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33 results about "Product tablet" patented technology

Method for detecting residual quantity of 34 illegally-added medicines in weight-losing health food

The invention relates to the technical field of medicine residue detection. An objective is to provide a method for fast detecting the residual quantity of 34 illegally-added medicines in a weight-losing health food. The method is fast and accurate, and is high in sensitivity and wide in application range. According to the technical scheme, the method comprises: 1) preparing a self-made extractedliquid, which comprises refluxing a mixture of methanol, acetone and octanol polyoxyethylene ether at 60-65 DEG C for 30 min and performing cooling for later use; 2) taking health product tablets, capsules or particles, performing pulverization, accurately weighing 3-10 g of the sample, putting the sample in a centrifuge tube provided with a plug, adding 20-60 mL of a self-made extracted liquid, performing mixing in a vortex oscillator, performing supersonic wave extraction for 2-10 min, performing centrifugation, taking 1 mL of the supernatant out, blow-drying the supernatant, and redissolving the obtained product with 2 mL of 50% of an acetonitrile aqueous solution; and 3) filtering the redissolved solution via a filter membrane with the micropore size being 0.22 mum, and measuring the filtrate via HPLC-MS / MS (that is high performance liquid chromatography and mass spectrum and secondary mass spectrum).
Owner:浙江公正检验中心有限公司 +1

Production method of bee pollen tablet for treating fatty liver

The invention provides a production method of a bee pollen tablet for treating fatty liver, relating to production technologies of product tablets. The production method comprises the following steps of: performing air stream pulverization and wall breaking on impurities-removed bee pollen; soaking in water at normal pressure and temperature; performing ultrasonic treatment; centrifuging by a refrigerated centrifuge with the rotation speed of 8000-10000rpm, taking supernatant; separating the supernatant at the ambient temperature of -5 to 5 DEG C by a molecular sieve of below 2800D to obtain water-soluble bee pollen of which the molecular weight is smaller than 2800D; performing vacuum freeze drying on the water-soluble bee pollen of which the molecular weight is smaller than 2800D to form lybee pollen lyophilized powder with the moisture content below 4%; and mixing the lyophilized powder of bee pollen with water soluble starch and tabletting. According to the production method provided by the invention, the effective components in the bee pollen are extracted by water firstly and then prepared into lyophilized powder, thus being conductive to the subsequent tabletting processing, the tablet is convenient to take, the product activity is kept, and the medicament is not liable to oxidative deterioration and has a good absorption effect and rehydration.
Owner:周斌 +1

Method for detecting residue of 18 illegally-added blood-glucose-reducing and antihypertensive drugs in health product

The invention relates to the technical field of drug residue detection and aims at providing a method for detecting residue of 18 illegally-added blood-glucose-reducing and antihypertensive drugs in ahealth product, which has the characteristics of rapidness, accuracy, simplicity and low cost. According to the technical scheme, the method for detecting the residue of the 18 illegally-added blood-glucose-reducing and antihypertensive drugs in the health product comprises the following steps: (1) preparing homemade extract, namely refluxing a mixture of methyl alcohol, ethyl acetate and decyl alcohol polyoxyethylene ether for 30 minutes at the temperature of 60-65 DEG C, and cooling for later use; (2) taking health product tablets, capsules or granules, breaking, accurately weighing 3-10g of sample, putting into a centrifugal tube provided with a plug, then adding 20-60mL of homemade extract, mixing, carrying out ultrasonic extraction for 2-10 minutes, carrying out centrifugal separation, then taking 1mL of supernatant, carrying out blow drying with nitrogen, and redissolving with 1mL of 50% acetonitrile aqueous solution; and (3) filtering the redissolved solution by virtue of a 0.22 microns microporous membrane, and carrying out HPLC-MS/MS (high performance liquid chromatography+mass spectroscopy+secondary mass spectroscopy detection) determination on filtrate.
Owner:浙江公正检验中心有限公司 +1

Method for detecting residue of 22 illegally-added nerve-calming drugs in health product

