Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Palladium ion probe and preparation method and application thereof

A palladium ion probe and ion technology, which is applied in the field of ratiometric palladium ion fluorescent probe and its preparation, can solve the problems of complicated operation and low accuracy, and achieve the effects of high sensitivity, high selectivity and superior sensitivity

Active Publication Date: 2021-05-07
SHENZHEN INST OF ADVANCED TECH
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the problems of complex operation and low accuracy in current palladium ion detection methods, the present invention designs and develops a highly sensitive and highly selective photoacoustic ratio palladium ion probe

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Palladium ion probe and preparation method and application thereof
  • Palladium ion probe and preparation method and application thereof
  • Palladium ion probe and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1: the preparation of compound 1

[0041] This embodiment is also prepared by a one-step method, and is prepared according to the following route:

[0042]

[0043]The specific process is: add 1 mmol of Cy7-Cl, bis(2-picoline) amine and triethylamine according to the molar ratio of 1:1:1 to 10 ml and fully react in the organic solvent DMF for 4 hours, the reaction temperature is 40 °C, During the reaction, the color of the solution changed from green to blue. After the reaction was completed, the reaction system was cooled to room temperature, extracted with dichloromethane and water at a volume ratio of 1:10, extracted with 20ml of dichloromethane and 200ml of water, and extracted After layering, the dichloromethane layer was dried with 1 g of anhydrous magnesium sulfate, and after drying, the solvent was removed by rotary evaporation to obtain about 0.4 g of a blue product, namely compound 1.

Embodiment 2

[0044] Example 2: Identification of Compound 1

[0045] Carry out NMR analysis to the blue compound 1 prepared in Example 1, the NMR model is Bruker AVANCE400, the test condition is room temperature, and the NMR data is:

[0046] 1H NMR (400MHz, CDCl3) δ8.72 (d, J = 4.5Hz, 2H), 7.85 (t, J = 6.5Hz, 2H), 7.67 (d, J = 13.5Hz, 2H), 7.40 (dd, J =7.1,5.2Hz,2H),7.32(m,J=7.5Hz,6H),7.15(t,J=7.4Hz,2H),7.00(d,J=7.9Hz,2H),5.90(d,J =13.6Hz, 2H), 4.74(s, 4H), 4.01(q, J=7.1Hz, 4H), 2.60(t, J=6.4Hz, 4H), 1.94(dd, J=12.7, 6.5Hz, 2H ),1.45(s,12H),1.38(t,J=7.2Hz,6H).13C NMR(101MHz,CDCl3)δ173.41,169.06,156.29,149.72,143.67,142.14,140.47,138.19,128.56,124.66,124.28, 123.66, 123.43, 122.19, 109.39, 96.90, 59.97, 48.26, 38.78, 29.69, 28.62, 25.07, 21.95, 11.90.

[0047] The blue compound 1 prepared in Example 1 was subjected to simple analysis. The equipment model of the mass spectrometer was Orbitrap Fusion Tribrid mass spectrometer, and the test condition was room temperature. The high-resoluti...

Embodiment 3

[0048] Example 3: Compound 1 to Pd 2+ selectivity.

[0049] In 0.5% dimethyl sulfoxide (DMSO) pure water, 1.0 equivalent of different metal cations (Pd 2+ , Ca 2+ ,Cd 2+ ,Co 2+ ,Cr 2+ ,Cs + ,Cu 2+ , Fe 2+ , Fe 3+ ,Ir 3+ ,Mg 2+ ,Mn 2+ , Ni 2+ ,Pb 2+ ,Pt 2+ , Re + , Rh 3+ ,Zn 2+ ). Depend on figure 1 It can be seen that when 1.0 equivalent of Pd is added to the compound 1 solution 2+ Finally, the absorption of compound 1 at 710nm disappeared completely, and a new absorption peak appeared at 770nm at the same time, while other metal ions had little effect on the absorption of compound 1.

[0050] At the same time, the visual change of the solution color is: when adding Pd 2+ After that, the solution changed from blue to green, and when other metal ions were added, the color of the solution remained almost unchanged.

[0051] Secondly, the effect of metal ions on the fluorescence of the solution was tested. Add 1.0 equivalent of Pd to compound 1 solution (25...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a palladium ion probe and a preparation method and application thereof. Specifically, Cy7-Cl, bis (2-methylpyridine) amine and triethylamine fully react in an organic solvent, and the color of the solution is changed from green to blue during the reaction; and after the reaction is finished, a product is extracted by using dichloromethane and water, a dichloromethane layer is dried, and rotary evaporation is carried out to obtain a blue product, namely the palladium ion probe. The prepared palladium ion probe belongs to a ratio type palladium ion probe, and has anti-interference performance and high detection precision. The palladium ion probe can be used for detecting trace or even trace palladium ions in the environment and organisms.

Description

technical field [0001] The invention belongs to the technical field of molecular probes, relates to a palladium ion probe and its preparation and application, more specifically relates to a ratio-type palladium ion fluorescent probe and its preparation method and application. Background technique [0002] Heavy metals play an important role in physics, chemistry, and environmental sciences, among which palladium metal has been widely used in various industries due to its special physical and chemical properties. However, the excessive use of palladium will inevitably cause its residues in the environment, causing environmental heavy metal pollution and people's health problems. Therefore, the detection of palladium ions is particularly important. The researchers found that the maximum daily intake of healthy people should be less than 15 μg. In the pharmaceutical industry, the residual amount of palladium in medicines is regulated at 5-10 mg / kg. The discharge of a large a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C09K11/06C07D401/14G01N21/17G01N21/31G01N21/64G01N21/79G01N31/16A61K49/00
CPCC09K11/06C07D401/14G01N21/643G01N21/31G01N21/79G01N21/1702G01N31/16A61K49/22C09K2211/1007C09K2211/1029G01N2021/6421
Inventor 蔡林涛刘闯军向晶晶周理华龚萍
Owner SHENZHEN INST OF ADVANCED TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com