Sugar-coated tablet and preparation method thereof

Abstract

The invention relates to a sugar-coated tablet. The sugar-coated tablet comprises a tablet blank and a sugar coating wrapping the tablet blank. The tablet blank is obtained by carrying out shaping and tabletting operation on medicine granules, and the medicine granules are prepared from the following components in parts by weight: 30 to 40 parts of fructus xanthii, 10 to 15 parts of flos chrysanthemi indici, 20 to 22 parts of herba centipedae, 10 to 15 parts of seedless roxburgh rose, 10 to 15 parts of angelica keiskei, 20 to 22 parts of herba ecliptae, 10 to 15 parts of radix paeoniae alba, 6 to 8 parts of microcrystalline cellulose, 2 to 3 parts of magnesium stearate, 1 to 5 parts of sodium citrate and 0.05 to 0.1 part of chlortrimeton. The sugar coating is prepared from the following components in parts by weight: 5 to 10 parts of polyethylene glycol acrylate, 5 to 10 parts of triethylene glycol diacrylate, 5 to 15 parts of isomaltooligosacharide, 2 to 5 parts of lactose, 0.2 to 3 parts of stevioside, 0.5 to 1 part of erythritol, 0.5 to 1 part of mannitol and 5 to 10 parts of xylitol. The invention also relates to a preparation method of the sugar-coated tablet.

Description

technical field [0001] The invention relates to the field of rhinitis medicine, in particular to a sugar-coated tablet for treating chronic rhinitis and a preparation method thereof. Background technique [0002] Nasal Comfort Tablet has the functions of clearing heat, reducing inflammation and clearing orifices, and is used to treat sneezing, runny nose, nasal congestion, headache, allergic rhinitis and chronic sinusitis caused by chronic rhinitis. At present, the active ingredients in nasal comfort tablets can be mixed with conventional adjuvants and / or excipients to prepare various pharmaceutical dosage forms (such as capsules, tablets, granules, sugar-coated pills, solutions, etc.). Among them, commonly used excipients include: fillers and compatibilizers (such as starch, microcrystalline fibers, etc.), binders (such as carboxymethyl cellulose, polyvinylpyrrolidone, etc.), humectants (such as glycerol), disintegrating agents Agents (such as calcium carbonate, etc.), abs...

AI Technical Summary

Problems solved by technology

[0003] The applicant disclosed a nasal comfort tablet in the invention patent with the application number CN202010124485.0. The nasal comfort tablet includes the following traditional Chinese medicine components in parts by mass: 300-400 parts of cocklebur, 120-160 parts of wild chrysanthemum, goose 200-220 parts of non-grass, 100-120 parts of Angelica dahurica, 100-120 parts of Fangfeng, 200-220 parts of Eclipta, 130-160 parts of white peony, 60-80 parts of Dannanxing, 65-85 parts of licorice, 200 parts of Tribulus terrestris ~220 parts and 0.1~0.5 parts of chlorpheniramine. The nasal comfort t