Stem cell extract product medical dressing, and preparation method thereof

Abstract

The invention discloses a stem cell extract product medical dressing, and a preparation method thereof, and belongs to the technical field of biological medicine. The stem cell extract product medicaldressing is a wound cover material with excellent effect, is capable of preventing bacterium infection effectively, accelerating wound healing, controlling and absorbing wound exudate, and protectingnew born tissues, possesses excellent biocompatibility, and is excellent in permeability; no toxic or side effect is caused; natural green raw materials are adopted; the adopted accessory materials are edible grade; too much bleeding and patient pain are avoided; delaying of wound healing caused by left residues is avoided; and an environment beneficial for wound healing is providing for promotion of skin regeneration. The stem cell extract product medical dressing is capable of controlling wound exudates, supplying water and maintaining humidity, relieving inflammation and swelling, relieving wound pain and other discomforts, avoiding scars left by wound, and avoiding influences on skin appearance. The stem cell extract product medical dressing is prepared through freeze drying, so thatit is more beneficial for maintenance of the activity of a large amount of cytokines and proteins, and storage and transportation under room temperature conditions can be realized.

Description

technical field [0001] The invention relates to a medical dressing of stem cell extract and a preparation method thereof, belonging to the field of biomedicine. Background technique [0002] The skin is the largest organ of the human body and acts as a barrier to protect the body. However, it is the most vulnerable to trauma. Common traumas caused by sharp objects and tools are acute wounds, which are prone to blood loss and infection, and invade the dermis. Painful and easy to leave scars, which affect the appearance of the skin; other common ones include abrasions, burns, scalds, and frostbite. This kind of trauma is a chronic wound, which generally causes soft tissue contusion, swelling and pain, and often has wound exudate. Causes blood vessel rupture and nerve damage in skin tissue and muscle, which may be more difficult to heal than acute wounds. Therefore, when the skin is wounded, it should be taken care of in time and effectively to prevent unnecessary sequelae. In...

AI Technical Summary

Problems solved by technology

However, previous studies mainly focused on wound treatment by collecting culture medium supernatant, which contained less effective active cytokines and many foreign substances, including apoptotic cells and cell debris. Difficult to store stably, easy to pollute, causing many negative problems, not conducive to standardized production and preparation

Existing technologies cannot maximize the use of active ingredients in stem cell cultures. Existing technologies extract cytokines secreted by stem cells, mostly using dialysis, and the resulting extracts have very limited effects on wound healing

[0011] 2. Most of the gel dressings in the prior art are cell suspensions made of stem cells, and the activity is difficult to maintain. In the suspension state, the activity of stem cells decreases rapidly (the best use time is within 48 hours), and its application has great limitations. nature; and almost all wound injuries are sudden, accidental and unpredictable, which requires the application of dressings in the shortest time for treatment, and wait until the cells are cultured before making cell suspensions, which has missed the best time. Timing of treatment

[0012] 3. Some technologies of prior art dressings do not use antibacterial agents, which are easy to breed bacteria during use and cause secondary pollution. The antibacterial agents used in another part of the technology include silver ions, quaternary ammonium salts, etc. Silver ions have certain side effects on the human body, and When the skin is very sensitive, quaternary ammonium salts are likely to cause irritation to the wound, affect the patient's experience of use, and hinder the rapid healing of the wound; and there will be certain side effects after being absorbed by human tissue

[0013] 4. The gels used in the prior art dressings mainly include gelatin and bioactive glass, which are slow to absorb and have insufficient affinity to the skin

[0014] 5. The dressings in the prior art cannot effectively prevent the skin from leaving scars, and skin care products are still needed to dilute the scars after the wound is repaired

[0015] 6. The dressings of the prior art are unsatisfactory for chronic wound repair, and cannot effectively control exudate and repair damaged tissues, blood vessels and nerves

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