The invention relates to a drug residue detection technology and aims at providing a method for detecting residue of 22 illegally-added nerve-calming drugs in a health product, which has the characteristics of rapidness, accuracy, simplicity and low cost. According to the technical scheme, the method for detecting the residue of the 22 illegally-added nerve-calming drugs in the health product comprises the following steps: (1) preparing homemade extract, namely refluxing a mixture of methyl alcohol, ethyl acetate and capryl alcohol polyoxyethylene ether for 30 minutes at the temperature of 60-65 DEG C, and cooling for later use; (2) taking health product tablets, capsules or granules, breaking, accurately weighing 3-10g of sample, putting into a centrifugal tube provided with a plug, thenadding 20-60ml of homemade extract, mixing, carrying out ultrasonic extraction for 2-10 minutes, carrying out centrifugal separation, then taking 1mL of supernatant, carrying out blow drying with nitrogen, and redissolving with 1mL of 50% methanol aqueous solution; and (3) filtering the redissolved solution by virtue of a 0.22 micron microporous membrane, and carrying out HPLC-MS/MS (high performance liquid chromatography+mass spectroscopy+secondary mass spectroscopy detection) determination on filtrate.
Owner:浙江公正检验中心有限公司 +1

Compound sodium fructose diphosphate and fructose orally disintegrating tablets and preparation method thereof

The invention provides compound sodium fructose diphosphate and fructose orally disintegrating tablets. The compound sodium fructose diphosphate and fructose orally disintegrating tablets are prepared from the following ingredients in percentage by weight: 10-60% of sodium fructose diphosphate, 5-30% of fructose, 5-30% of sublimable substance, 0.5-3% of a surfactant, 4-20% of a disintegrating agent, 0.5-3.0% of a flow aid, 0.5-3.0% of a lubricant, 20.0-58% of a diluent, 0.2-2% of a corrigent, and 3-8% of a coating material. The invention further provides a preparation method of the compound sodium fructose diphosphate and fructose orally disintegrating tablets. The preparation method comprises the following steps: mixing the active ingredients, namely sodium fructose diphosphate and fructose, and pharmaceutical excipients, wherein the sublimable substance is added into the pharmaceutical excipients, tabletting the mixture, coating the obtained semi-finished product tablets, heating the semi-finished product tablets after coating, and drying, thus the sublimable substance sublimates, a plurality of holes are formed in the tablets, and finally, the tablets capable of rapidly disintegrating and with certain strength are obtained. The orally disintegrating tablets can rapidly disintegrate, so that good clinical effects can be obtained; the preparation method is easy and convenient to operate, is suitable for industrial production, and has a large application value.
Owner:SHANGHAI SUNTECH PHARMA +1

Preparing device for migraine treatment medicine

The invention discloses a preparing device for migraine treatment medicine. The preparing device comprises a fixed machine frame, a feeding opening extending upwards is fixedly formed in the upper endface of the fixed machine frame, a cylindrical screening net is fixedly arranged on the right side of the feeding opening, an inverted-conical discharging cavity is communicated to the lower side ofthe screening net, a delivering pipe is arranged in the middle of the right end face of the discharging cavity, a liquid cavity is fixedly formed in the upper end of the delivering pipe, a transmission cavity is communicated to the lower end face of the discharging cavity, a horizontal rotating disc is arranged in the transmission cavity, through holes are circumferentially formed in the rotatingdisc, a horizontal conveying belt is arranged on the lower side of the left end face of the fixed machine frame, and containing bottles are arranged in the conveying belt. When the preparing device works, the device is simple in structure and easy to operate, two intermittent movement parts simultaneously rotate to cooperatively complete the operation process of medicine powder pelleting, the automatic efficiency of the device is improved, unaccepted products in finished-product tablets are reduced through the tablet screening net, and waste of medicine is reduced.
Owner:NINGBO HANGZHOU BAY NEW DISTRICT NO 9 TECH SERVICE

Micro-powder encapsulating and material mixing device for improving content uniformity of clonidine hydrochloride in zhenju antihypertensive tablets and material mixing method

