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Antioxidant composition as well as application and product thereof

An anti-oxidation and composition technology, applied in the field of skin care products, can solve problems such as oxidative stress, lipid peroxidation, and induced aging, and achieve soothing effects and significant anti-oxidation effects

Active Publication Date: 2021-09-24
HUNAN YUJIA COSMETICS MFG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But sometimes because of external influences, endogenous diseases, etc., this balance will be broken, causing damage to the skin
Usually, such oxidizing substances include active oxygen, active nitrogen, hydroxyl radicals, superoxide anions, singlet oxygen, hydrogen peroxide, hypochlorous acid, ozone, etc., through electron transfer, free radical addition reactions, etc. , resulting in many problems such as oxidative stress and lipid peroxidation
[0004] Furthermore, the active oxygen and free radicals brought about by the imbalance of redox state of the skin will not only induce aging, but also cause other skin problems

Method used

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  • Antioxidant composition as well as application and product thereof
  • Antioxidant composition as well as application and product thereof
  • Antioxidant composition as well as application and product thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～3 and comparative example 1～2

[0041] The compositions of Examples 1-3 and Comparative Examples 1-2 are shown in Table 1, and Examples 1-3 are antioxidant compositions of the present invention.

[0042] Table 1

[0043] components Comparative example 1 Example 1 Example 2 Example 3 Comparative example 2 Ganoderma lucidum fermented liquid 10 7 5 3 0 Dandelion Extract 0 3 5 7 10

Embodiment 4 and comparative example 3～4

[0076] Prepare the cosmetic water agents of Example 4 and Comparative Examples 3-4 according to the following table. Wherein, the cosmetic of Example 4 is composed of the antioxidant composition of Example 3, and the mass ratio of Ganoderma lucidum fermented liquid and Dandelion extract is 3:7.

[0077] Table 5. Recipe table

[0078]

[0079] Synthesize as follows:

[0080] (1) Weigh PEG / PPG-14 / 7 dimethyl ether, glycerol glucoside, betaine, add a part of deionized water and heat to about 50°C, stir and dissolve at 250-300r / min for 20min;

[0081] (2) Add phenoxyethanol and p-hydroxyacetophenone, keep the temperature at 50°C, stir and dissolve for 15 minutes;

[0082] (3) Add ganoderma lucidum extract and dandelion extract, lower the temperature to 35-45° C., stir to dissolve for 15 minutes, stir at 100 r / min for 15 minutes, and then cool to room temperature to prepare skin care products.

Embodiment 3

[0083] Test Example 3 Efficacy Evaluation

[0084] (1) Personnel recruitment: Human experiments were used to measure changes in skin hemoglobin, and 30 volunteers aged 18-30 who met the requirements were selected as test subjects. Recruitment criteria: the skin is fragile, prone to redness due to environmental influences such as temperature difference / season change, and the face has already been reddened before the test.

[0085] (2) Subject requirements:

[0086] (i) Informed consent has been signed, and all subjects who voluntarily participated in this test have received oral and paper informed consent in accordance with local regulations and procedures. Informed consent explains the nature, purpose and potential risks of participating in the research, and emphasizes the voluntariness of participating in the test, and subjects can withdraw from the research at any time for any reason. All subjects are allowed to ask questions about the study and are given sufficient time t...

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Abstract

The invention relates to the technical field of skin care products, in particular to an antioxidant composition as well as application and a product thereof. The antioxidant composition is composed of a ganoderma lucidum fermentation liquor and a dandelion extract. The ganoderma lucidum fermentation liquor and the dandelion extract are matched for use according to a certain proportion, the chain reaction in the oxidation process can be interrupted, the oxidation process is destroyed, meanwhile, generation of free radicals is inhibited, and a remarkable anti-oxidation effect is achieved. Experiments show that the anti-oxidation effect of the composition is obviously superior to that of independent ganoderma lucidum fermentation liquor or dandelion extract, and the dosage of active ingredients is obviously lower than that of independent ganoderma lucidum fermentation liquor or dandelion extract under the same DPPH free radical inhibition capacity, so that the ganoderma lucidum fermentation liquor and dandelion extract in the anti-oxidation composition have a synergistic effect in the anti-oxidation aspect; and the two are indispensable. In addition, the effects of the composition on the aspects of removing red skin and relieving skin are obviously better than the effect of using a single agent.

Description

technical field [0001] The invention relates to the technical field of skin care products, in particular to an antioxidant composition and its application and product. Background technique [0002] Solar radiation, environmental pollution, internal inflammation, etc. all generate reactive oxygen species and free radicals in the skin. This imbalance of redox state is the root cause of many pathological diseases, including skin aging damage, skin cancer, etc. Based on the redox imbalance, excessive free radicals continue to oxidize in the body in a chain reaction, causing cell damage. In addition, excessive free radicals will increase the activity of tyrosinase, speed up the process of pigment synthesis, and make it difficult for melanin granules to catabolize and gradually accumulate. Excess free radicals will also participate in the process of skin inflammation, participate in a series of signal transduction, and up-regulate the expression of inflammatory factors, thereby ...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/9728A61Q19/08A61Q19/00
CPCA61K8/9789A61K8/9728A61Q19/08A61Q19/00A61K2800/592A61K2800/85
Inventor 戴跃锋何广文颜少慰吕孙良
Owner HUNAN YUJIA COSMETICS MFG CO LTD
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