/784B01J31/36B01J31/22
CPCB01J31/2213B01J31/36C07C45/39C07C49/784
Inventor 杜中田鞠永伟肖楚红李幸霏孙小万
Owner DALIAN UNIV OF TECH
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