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Composition with repairing and soothing effects as well as preparation and application thereof

A composition and action technology, which can be used in skin care preparations, medical preparations containing active ingredients, drug combinations, etc. Accelerates self-repair often, has anti-inflammatory and soothing effects, and promotes proliferation and differentiation.

Pending Publication Date: 2021-02-12
广州澳梓美生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The cell membrane is impermeable to most bioactive substances, especially macromolecular bioactive substances. Therefore, when functional cosmetics containing biomacromolecules are applied to the skin, it is difficult for the active ingredients to penetrate into the cells, so it is difficult to exert their functions. effect
In order to make the active substances play an effective role, the usual practice is to increase the amount of active substances added, but this often brings other risks, such as increased product costs, product irritation, stability issues, waste of raw materials, etc.

Method used

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  • Composition with repairing and soothing effects as well as preparation and application thereof
  • Composition with repairing and soothing effects as well as preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A composition with repairing and soothing effects, comprising the following components by mass fraction: Aloe vera extract 10%, soluble proteoglycan 3%, inositol 2%, bisabolol 1%, lecithin 2%, Sucrose multistearate 3%, cetyl palmitate 3%, palmitic acid 5%, glycerin 20%, methyl propylene glycol 20%, the balance is deionized water.

[0029] A preparation method of a composition having a repairing and soothing effect, comprising the following steps:

[0030] Step 1: Heat deionized water to 85°C, add inositol: 2%, stir to dissolve completely, then cool down to 45°C, add Aloe vera extract: 10%, soluble proteoglycan: 3%, and stir evenly Obtain the mixed solution for subsequent use;

[0031] Step 2: Heat cetyl palmitate: 3%, palmitic acid: 5%, and bisabolol: 1% to 75°C, stir to completely dissolve each component, and obtain a mixed solution to keep warm for later use;

[0032] Step 3: Add lecithin: 2%, sucrose multistearate: 3%, glycerin: 20%, methylpropanediol: 20% into the...

Embodiment 2

[0035] A composition with repairing and soothing effects, comprising the following components by mass fraction: Aloe vera extract 15%, soluble proteoglycan 5%, inositol 1%, bisabolol 2%, lecithin 3%, Sucrose multistearate 4%, cetyl palmitate 3%, palmitic acid 5%, glycerin 30%, methyl propylene glycol 20%, the balance is deionized water.

[0036] A preparation method of a composition having a repairing and soothing effect, comprising the following steps:

[0037] Step 1: Heat deionized water to 85°C, add inositol: 1%, stir to dissolve completely, then cool down to 45°C, add Aloe vera extract: 15%, soluble proteoglycan: 5%, and stir evenly Obtain the mixed solution for subsequent use;

[0038] Step 2: Heat cetyl palmitate: 3%, palmitic acid: 5%, and bisabolol: 2% to 75-80°C, stir to completely dissolve each component, and obtain a mixed solution to keep warm for later use;

[0039] Step 3: Add lecithin: 3%, sucrose multistearate: 4%, glycerin: 30%, methylpropanediol: 20% into ...

Embodiment 3

[0042]A composition with repairing and soothing effects, comprising the following components by mass fraction: 20% Aloe Vera extract, 5% soluble proteoglycan, 2% inositol, 2% bisabolol, 5% lecithin, Sucrose multistearate 5%, cetyl palmitate 4%, palmitic acid 5%, glycerin 25%, methyl propylene glycol 25%, and the balance is deionized water.

[0043] A preparation method of a composition having a repairing and soothing effect, comprising the following steps:

[0044] Step 1: Heat deionized water to 85°C, add inositol: 2%, stir to dissolve completely, then cool down to 45°C, add Aloe vera extract: 20%, soluble proteoglycan: 5%, and stir evenly Obtain the mixed solution for subsequent use;

[0045] Step 2: Heat cetyl palmitate: 4%, palmitic acid: 5%, bisabolol: 2% to 75°C, stir to completely dissolve each component, and obtain a mixed solution to keep warm for later use;

[0046] Step 3: Add lecithin: 5%, sucrose multistearate: 5%, glycerin: 25%, methylpropanediol: 25% into the ...

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Abstract

The invention belongs to the field of cosmetics, and provides a composition with repairing and soothing effects. The composition is characterized by comprising the following components in percentage by mass: 5-20 percent of an aloe vera extract, 1-5 percent of soluble proteoglycan, 0.1-2 percent of inositol, 0.1-3 percent of myrrh alcohol, 1-5 percent of lecithin, 1-5 percent of sucrose polystearate, 1-5 percent of cetyl palmitate, 1-5 percent of palmitic acid, 30-50 percent of polyhydric alcohol and the balance being deionized water. The polyol is one or a composition of two of glycerol, 1,2-propylene glycol, 1,3-propylene glycol, butanediol, dipropylene glycol and methyl propylene glycol. The composition provided by the invention can inhibit the expression level of cytokines in inflammatory response, reduce the damage of skin inflammatory response to the composition, promote keratinocyte proliferation and differentiation after inflammatory response and promote the generation of collagen and hyaluronic acid; meanwhile, the absorption of active matters can be improved, so that the addition amount of the active matters is reduced, and the irritation of the formula is reduced.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a composition with repairing and soothing effects and its preparation and application. Background technique [0002] Aloe vera has very important medicinal value. It is rich in a variety of biologically active ingredients, mainly sugars, amino acids, vitamins, minerals, organic acid active enzymes, aloe-emodin, aloin, aloe diced, etc. Among them, aloe polysaccharide is the main active ingredient, which can promote wound healing and tissue repair, anti-inflammatory and antibacterial effects. Aloe polysaccharide can promote the expression of epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) in the process of tissue repair, thereby improving the self-repair ability of damaged tissue. At the same time, aloe polysaccharides can also regulate the level of inflammatory factors in the body's self-healing process, avoiding excessive inflammatory reacti...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/34A61K8/36A61K8/37A61K8/55A61K8/73A61K8/60A61K8/14A61Q19/00A61P29/00
CPCA61K8/9794A61K8/14A61K8/553A61K8/37A61K8/73A61K8/361A61K8/34A61K8/345A61K8/60A61Q19/00A61P29/00A61K2800/10A61K2800/5922
Inventor 陈丽红方永生
Owner 广州澳梓美生物科技有限公司
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