Preparation method of hemostatic menstruation-regulating granules

Abstract

The invention relates to a preparation method of hemostatic menstruation-regulating granules. The preparation method comprises the following steps of: preparing materials according to a prescription of the hemostatic menstruation-regulating granules; mixing radix angelicae sinensis and fructus citri sarcodactylis; then, performing extraction by a distillation method; collecting volatile oil to obtain a mixed extraction solution and mixed medicine residues of the radix angelicae sinensis and the fructus citri sarcodactylis; performing inclusion on the volatile oil by beta-cyclodextrin to obtaina beta-cyclodextrin inclusion compound; crushing colla corii asini into colla corii asini powder; taking and crushing a half amount of radix astragali to respectively obtain ultrafine radix astragalipowder and coarse radix astragali powder; mixing the coarse radix astragali powder, the other half amount of radix astragali, the mixed medicine residues of the radix angelicae sinensis and the fructus citri sarcodactylis, radix codonopsis, radix paeoniae alba, herba agrimoniae, radix rubiae and radix dipsaci; performing water extraction, filtration and impurity removal to obtain a water extraction solution; then, merging the obtained water extraction solution with the mixed extraction solution of the radix angelicae sinensis and the fructus citri sarcodactylis; performing concentration to obtain an extract with the specific gravity being 1.25 to 1.35; performing vacuum drying treatment and crushing on the extract to obtain dry extract powder; uniformly mixing the dry extract powder, thecolla corii asini powder, the ultrafine radix astragali powder and auxiliary materials, and performing dry process granulation; and then, performing blending with the beta-cyclodextrin inclusion compound to obtain the hemostatic menstruation-regulating granules.

Description

technical field

[0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a preparation method of Zhixue Tiaojing Granules. Background technique

[0002] Zhixue Tiaojing granules are mainly prepared from nine medicinal materials such as donkey-hide gelatin, angelica, bergamot, astragalus, codonopsis pilosula, and white peony. See expired menstrual blood, pale menstruation, mental fatigue, dizziness, lower abdominal distension, pale tongue, thin white fur, thready and weak pulse.

[0003] At present, wet granulation and one-step granulation are mainly used in the preparation of Zhixue Tiaojing Granules. Among them, in the wet granulation process, the traditional Chinese medicine extract is concentrated into an extract with a relative density of about 1.1, and then spray-dried to obtain a dry cream powder, and then add donkey-hide gelatin powder, astragalus ultrafine powder and appropriate amount of auxiliary materials ...

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