The present application relates to the technical field of
medicine, and provides application of Ben Dung decoction in preparation of
medicine for treating
ovarian cancer, wherein the Ben Dung decoction is prepared from licorice, Szechuan lovage
rhizome, Chinese angelica,
pinellia, radix scrophulariae, radix puerariae, radix paeoniae, ginger and root white
bark of
prunus mira koehne with a
mass ratio of (1.5-2.5):(1.5-2.5):(1.5-2.5):(3-5):(1-3):(6-10):(1.5-2.5):(3-5):(4-7). The Ben Dung decoction can significantly affect the morphology and cycle of
ovarian cancer ES-2 and OV-1063 cells, effectively inhibit the malignant phenotypes such as proliferation, migration, infiltration and
cloning of the
ovarian cancer ES-2 and OV-1063 cells, and inhibit the expression level of CA125 and CEA proteins in the ovarian
cancer OV-1063 cells.