The invention discloses a micro-powder encapsulating and material mixing device for improving the content uniformity of clonidine hydrochloride in zhenju antihypertensive tablets and a material mixingmethod. The material mixing method comprises the following steps: firstly, a clonidine hydrochloride solution is prepared by dissolving clonidine hydrochlorid with an ethanol solution, and is uniformly sprayed to a medicine mixing container containing other auxiliary materials while rotating at high speed in a dosing nozzle, furthermore, a transverse cutting blade and a longitudinal cutting bladeopposite to the dosing nozzle in the rotation direction are arranged in the medicine mixing container, and the medicine mixing container synchronously rotates at the high speed reversely while the materials are mixed until the solution is completely sprayed, the ethanol solution is volatilized in the high-speed rotating container, and the clonidine hydrochloride and the other raw materials form amicro-powder encapsulating state to complete the micro-powder encapsulating and material mixing process; and the micro-powder encapsulating and material mixing device for improving the content uniformity of the clonidine hydrochloride in the zhenju antihypertensive tablets and the material mixing method disclosed by the invention effectively improve the mixing uniformity and the bonding firmnessdegree of the clonidine hydrochloride, enhance the content uniformity of the clonidine hydrochloride in finished product tablets of the zhenju antihypertensive tablets, lower errors in the proceduresof artificial compounding, material mixing and the like, reduce the workload and improve the work efficiency.
Owner:ZHONGXING PHARM CO LTD JIANGSU

Production method of pine pollen tablet for treating prostatic hypertrophy

ActiveCN102114056ALow costSignificant effect on hypertrophyUrinary disorderPill deliveryEccentric hypertrophySide effect
The invention provides a production method of a pine pollen tablet for treating prostatic hypertrophy, relating to production technologies of product tablets. The production method comprises the following steps of: performing air stream pulverization and wall breaking on pine pollen with impurities removed; soaking in water of normal pressure and temperature; performing ultrasonic treatment; centrifuging by a refrigerated centrifuge, taking supernatant; separating the supernatant at the ambient temperature of 1-5 DEG C to obtain water soluble matters of pine pollen of which the molecular weight is smaller than 2000D; performing vacuum freeze drying on the water soluble matters of pine pollen of which the molecular weight is smaller than 2000D to form lyophilized powder of pine pollen with the moisture content below 5%; and finally, mixing the lyophilized powder of pine pollen with lecithin, water-soluble starch and microcrystalline cellulose PH102 for preparation. The pine pollen tablet provided by the invention has no side effect, simple production process and low cost, is favorable for reducing the medicament cost and reserving the activity of functional substances, is not liable to oxidative deterioration, and has good absorption effect and good rehydration.
Owner:YANTAI NEW ERA HEALTH IND +1

Detection method of 22 kinds of illegally added sedative drugs residues in health products

The invention relates to a drug residue detection technology and aims at providing a method for detecting residue of 22 illegally-added nerve-calming drugs in a health product, which has the characteristics of rapidness, accuracy, simplicity and low cost. According to the technical scheme, the method for detecting the residue of the 22 illegally-added nerve-calming drugs in the health product comprises the following steps: (1) preparing homemade extract, namely refluxing a mixture of methyl alcohol, ethyl acetate and capryl alcohol polyoxyethylene ether for 30 minutes at the temperature of 60-65 DEG C, and cooling for later use; (2) taking health product tablets, capsules or granules, breaking, accurately weighing 3-10g of sample, putting into a centrifugal tube provided with a plug, thenadding 20-60ml of homemade extract, mixing, carrying out ultrasonic extraction for 2-10 minutes, carrying out centrifugal separation, then taking 1mL of supernatant, carrying out blow drying with nitrogen, and redissolving with 1mL of 50% methanol aqueous solution; and (3) filtering the redissolved solution by virtue of a 0.22 micron microporous membrane, and carrying out HPLC-MS / MS (high performance liquid chromatography+mass spectroscopy+secondary mass spectroscopy detection) determination on filtrate.
Owner:浙江公正检验中心有限公司 +1

