Synthesis method of 9,10-anthracenedicarboxylic acid

Abstract

The invention relates to an anthracene compound, and in particular, relates to a synthesis method of 9,10-anthracenedicarboxylic acid, wherein the synthesis method comprises the steps: dissolving anthracene in a hydrogen bromide solution and an acetic acid solution, then adding trioxymethylene and N,N,N-trimethyl-1-tetradecyl ammonium bromide, and reacting under the protection of N2 to obtain a first intermediate; then dissolving the first intermediate in dimethyl sulfoxide, dropwise adding a mixed solution of a sodium ethoxide solution and 2-nitropropane, filtering, and performing chromatographic separation to obtain a second intermediate; and adding a mixed solvent, sulfamic acid and sodium chlorite into the second intermediate to react, adding an ammonium chloride solution after the reaction is finished, and then extracting, drying and filtering to obtain a 9,10-anthracenedicarboxylic acid solid. The method can accurately position the ninth and tenth positions of anthracene, and has the advantages of strong positioning effect, few reaction byproducts, easy separation of target products, and high yield.

Description

technical field [0001] The present invention relates to a synthesis method of anthracene compound, more specifically, it relates to a synthesis method of 9,10-anthracene dicarboxylic acid. Background technique [0002] Anthracene, also called scintillation crystal, the centers of the three rings of anthracene are on a straight line, and anthracene is a colorless flaky crystal; the chemical activity of the 9 and 10 positions in the anthracene molecule is relatively high. [0003] 9,10-Anthracene dicarboxylic acid is a fused ring aromatic acid, which is a common organic ligand. Among the existing synthetic methods, the method of using n-butyllithium is the most mature method, which mainly uses anthracene as raw material, and through bromine Synthesis of bromoanthracene, and reaction with carbon dioxide under the catalysis of butyllithium to obtain the target product 9,10-anthracene dicarboxylic acid. However, in the existing methods, the synthesis of 9,10-anthracenedicarboxyl...

AI Technical Summary

Problems solved by technology

However, in the existing methods, the synthesis of 9,10-anthracene dicarboxylic acid still has problems such as cumbersome synthetic routes and low yields.

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