Piracetam tablet composition with high drug loading capacity and preparation method thereof

A technology of piracetam tablet and high drug loading, which is applied in the field of pharmaceutical composition and its preparation, which can solve the problems of inconvenient use, difficulty in swallowing, and occurrence of fragments for patients, so as to ensure effectiveness and safety, The operation process is simple and smooth, and the size is suitable for the effect
CN111297818AActive Publication Date: 2020-06-19CHANGZHOU PHARMA FACTORY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
CHANGZHOU PHARMA FACTORY
Publication Date
2020-06-19

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Abstract

The invention provides a piracetam tablet composition with high drug loading capacity and a preparation method thereof. The piracetam tablet composition comprises 80-90% of piracetam, 10-20% of high-formability microcrystalline cellulose (CEOLUSTM), 2-5% of a disintegrating agent, 0.5-2% of a lubricant and 0-4% of a gastric-soluble film coating premix. The composition can effectively improve the drug loading capacity of a piracetam tablet and improve the problem of poor friability of a product due to improvement of the drug loading capacity. In addition, the invention also provides a preparation method for the piracetam tablet with the high drug loading capacity. The method provided by the invention is simple and convenient in process operation, high in production efficiency and applicableto industrial production.
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Description

[0001] Technical field: the present invention relates to a kind of pharmaceutical composition and preparation method thereof, be specifically related to a kind of piracetam tablet composition and preparation method thereof. Background technique:

[0002] Piracetam is a drug for improving brain metabolism, which belongs to the cyclic derivative of r-aminobutyric acid, can promote ATP in the brain, can promote the synthesis of acetylcholine and positively enhance the conduction of nerve excitation, and has the effect of promoting metabolism in the brain. It can resist brain function damage caused by physical and chemical factors, improve retrograde amnesia caused by hypoxia, enhance memory and improve learning ability. It is clinically used to treat senile dementia and is the first-line drug for the treatment of senile dementia.

[0003] Piracetam preparations have been marketed worldwide, and currently there are two dosage forms of injection and oral tablet on the market in Chi...

Claims

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