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Jerusalem artichoke meal inulin capable of improving functional dyspepsia and preparation method and application thereof

An indigestion, functional technology, applied in the application, digestive system, function of food ingredients, etc., can solve problems such as the treatment of functional indigestion with Jerusalem artichoke inulin, and achieve the goal of promoting industrial output value, lowering extraction temperature, and reducing energy consumption. Effect

Active Publication Date: 2020-03-24
CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, so far, there is no report on the treatment of functional dyspepsia with Jerusalem artichoke inulin

Method used

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  • Jerusalem artichoke meal inulin capable of improving functional dyspepsia and preparation method and application thereof
  • Jerusalem artichoke meal inulin capable of improving functional dyspepsia and preparation method and application thereof
  • Jerusalem artichoke meal inulin capable of improving functional dyspepsia and preparation method and application thereof

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preparation example Construction

[0035] The present invention provides a method for preparing Jerusalem artichoke meal inulin for improving functional dyspepsia, comprising the following steps:

[0036] 1) mixing Jerusalem artichoke meal powder with a buffer solution containing glycosidase, enzymolysis and extraction to obtain an extract;

[0037] 2) removing protein and pectin macromolecular impurities from the extract by ultrafiltration to obtain a crude extract of Jerusalem artichoke meal inulin;

[0038] 3) Desalting and purifying the crude Jerusalem artichoke meal inulin extract to obtain a desalted Jerusalem artichoke meal inulin extract;

[0039] 4) The desalted Jerusalem artichoke meal inulin extract is subjected to secondary ultrafiltration to remove monosaccharide and oligosaccharide small molecule impurities, and dried to obtain Jerusalem artichoke meal inulin.

[0040] The invention mixes the jerusalem meal powder with the buffer solution containing glycosidase, extracts by enzymatic hydrolysis, ...

Embodiment 1

[0061] (1) The Jerusalem artichoke meal produced in the industrial production process of Jerusalem artichoke inulin is crushed by a food crusher (manufacturer: Chengxun Industrial Co., Ltd., model: CXP-DJ-S-5T);

[0062] (2) According to the material-to-liquid ratio of 1:10 (g / mL), add glucosidase (enzyme-to-substrate ratio is respectively pectinase 3U / g, cellulase 5U / g, hemicellulase 10U / g, xylem The ratio of carbohydrase is 5U / g) buffered saline solution (citric acid-sodium citrate buffer, 0.01mol / L, pH 4.0), extract at 45°C for 3h;

[0063] (3) The extract is removed by ultrafiltration to remove macromolecular impurities such as protein and pectin (membrane separation equipment: RNF-0460 type, ultrafiltration membrane molecular weight cut-off 20000Da, membrane area 0.2m 2 , Xiamen Fumei Technology Co., Ltd.; operating pressure difference 1.0Mpa, circulation flow rate 2L / min), to obtain the crude extract of Jerusalem artichoke meal inulin;

[0064] (4) The crude extract of ...

Embodiment 2

[0068] (1) The Jerusalem artichoke meal produced in the industrial production process of Jerusalem artichoke inulin is crushed by a food crusher (manufacturer: Chengxun Industrial Co., Ltd., model: CXP-DJ-S-5T);

[0069] (2) According to the material-to-liquid ratio of 1:30 (g / mL), add glucosidase (enzyme-to-substrate ratio is respectively pectinase 20U / g, cellulase 5U / g, hemicellulase 30U / g, xylem The ratio of carbohydrase is 20U / g) buffered saline solution (citric acid-sodium citrate buffer, 0.5mol / L, pH 5.5), extract at 55°C for 1h;

[0070] (3) The extract is removed by ultrafiltration to remove macromolecular impurities such as protein and pectin (membrane separation equipment: RNF-0460 type, ultrafiltration membrane molecular weight cut-off 20000Da, membrane area 0.2m 2 , Xiamen Fumei Technology Co., Ltd.; operating pressure difference 1.0Mpa, circulation flow rate 2L / min), to obtain the crude extract of Jerusalem artichoke meal inulin;

[0071] (4) The crude extract of...

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Abstract

The invention provides jerusalem artichoke meal inulin capable of improving functional dyspepsia and a preparation method and application thereof, belonging to the technical field of deep processing of natural products. The preparation method of the jerusalem artichoke meal inulin comprises the following steps: mixing jerusalem artichoke meal powder with a glycosidase-containing buffer solution, and carrying out enzymolysis extraction; carrying out ultrafiltration on the obtained extract to remove protein and pectin macromolecular impurities; carrying out desalination and purification treatment on the obtained crude extract of the jerusalem artichoke meal inulin; and carrying out secondary ultrafiltration on the desalted jerusalem artichoke meal inulin extract to remove monosaccharide andoligosaccharide small-molecular impurities, and carrying out drying to obtain the jerusalem artichoke meal inulin. Compared with a traditional hot water extraction method, the yield of the jerusalem artichoke meal inulin in the invention is increased. The jerusalem artichoke meal inulin is applied to preparation of medicines for treating functional dyspepsia. Meanwhile, the jerusalem artichoke meal inulin can also be applied to health care products for improving the residual rate of stomach contents, the gastrointestinal hormone level, intestinal flora disorder and / or the oxidative stress level.

Description

technical field [0001] The invention belongs to the technical field of deep processing of natural products, and in particular relates to Jerusalem artichoke meal inulin for improving functional dyspepsia, its preparation method and application. Background technique [0002] Inulin has attracted widespread attention because of its antioxidant activity, and its ability to improve the diversity of intestinal flora, promote intestinal peristalsis, and improve gastrointestinal motility disorders. Over the past 10 years, China's inulin market demand has grown at an average annual growth rate of about 15%. By 2018, China's inulin market demand will be about 8,000 tons, achieving a growth of about 10 times. From a global perspective, the data in 2015 shows that the global market demand for inulin is about 200,000 tons. Among the new global dietary fiber products, new products containing inulin account for about 24%, ranking first. [0003] The production raw materials of inulin are...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08B37/18A61P1/14A23L33/21
CPCA23V2002/00A23L33/21A61P1/14C08B37/0003C08B37/0054A23V2200/3202A23V2250/5062A23L33/22C08L5/00C12P19/04C12P19/14
Inventor 毕宏涛高婷婷魏立新杜玉枝张明杨红霞李岑
Owner CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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