Etamsylate gel patch and preparation method thereof

A technology of acetamine gel patch and acetamine, which is applied in the direction of pharmaceutical formulas, medical preparations with no active ingredients, medical preparations containing active ingredients, etc., can solve the problem of not being able to give priority to guaranteeing Stability, not suitable for daily drug administration, can not be exposed at any time, etc., to achieve the effect of reducing systemic adverse reactions, reducing systemic adverse reactions, and not easy to stain clothes
CN111773201APending Publication Date: 2020-10-16YANGZHOU ZHONGBAO PHARMA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
YANGZHOU ZHONGBAO PHARMA
Publication Date
2020-10-16

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Abstract

The invention relates to the technical field of medicine, and discloses an etamsylate gel patch and a preparation method thereof. The etamsylate gel patch is composed of a backing layer, an adhesive layer, a gel layer and an anti-adhesive layer in sequence, wherein the gel layer comprises a gel substrate and a medicine active ingredient etamsylate. Adhesion tests, in-vitro dissolution tests and in-vitro skin penetration tests prove that the etamsylate gel patch has good adhesion performance, can be used repeatedly, can effectively release medicines through the skin, and can be stopped administrating at any time as needed to reduce systemic adverse reactions, and is safe and reliable.
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Description

technical field

[0001] The invention relates to the field of pharmacy, in particular to a phensulfame gel patch and a preparation method thereof. Background technique

[0002] Etamsylate (English name Etamsylate), is clinically used to prevent and treat bleeding before and after various operations, and can also be used for bleeding caused by platelet dysfunction and increased vascular fragility. It was first patented by Lab.OM in the UK in 1962 And it was approved. In 1981, Wuhan Wu Pharmaceutical Co., Ltd. applied for and was approved for listing in my country. Currently, tablets, injection powder injections, injections, sodium chloride injections and glucose injections are on the market in China. [1] , to control post-operative bleeding, oral or intramuscular or intravenous injection of 250-500 mg dose, repeated every 4-6 hours if necessary, adverse reactions include nausea, headache, rash, temporary hypotension, etc., occasionally intravenous Anaphylactic shock has been r...

Claims

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