Continuous ring-pull can cutting and tabletting production process

PendingCN112872721ASolve the problem that cutting cannot realize automatic feedingSolve processabilityOther manufacturing equipments/toolsTabletingIndustrial engineering
The invention relates to a continuous ring-pull can cutting and tabletting production process which comprises the following steps: a ring-pull can transfer procedure, wherein ring-pull cans output by a storage bin are clamped and stopped on a material turning plate; a ring-pull can feeding procedure, wherein a pushing assembly enables the clamped ring-pull cans to fall onto a supporting assembly; a ring-pull can supporting procedure, wherein the supporting assembly is pressed downwards to fix and support the ring-pull cans; a ring-pull can cutting procedure, wherein end openings in two sides of the ring-pull cans are cut by a cutting mechanism; a ring-pull can transverse cutting procedure, wherein the ring-pull cans are transversely cut and crevassed through a transverse cutting assembly; a first-stage flattening procedure, wherein a driving assembly drives a pressing roller to conduct first-stage flattening on the ring-pull cans; a primary tablet transferring procedure, wherein tablets subjected to primary flattening are transferred to a demising groove; a second-stage flattening procedure, wherein the tablets on the demising groove enter a roller press so as to be subjected to second-stage flattening; and a finished product tablet output procedure, wherein the finished product tablets subjected to second-stage flattening are output into a finished product tablet collecting box. According to the continuous ring-pull can cutting and tabletting production process provided by the invention, the automation degree is high, continuous automatic processing is achieved, and secondary recycling of the ring-pull cans is facilitated through finished product tabletting.
Owner:王一晓

A kind of compound fructose diphosphate sodium fructose orally disintegrating tablet and preparation method thereof

The invention provides compound sodium fructose diphosphate and fructose orally disintegrating tablets. The compound sodium fructose diphosphate and fructose orally disintegrating tablets are prepared from the following ingredients in percentage by weight: 10-60% of sodium fructose diphosphate, 5-30% of fructose, 5-30% of sublimable substance, 0.5-3% of a surfactant, 4-20% of a disintegrating agent, 0.5-3.0% of a flow aid, 0.5-3.0% of a lubricant, 20.0-58% of a diluent, 0.2-2% of a corrigent, and 3-8% of a coating material. The invention further provides a preparation method of the compound sodium fructose diphosphate and fructose orally disintegrating tablets. The preparation method comprises the following steps: mixing the active ingredients, namely sodium fructose diphosphate and fructose, and pharmaceutical excipients, wherein the sublimable substance is added into the pharmaceutical excipients, tabletting the mixture, coating the obtained semi-finished product tablets, heating the semi-finished product tablets after coating, and drying, thus the sublimable substance sublimates, a plurality of holes are formed in the tablets, and finally, the tablets capable of rapidly disintegrating and with certain strength are obtained. The orally disintegrating tablets can rapidly disintegrate, so that good clinical effects can be obtained; the preparation method is easy and convenient to operate, is suitable for industrial production, and has a large application value.
Owner:SHANGHAI SUNTECH PHARMA +1

Detection method of 18 kinds of illegally added hypoglycemic and antihypertensive drug residues in health products

The invention relates to the technical field of drug residue detection and aims at providing a method for detecting residue of 18 illegally-added blood-glucose-reducing and antihypertensive drugs in ahealth product, which has the characteristics of rapidness, accuracy, simplicity and low cost. According to the technical scheme, the method for detecting the residue of the 18 illegally-added blood-glucose-reducing and antihypertensive drugs in the health product comprises the following steps: (1) preparing homemade extract, namely refluxing a mixture of methyl alcohol, ethyl acetate and decyl alcohol polyoxyethylene ether for 30 minutes at the temperature of 60-65 DEG C, and cooling for later use; (2) taking health product tablets, capsules or granules, breaking, accurately weighing 3-10g of sample, putting into a centrifugal tube provided with a plug, then adding 20-60mL of homemade extract, mixing, carrying out ultrasonic extraction for 2-10 minutes, carrying out centrifugal separation, then taking 1mL of supernatant, carrying out blow drying with nitrogen, and redissolving with 1mL of 50% acetonitrile aqueous solution; and (3) filtering the redissolved solution by virtue of a 0.22 microns microporous membrane, and carrying out HPLC-MS / MS (high performance liquid chromatography+mass spectroscopy+secondary mass spectroscopy detection) determination on filtrate.
Owner:浙江公正检验中心有限公司 +1
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