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Methods for controlling the growth of microorganisms and/or biofilms in industrial processes

A biofilm and microbial technology, applied in the direction of adding anti-biological reagents, adding sludge control agents, preventing corrosion/sediment formation of pulping equipment, etc.

Active Publication Date: 2022-07-08
KEMIRA OY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Despite the frequent use of common biocides in circulating water streams, biofilm formation is a common problem in paper and board production

Method used

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  • Methods for controlling the growth of microorganisms and/or biofilms in industrial processes
  • Methods for controlling the growth of microorganisms and/or biofilms in industrial processes
  • Methods for controlling the growth of microorganisms and/or biofilms in industrial processes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] Example 1 (reference)

[0083] Tables 1 and 2 demonstrate the ability of the conventional antimicrobial agent DBNPA to prevent biofilm formation by Meiothermussilvanus and Pseudoxanthomonas taiwanensis. Test conditions were simulated paper or board manufacturing process conditions (synthetic paper machine water, high temperature, presence of fibers, high flow). The conventional antimicrobial DBNPA requires an active compound dose of 1 mg / l to achieve acceptable or significant biofilm reduction efficacy. The results of DBNPA are given in Tables 1 and 2.

[0084] Table 1 shows the effect of DPNPA dose in SPW on the biofilm of Thermus silvanus at 45°C and 150 rpm (high mixing). Biofilms were stained and quantified by absorbance measurements. Dosages are given in active ingredient form.

[0085] Table 1

[0086]

[0087] Table 2 shows the effect of DPNPA dosage in SPW on Pseudoxanthomonas taiwanensis biofilm at 45°C and 150 rpm (high mixing). Biofilms were stained ...

Embodiment 2

[0090] Example 2 (reference)

[0091] Tables 3 and 4 show the effect of the well-known antibiotic gramicidin on biofilm formation of Meiothermussilvanus and Pseudoxanthomonas taiwanensis. In synthetic growth medium R2-broth, gramicidin was able to protect against biological activity at significantly lower concentrations compared to conditions simulating a paper or board production process (synthetic paper machine water, high temperature, presence of fibers, high fluidity). film formation.

[0092] The results in Tables 3 and 4 demonstrate the expected behavior of clinical antibacterial compounds with reduced performance when exposed to non-clinical conditions.

[0093] Table 3 shows the effect of gramicidin doses on Meiothermussilvanus biofilms in R2-broth and SPW. Biofilms were stained and quantified by absorbance measurements. Dosages are given in active ingredient form.

[0094] table 3

[0095]

[0096] Table 4 shows the effect of gramicidin doses on Pseudoxanthomo...

Embodiment 3

[0100] Tables 5 and 6 demonstrate the ability of Compound C and Compound E to prevent biofilm formation by Meiothermus silvanus and Pseudoxanthomonas taiwanensis. The test conditions were the same as those of Example 1. Compound C and Compound E were observed to be able to control biofilms at very low concentrations. The biofilm reduction effect of active compound C or compound E at a dose of 0.2 mg / l has exceeded 90%.

[0101] Table 5 shows the effect of compound C dosage on the biofilm of Thermus rubrum (Meiothermus silvanus) in SPW at 45°C and 150 rpm (high mixing). Biofilms were stained and quantified by absorbance measurements. Compound C doses are given as the active compound.

[0102] table 5

[0103]

[0104] Table 6 shows the effect of Compound E dosage on Meiothermus silvanus biofilm at 45°C and 150 rpm (high mixing). Biofilms were stained and quantified by absorbance measurements. Compound E doses are given as the active compound.

[0105] Table 6

[0106...

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Abstract

The present invention relates to a method for controlling biofilms to remove biofilms formed and / or to control the growth of microorganisms, preferably bacteria, in aqueous environments of industrial production processes comprising cellulosic fibrous material. Applying a compound according to formula I to the aqueous environment of the process, wherein R1, R2 and R3 of formula I independently represent a hydrogen atom; a halogen atom; a hydroxyl group; an amino group; or an amide group having 1 to 10 carbon atoms; and A represents 2-thiazolamine; 2-acrylonitrile; 2-acrylic acid; having 1 to 4 carbon atoms 2-Alkyl or hydroxyalkyl esters of acrylic acid; or -CHCHCONR5R6 groups, wherein R5 and R6 independently represent a hydrogen atom, an alkyl or hydroxyalkyl group having 1 to 4 carbon atoms, provided that a group according to formula I The compound is not 3-[(4-methylphenyl)sulfonyl]-2-acrylonitrile or 4-amino-N-2-thiazolyl-benzene-sulfonamide.

Description

technical field [0001] According to the preambles of the appended independent claims, the present invention relates to a method for controlling the growth of microorganisms and / or biofilms in an industrial process. Background technique [0002] Microorganisms are present in most industrial processes. Their presence is particularly troublesome in water-intensive processes, such as the manufacture of pulp, paper, cardboard, and the like. Microorganisms thrive when the process water contains biodegradable dissolved substances, and the temperature and pH of the process water are conducive to microbial survival. Microorganisms may enter the process through contamination of air, incoming raw water and / or non-sterile raw materials. Without countermeasures, microorganisms can cause widespread problems in processes such as papermaking. Problems associated with microorganisms include, for example, the decomposition of chemical additives, harmful changes in process pH, the formation...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): D21C9/00D21H17/09D21H17/14D21H21/04D21H21/36
CPCD21C9/008D21H17/09D21H17/14D21H21/04D21H21/36
Inventor 亚科·西梅尔马科·科拉里乔纳·康恩
Owner KEMIRA OY
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