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Preparation method of hemostatic non-woven fabric capable of promoting healing

A technology of non-woven fabrics and mixtures, which is applied in the fields of non-woven fabrics, textiles, papermaking, and medical sciences. It can solve problems such as easy adhesion to the skin, inconvenient use, and inability to ensure moisture around the wound. It achieves a simple process and promotes recovery. , The effect of convenient control of process conditions

Inactive Publication Date: 2018-06-01
JIANGSU PROVINCE JIANERKANG MEDICAL DRESSING CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when the chitosan fiber non-woven fabric made by this method is applied on the wound, it can only absorb a small amount of wound effusion, and cannot ensure that the wound is moist. After the wound is healed, it is easy to adhere to the skin, which is inconvenient to use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A preparation method for promoting healing and hemostasis non-woven fabric, comprising the following steps:

[0022] (1) The chitosan ethanol solution and 30% polyacrylic acid deionized aqueous solution are mixed in proportion by the mass fraction to obtain chitosan and polyacrylic acid mixed solution, wherein the chitosan in chitosan and polyacrylic acid mixed solution is The mass ratio of sugar to polyacrylic acid is 3:7; then add the mixture of Panax notoginseng powder, Zizhucao extract and thistle extract to the mixed solution, the mass ratio of Panax notoginseng powder, Zizhucao and thistle is 10 :1.5:1, ultrasonic vibration forms electrospinning suspension;

[0023] Wherein, the extract of thistle is prepared by the following method: the extract of thistle is washed, dried and crushed, and then refluxed in a mixed solvent of ethylene glycol and ethyl acetate for 24 hours, and then concentrated to obtain the extract of thistle, wherein the volume of ethylene glycol...

Embodiment 2

[0028] A preparation method for promoting healing and hemostasis non-woven fabric, comprising the following steps:

[0029] (1) The chitosan ethanol solution and 30% polyacrylic acid deionized aqueous solution are mixed in proportion by the mass fraction to obtain chitosan and polyacrylic acid mixed solution, wherein the chitosan in chitosan and polyacrylic acid mixed solution is The mass ratio of sugar to polyacrylic acid is 3:7; then add the mixture of Panax notoginseng powder, Zizhucao extract and thistle extract to the mixed solution, the mass ratio of Panax notoginseng powder, Zizhucao and thistle is 10 :1.8:1; Ultrasonic vibration forms electrospinning suspension;

[0030] Wherein, the extract of thistle is prepared by the following method: the extract of thistle is washed, dried and crushed, and then refluxed in a mixed solvent of ethylene glycol and ethyl acetate for 24 hours, and then concentrated to obtain the extract of thistle, wherein the volume of ethylene glycol...

Embodiment 3

[0035] A preparation method for promoting healing and hemostasis non-woven fabric, comprising the following steps:

[0036] (1) The chitosan ethanol solution and 30% polyacrylic acid deionized aqueous solution are mixed in proportion by the mass fraction to obtain chitosan and polyacrylic acid mixed solution, wherein the chitosan in chitosan and polyacrylic acid mixed solution is The mass ratio of sugar to polyacrylic acid is 3:7; then add the mixture of Panax notoginseng powder, Zizhucao extract and thistle extract to the mixed solution, the mass ratio of Panax notoginseng powder, Zizhucao and thistle is 10 :2:1, ultrasonic vibration forms electrospinning suspension;

[0037] Wherein, the extract of thistle is prepared by the following method: the extract of thistle is washed, dried and crushed, and then refluxed in a mixed solvent of ethylene glycol and ethyl acetate for 24 hours, and then concentrated to obtain the extract of thistle, wherein the volume of ethylene glycol a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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PUM

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Abstract

The invention relates to the technical field of non-woven fabrics, in particular to a preparation method of a hemostatic non-woven fabric capable of promoting healing. The preparation method comprisesthe following steps: (1) proportionally mixing 2 percent by mass of chitosan ethanol solution and 30 percent by mass of polyacrylic acid deionized water solution to obtain a chitosan-polyacrylic acidmixed solution, then adding a mixture of radix notoginseng powder, Japanese beauty-berry extract and herba cepbalanoplosis segeti extract into the mixed solution, and performing ultrasonic oscillation to form an electrospinning suspension; (2) making the electrospinning solution flow through a No. 22 blunt needle of an electrospinning device injection pump at a flow rate of 2 to 4ml / h, collectingelectrospinning fiber on a rotating circular shaft of which the rotating speed is 550 to 650r / min, removing a membrane from the circular shaft, and performing vacuum drying for 48 hours to obtain thehemostatic non-woven fabric. The preparation method of the medical non-woven fabric disclosed by the invention is simple in process, and the prepared medical non-woven fabric has a hemostatic effect,an antibacterial effect and adhesion resistance.

Description

technical field [0001] The invention relates to the technical field of non-woven fabrics, in particular to a preparation method of non-woven fabrics for promoting healing and hemostasis. Background technique [0002] Chitosan is a deacetylated product of chitin, a polysaccharide substance whose chemical name is β(1-4)-2-amino-2-deoxy-D-glucan. According to literature reports, chitosan can promote the repair of nerve damage and bone joint damage, and may have a hemostatic effect. Chitosan has the characteristics of natural antibacterial, hemostasis, anti-inflammation, promotion of wound healing, reduction of wound scars and good biocompatibility. At present, there are existing technologies to wet spin chitosan into fibers and then weave them into chitosan fibers Non-woven fabrics for wound healing materials. However, when the chitosan fiber non-woven fabric made by this method is applied on the wound, it can only absorb a small amount of wound effusion, and cannot ensure th...

Claims

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Application Information

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IPC IPC(8): A61L15/40A61L15/28A61L15/24A61L15/44D04H1/4382D04H1/728
CPCA61L15/24A61L15/28A61L15/40A61L15/44A61L2300/30A61L2300/402A61L2300/412A61L2300/418A61L2300/424A61L2300/45D04H1/4382D04H1/728C08L5/08C08L33/02
Inventor 陈国平
Owner JIANGSU PROVINCE JIANERKANG MEDICAL DRESSING CO LTD
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