Absorbable oral cavity restoration membrane and preparation method thereof

A technology for oral restoration and composite film, applied in the field of absorbable oral adsorption film and its preparation, can solve the problems of patient pain, narrow application range, long chairside time, etc. The effect of postoperative risk

Active Publication Date: 2019-03-26
NEO MODULUS SUZHOU MEDICAL SCI TECH CO LTD
View PDF3 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently used in the repair of oral tissue defects, autologous tissue transplantation is limited, and it will cause additional pain to the patient, and it also has high requirements for the doctor's technical level, and the chair time is longer
ADM (Acellular Dermal Matrix), CM (Collagen Matrix Membrane) and other tissue engineering materials have pr

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] A method for preparing an absorbable oral restoration film, comprising a gelatin fiber film preparation process, a polycaprolactone fiber film preparation process, a composite film pressing process, and a post-treatment process,

[0042] Described gelatin fiber membrane preparation process comprises the steps:

[0043] S1.1, preparation of gelatin solution,

[0044] First, the purified water, acetic acid and butyl acetate were prepared as a dissolving solution. In the prepared dissolving solution, purified water accounted for 35wt%, acetic acid accounted for 25wt%, and ethyl acetate accounted for 40wt%;

[0045] Then, the gelatin and the prepared lysate are prepared as a gelatin solution. In the prepared gelatin solution, the mass ratio of the gelatin to the lysate is 1:8, the gelatin is bovine bone gelatin, and the freezing force range is 160 bloom g;

[0046] Preferably: in step S2.1 of the polycaprolactone fiber film preparation process, the intrinsic viscosity of t...

Embodiment 2

[0065] A method for preparing an absorbable oral restoration film, comprising a gelatin fiber film preparation process, a polycaprolactone fiber film preparation process, a composite film pressing process, and a post-treatment process,

[0066] Described gelatin fiber membrane preparation process comprises the steps:

[0067] S1.1, preparation of gelatin solution,

[0068] First, the purified water, acetic acid and butyl acetate were prepared as a dissolving solution, and the purified water accounted for 40wt% in the prepared dissolving solution, the acetic acid accounted for 30wt%, and the ethyl acetate accounted for 30wt%;

[0069] Then, the gelatin and the prepared dissolving solution are prepared into a gelatin solution, in the prepared gelatin solution, the mass ratio of gelatin to the dissolving solution is 1:6, the gelatin is bovine bone gelatin, and the freezing force range is 200 bloom g;

[0070] Preferably: in step S2.1 of the polycaprolactone fiber film preparatio...

Embodiment 3

[0089] A method for preparing an absorbable oral restoration film, comprising a gelatin fiber film preparation process, a polycaprolactone fiber film preparation process, a composite film pressing process, and a post-treatment process,

[0090] Described gelatin fiber membrane preparation process comprises the steps:

[0091] S1.1, preparation of gelatin solution,

[0092] First, the purified water, acetic acid and butyl acetate were prepared as a dissolving solution. In the prepared dissolving solution, purified water accounted for 38wt%, acetic acid accounted for 28wt%, and ethyl acetate accounted for 35wt%;

[0093] Then, the gelatin and the prepared lysate are prepared as a gelatin solution. In the prepared gelatin solution, the mass ratio of the gelatin to the lysate is 1:7, the gelatin is bovine bone gelatin, and the freezing force range is 180 bloom g;

[0094] Preferably: in step S2.1 of the polycaprolactone fiber film preparation process, the intrinsic viscosity rang...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Intrinsic viscosityaaaaaaaaaa
Fiber diameteraaaaaaaaaa
Diameteraaaaaaaaaa
Login to view more

Abstract

The invention discloses an oral cavity restoration membrane and a preparation method thereof. The oral cavity restoration membrane uses gelatin and polycaprolactone as raw materials, which are subjected to a static spinning process respectively for obtaining a membrane formed by nanometer stage fiber; the lamination is performed in sequence of a gelatin layer, a polycaprolactone layer and a gelatin layer to obtain the three-layer structure oral cavity restoration membrane with the gradually changed fiber diameter. The preparation method of the oral cavity restoration membrane comprises the following steps of preparing a gelatin solution, preparing a gelatin membrane, drying the gelatin membrane, preparing a polycaprolactone solution, preparing a polycaprolactone membrane, drying the polycaprolactone membrane, laminating the gelatin fiber membrane and the polycaprolactone fiber membrane, and performing cutting, inner packaging, sterilization and outer packaging. The method has the advantages that the keratinized gum growth can be effectively guided; the restoration time is shortened; the membrane is applied to the oral cavity and maxillofacial soft tissue restoration in a wider range.

Description

technical field [0001] The invention belongs to the technical field of biological materials and tissue engineering, and in particular relates to an absorbable oral cavity adsorption film and a preparation method thereof. Background technique [0002] Oral tissue defects need to be repaired. At present, oral tissue defects mainly include loss of periodontal tissue, insufficient or missing width of attached gingiva, defect after maxillofacial tumor resection, wound dehiscence after GBR, and donor site defect of connective tissue transplantation. , maxillary sinus fistula, wound closure after mandibular impacted tooth extraction, gingival recession, root surface exposure, abnormal frenulum attachment position / vestibular groove too shallow, buccal mucosal tissue defect, and prevention of gustatory sweating syndrome, etc. [0003] At present, in the repair of oral tissue defects, autologous tissue transplantation is limited, and it will cause additional pain to the patient. It al...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61L27/40A61L27/22A61L27/58A61L27/18D04H1/30D04H1/435D04H1/728
CPCA61L27/18A61L27/222A61L27/58D04H1/30D04H1/435D04H1/728C08L67/04
Inventor 靳柯张阳
Owner NEO MODULUS SUZHOU MEDICAL SCI TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap