32 results about "Erythrose" patented technology

The invention discloses a corynebacterium glutamicum engineering strain for biosynthesis of rare sugar, and a building method and application thereof, and discloses a corynebacterium glutamicum recombination strain SY10. An experiment proves that rare ketose and deoxidized ketose can be synthesized by adopting a plurality of hydroxyaldehydes and glucoses as substrates by the strain in a fermentation manner, for example, D-erythrulose can be synthesized by adopting formaldehyde and glucose as substrates, L-xylulose can be synthesized by adopting glycolaldehyde and glucose as substrates, D-sorbose and D-psicose can be synthesized by adopting D-glyceraldehyde and glucose as substrates, L-fructose can be synthesized by adopting L-glyceraldehyde and glucose as substrates, and 3R, 4S, 5R, 6R-heptose and 3R, 4R, 5R, 6R-heptose can be synthesized by adopting D-erythrose and glucose as substrates. Therefore, the corynebacterium glutamicum recombination strain SY10 disclosed by the invention can be applied to the field of production of the rare ketose and the deoxidized ketose by whole-cell fermentation; the produced rare ketose and deoxidized ketose have broad application prospects in the industries such as a food, a medicine and the like.

The invention provides a novel method for preparing high value-added chemicals by selectively photo-catalytically oxidizing glucose. The method is characterized in that glucose is directly converted into arabinose and erythrose by using rutile TiO2 loaded with a metallic promoter as a photocatalyst by a photo-catalytic dehydrogenating and oxidizing way under room temperature. The prepared arabinose and erythrose prepared by the method have the yields respectively reaching more than 45mol% and 26mol%; the reaction conditions are mild; no acid, alkali and organic solvents are added; and high-temperature and high-pressure conditions are not needed.

The invention discloses a fruity soda water with zero heat. The fruity soda water with zero heat mainly comprises, by weight, 0.01-1 part of stevioside, 0.1-10 parts of erythrose alcohol, 0.5-0.8 part of sodium bicarbonate, 0.0005-0.001 part of calcium chloride, 0.0005-0.001 part of magnesium sulfate, 0.0005-0.003 part of sodium sulfate, 0.5-0.8 part of natural perfume, 0.01202-0.166 part of vitamin ingredient and purified water dissolved with carbon dioxide. The fruity soda water with zero heat has simple and easily available raw materials, good mouthfeel and no heat, is suitable for diabetes patient, the obese and the group needing less energy intake, and has good health care function. Materials used in the invention contain no heat, provide a product with diversified taste and supplement everyday vitamin loss in human body; addition of erythritol benefits functions of metabolism and toxin expelling and satisfies diversified mouthfeel demand and pursuit of people for health.

The invention relates to the technical field of cosmetics, and discloses a multi-effect repair lyophilized film. The multi-effect repair lyophilized film comprises, by weight, 9-20 parts of trehalose,20-25 parts of hyaluronic acid, 10-15 parts of erythrose, 10-15 parts of pullulan, 15-20 parts of sclerotium gum, 5-15 parts of tetrahydromethylpyrimidine carboxylic acid, 5-10 parts of asiaticosideand 5-10 parts of oligopeptide. The multi-effect repair lyophilized film has the advantages that the trehalose, the hyaluronic acid, the tetrahydromethylpyrimidine carboxylic acid, the asiaticoside and the oligopeptide easily penetrate a deep layer of skin after compounding, so that the skin can quickly absorb nutrients to improve cell activity and moisturizing effect; the hyaluronic acid, the tetrahydromethylpyrimidine carboxylic acid and the asiaticoside can effectively reduce small wrinkles, and accordingly, the skin is firm and smooth.

The invention relates to a preparation method of 4-phosphoric acid erythrose, comprising the following steps: immobilizing heat-resistant transketolase at the temperature of 55-65 DEG C; and then taking 6-fructose phosphate and 3-glyceraldehyde phosphate as raw materials to prepare the 4-phosphoric acid erythrose by enzymatic reaction. In the preparation method, the heat-resistant and specifically transformed transketolase of the 4-phosphoric acid erythrose is prepared by adopting a molecular biology technology, and the 6-fructose phosphate and the 3-glyceraldehyde phosphate are taken as the raw materials to efficiently prepare the 4-phosphoric acid erythrose by adopting an immobilized enzyme technology. The preparation method is simple and practical.

The invention discloses mallotus oblongifolius buccal tablets and a preparation method of the mallotus oblongifolius buccal tablets. The mallotus oblongifolius buccal tablets comprise the following components in parts by weight: 32-40 parts of a mallotus oblongifolius extract, 10-15 parts of a licorice extract, 4-6 parts of honey, 7-10 parts of starch, 2-3 parts of erythrose and 3-5 parts of magnesium stearate. As containing the mallotus oblongifolius extract, the licorice extract, the honey, the starch, the erythrose and the magnesium stearate, the mallotus oblongifolius buccal tablets have the healthcare functions of diminishing inflammation, resisting bacteria, clearing heat, relieving summer heat, resisting fatigue, improving the capability of scavenging free radicals of organism and the like, and are suitable for different groups of people to eat. In preparation, the mallotus oblongifolius extract is taken as a main raw material and is matched with the licorice extract and other materials with components for clearing away heat and toxic materials to prepare the buccal tablets, and the buccal tablets attach importance to natural property and are free of pigments and flavoring agent, good in palatability, convenient to use, unique in taste and obvious in tea aroma. The preparation method is simple and the scale production is easy to implement.

There is provided the use as reducing agents of alpha-hydroxycarbonyl compounds capable of forming cyclic dimers. There is also provided corresponding methods of reducing reducible compounds, particularly reduction-activated prodrugs . Examples of the alpha-hydroxycarbonyl compounds used are dihydroxyacetone, glycolaldehyde , glyceraldehyde, erythrose, xylulose, erythrulose or 3-hydroxy-2-butanone.

The invention discloses a corynebacterium glutamicum engineering strain for biosynthesis of rare sugar, and a building method and application thereof, and discloses a corynebacterium glutamicum recombination strain SY10. An experiment proves that rare ketose and deoxidized ketose can be synthesized by adopting a plurality of hydroxyaldehydes and glucoses as substrates by the strain in a fermentation manner, for example, D-erythrulose can be synthesized by adopting formaldehyde and glucose as substrates, L-xylulose can be synthesized by adopting glycolaldehyde and glucose as substrates, D-sorbose and D-psicose can be synthesized by adopting D-glyceraldehyde and glucose as substrates, L-fructose can be synthesized by adopting L-glyceraldehyde and glucose as substrates, and 3R, 4S, 5R, 6R-heptose and 3R, 4R, 5R, 6R-heptose can be synthesized by adopting D-erythrose and glucose as substrates. Therefore, the corynebacterium glutamicum recombination strain SY10 disclosed by the invention can be applied to the field of production of the rare ketose and the deoxidized ketose by whole-cell fermentation; the produced rare ketose and deoxidized ketose have broad application prospects in the industries such as a food, a medicine and the like.

The invention discloses a low-calorie yogurt drink; every 100g low-calorie yogurt drink contains the components in the following weight: 10g to 80g of milk, 0.1g to 5g of stevia sugar, 3g to 10g of erythrose-alcohol, 0.1g to 1.0g of stabilizer, 0.2g to 0.7g of acidity regulator, 0.05g to 0.2g of natural spice, and pure water is added to 100g. Compared with the existing similar products, the low-calorie yogurt drink does not contain any calorie, sucrose is replaced by high-sweetness stevia sugar, the low-calorie yogurt drink is applicable to fat people and people who need to take less sugar, erythrose-alcohol is also added to facilitate the functions of metabolism and expulsion of toxin, simultaneously natural spice with various tastes is added, and the needs of people for health and the preference of the people for various taste are met.

The invention provides an organic water-soluble fertilizer containing humic acid and a preparation method thereof. The organic water-soluble fertilizer comprises the following raw materials in parts by weight, 14-18 parts of potassium fulvate, 10-30 parts of monoammonium phosphate, 10-30 parts of sodium selenite, 1-3 parts of erythritol, 2-4 parts of ethylenediamine tetraacetic acid disodium salt,0.3-2 parts of glycine betaine, 2.3-5 parts of borage seed oil, 1.2-3 parts of phytosphingosine and 0.3-0.9 part of secondary cracking yeast fermentation product lysate. According to the organic water-soluble fertilizer containing humic acid, the raw materials are scientifically proportioned and play a synergistic role, after crop surface spraying, plant nutrition can be provided, plant growth ispromoted, the fertilizer utilization rate is high, the fertilizer efficiency is good, the water-soluble effect is good, crop absorption can be facilitated, the yield is increased, and the heavy metalcontent of obtained crops is low.

The invention provides a multipurpose plant growth promoter. The multipurpose plant growth promoter is characterized by comprising the following components in parts by weight: 36-44 parts of purifiedwater; 4.5 to 5.5 parts of aspartic acid; 9 to 11 parts of threonine; 9 to 11 parts of glycine; 4.5 to 5.5 parts of arginine; 4.5 to 5.5 parts of boric acid; 4.5 to 5.5 parts of selenium; 1.8 to 2.2 parts of titanium citricate; 0.9 to 1.1 parts of ammonium molybdate; 13.5 to 16.5 parts of EDTA zinc; 2.7 to 3.3 parts of vitamin C; 4.5 to 5.5 parts of vitamin B12; 4.5 to 5.5 parts of polyglutamic acid; 4.5 to 5.5 parts of EDTA calcium; 1.8 to 2.2 parts of chitin; 2.7 to 3.3 parts of chitosan oligosaccharide; 2.7 to 3.3 parts of Tween 80 (auxiliary agent); 4.5 to 5.5 parts of EDTA iron; 1.8 to 2.2 parts of EDTA manganese and 9 to 11 parts of erythritol; the preparation method of the multipurpose plant growth promoter comprises the following steps: randomly putting 141 parts of the raw materials into a stirring reaction kettle according to the ratio, stirring for 20-30 minutes, and then filling and storing in vacuum. The multipurpose plant growth promoter provided by the invention has theadvantages of promoting fruit maturation, prolonging the fresh-keeping period and improving the yield and disease resistance of rice and wheat thereof.

The invention relates to a recombinant yeast, a construction method thereof and an application of the recombinant yeast in preparing tyrosol and derivatives. The recombinant yeast is obtained by introducing an exogenous fructose-6-phosphate phosphoketolase expression gene into a modified yeast cell, and the modified yeast cell is a yeast cell with a metabolic pathway of synthesizing tyrosol through 4-erythrose phosphate and phosphoenolpyruvic acid. The invention first discloses the fact that in a process of expressing fructose-6-phosphate phosphoketolase in yeast, fructose-6-phosphoric acid iscatalyzed into erythrose-4-phosphoric acid and acetyl phosphoric acid while 1,6-fructose diphosphate is synthesized, and xylulose-5-phosphoric acid is catalyzed into glyceraldehyde-3-phosphoric acidand acetyl phosphoric acid, so that distribution of the carbon metabolism flow in yeast is changed, synthesis of an important intermediate substance erythrose-4-phosphoric acid in tyrosol biosynthesisis enhanced, the metabolic pathway for synthesizing tyrosol is optimized, and the yield of tyrosol and derivatives such as hydroxytyrosol and the like is improved.

A recombinant yeast is constructed by introducing an expressed gene of exogenous Fructose-6-phosphate phosphoketolase into a modified yeast cell, and the modified yeast cell is a yeast cell with a metabolic pathway for synthesizing tyrosol via Erythrose-4-phosphate and phosphoenolpyruvate. The present invention discloses for the first time that in the process of expressing Fructose-6-phosphate phosphoketolase in a yeast, Fructose-6-phosphate is synthesized into beta-D-Fructose 1,6-bisphosphate and also catalyzed into Erythrose-4-phosphate and Acetyl-phosphate, and Xylulose-5-phosphate is catalyzed into Glyceraldehydes-3-phosphate and Acetyl-phosphate, which change the metabolic flux distribution of carbon in the yeast, enhance the synthesis of Erythrose-4-phosphate as an important intermediate for the biosynthesis of tyrosol, optimize the metabolic pathway for synthesizing tyrosol, and increase the yields of tyrosol and its derivatives such as hydroxytyrosol.

The invention belongs to the technical field of biomass conversion and chiral synthesis and particularly relates to a method for preparing D-erythrose from biomass saccharides. According to the invention, the biomass saccharides are adopted as the raw materials, and under the aqueous phase condition and the alkaline environment, the raw materials are catalyzed to obtain the D-erythrose. The method is has the following characteristics: the type of the biomass saccharides is more, the initial concentration range of the biomass saccharides is wide, the heating manner is flexible, the basicity range of a catalyst is wide, and the single chirality of the catalyst is realized; the operation is simple and convenient, equipment is simple, energy is saved, the aftertreatment is convenient, and both the percent conversion and the selectivity are high. As the D-erythrose is regarded as one of important platform chemical compounds at present, a series of products with wide application ranges can be obtained through chiral conversion and achiral conversion, can serve as midbodies of fine chemical engineering and pharmacy, and has huge economical value and broad application prospects. Therefore, through the method for efficiently preparing a great amount of D-erythrose from the biomass saccharides, large-scale industrialized production is expected to realize.

The invention relates to a chemical preparation method of erythritol. In the method, the erythritol is prepared by a chemical method, oxydol and a catalyst are used to carry out catalytic oxidation on gluconate to generate erythrose, and the erythrose is hydrogenated to be reduced into the erythritol, wherein the catalyst is cobalt chloride, and the gluconate is sodium gluconate. The chemical preparation method comprises the following steps: (1) preparing a sodium gluconate solution; (2) carrying out catalytic oxidation on the sodium gluconate; (3) carrying out primary refinement; (4) hydrogenating; (5) carrying out secondary refinement; (6) evaporating; (7) crystallizing; and (8) centrifuging: separating crystallized massecuite with a centrifuge, and drying to obtain the crystallized erythritol. The invention shortens the production period, is beneficial to improving the working efficiency, reduces the energy consumption and production cost, and solves the problems that fermentation conditions are difficult to control, microbiological contamination can be possibly caused, the fermentation period is long and the like. Besides, the invention avoids the waste of the liquid material, enhances the controllability, improves the efficiency and productive capacity, reduces the impurities in the liquid material, improves the crystal yield and product quality, and greatly lowers the production cost.

The invention discloses oral cavity disintegration tablets of anti lactose intolerance and lactase deficiency and a preparation method thereof. The formula of the invention comprises active component lactase, excipient diluent, sweet excipient, disintegrant, adhesive, wetting agent, glidants and lubricant. The diluent can use one or a plurality of mannitol, sorbitol, xylitol and erythrose; the sweet excipient can employ one or a plurality of fructoses, mannitol, xylitol, sucrose, aspartame and flavor; the disintegrant can adopt one or a plurality of sodium carboxymethyl starch, crosslinking carboxymethyl cellulose natrium, crosslinking povidone, low-substituted hydroxypropyl cellulose, microcrystalline cellulose and pre gelatinized starch; the adhesive can employ one from povidone, starch slurry and various cellulose types; the glidants can adopt micropowder silica gel or talcum powder; the lubricant can employ one from magnesium stearate, calcium stearate, stearic acid, hydrogenation vegetable oil and polyethylene glycol; the wetting agent can be selected one from ethanol, water and aqueous ethanol solution.

There is provided the use as reducing agents of alpha-hydroxycarbonyl compounds capable of forming cyclic dimers. There is also provided corresponding methods of reducing reducible compounds, particularly reduction-activated prodrugs. Examples of the alpha-hydroxycarbonyl compounds used are dihydroxyacetone, glycolaldehyde, glyceraldehyde, erythrose, xylulose, erythrulose or 3-hydroxy-2-butanone.

The invention discloses a ganoderma lucidum and propolis soft capsule. The preparation method comprises the following steps of completely dissolving propolis in heated olive oil, adding soyabean lecithin, uniformly mixing, adding a ganoderma lucidum extract, isomaltooligosacharide and part of maltodextrin powder, performing shearing and stirring, and emulsifying at low temperature to obtain ganoderma lucidum and propolis slurry contents; dissolving glycerin, part of erythritol and the rest maltodextrin powder in heated water, adding gelatin, performing stirring to dissolve completely, degassing in vacuum, adding the rest erythritol, and carrying out shearing and stirring to obtain a capsule shell glue solution; and then feeding the ganoderma lucidum and propolis slurry contents and the capsule shell glue solution into a pill pressing machine for pill pressing, shaping, drying, and performing softening to obtain the ganoderma lucidum and propolis soft capsule. The components of the softcapsule are easily absorbed by a human body, the immunocompetence of the human body is effectively enhanced, and meanwhile, the soft capsule is good in dispersion, fine and smooth in taste for oral administration and chewing, high in storage stability and free of the phenomena of coagulation, hardening, leakage, shrinking and the like.

The present invention relates to an ophthalmic solution comprising 0.00001 to 10.0 weight percent of a simple saccharide, at least 0.00001 weight percent of a preservative, and not more than about 0.2 percent by weight chloride. The simple saccharide is chosen from the group consisting of: inositol; mannitol; sorbitol; sucrose; dextrose; glycerin; propylene glycol; ribose; triose; tetrose; erythrose; threose; pentose; arabinose; ribulose; xylose; xylulose; lyxose; hexose; allose; altrose; fructose; galactose; glucose; gulose; idose; mannose; sorbose; talose; tagatose; adlose; ketose; heptose; sedoheptulose; monosaccharides; disaccharides; sugar alcohols; xylitol; and polyol.

The invention discloses an oxidation inhibitor, a carbon dioxide absorbent and a carbon dioxide absorption method thereof. The carbon dioxide absorbent includes a mixed aqueous solution of ethanolamine (MEA) and sulfolane (TMS) and an oxidation inhibitor, and the oxidation inhibitor is selected from glycerin, D-sorbitol, xylitol or erythritol. MEA and TMS are 25%-50% and 20%-50% respectively, and the oxidation inhibitor is greater than 0 and less than or equal to 10%. The carbon dioxide absorbent is added to the absorption tower to make it absorb and react with carbon dioxide gas to form a carbon dioxide absorbing liquid. The carbon dioxide absorbing liquid enters the phase separator and is allowed to stand for stratification to form a rich phase rich in carbon dioxide and an absorption phase poor in carbon dioxide. The enriched phase enters the desorption tower to desorb high-purity carbon dioxide, and the absorption phase returns to the absorption tower as a carbon dioxide absorbent to continue to participate in the absorption reaction. The invention has the advantages of good oxidation inhibition of the absorbent, high efficiency of carbon dioxide absorption and the like.

The invention relates to a preparation method of 4-phosphoric acid erythrose, comprising the following steps: immobilizing heat-resistant transketolase at the temperature of 55-65 DEG C; and then taking 6-fructose phosphate and 3-glyceraldehyde phosphate as raw materials to prepare the 4-phosphoric acid erythrose by enzymatic reaction. In the preparation method, the heat-resistant and specifically transformed transketolase of the 4-phosphoric acid erythrose is prepared by adopting a molecular biology technology, and the 6-fructose phosphate and the 3-glyceraldehyde phosphate are taken as the raw materials to efficiently prepare the 4-phosphoric acid erythrose by adopting an immobilized enzyme technology. The preparation method is simple and practical.

The invention discloses a method for further synthesizing acetyl coenzyme A by reacting glycolaldehyde with 4-erythrose phosphate under the catalysis of aldolase to generate 6-allose phosphate. The method disclosed by the invention is high in catalytic rate, the theoretical carbon yield of a reaction route is 100%, carbon loss is avoided, the 4-erythritol phosphate, the enzyme and the coenzyme can be recycled, and the reaction efficiency is relatively high. The method disclosed by the invention can play more obvious advantages in the production processes of in-vitro continuous multi-enzyme catalysis, fed-batch fermentation, continuous fermentation and the like capable of controlling the substrate level.

The invention belongs to the technical field of biomass conversion and chiral synthesis and particularly relates to a method for preparing D-erythrose from biomass saccharides. According to the invention, the biomass saccharides are adopted as the raw materials, and under the aqueous phase condition and the alkaline environment, the raw materials are catalyzed to obtain the D-erythrose. The method is has the following characteristics: the type of the biomass saccharides is more, the initial concentration range of the biomass saccharides is wide, the heating manner is flexible, the basicity range of a catalyst is wide, and the single chirality of the catalyst is realized; the operation is simple and convenient, equipment is simple, energy is saved, the aftertreatment is convenient, and both the percent conversion and the selectivity are high. As the D-erythrose is regarded as one of important platform chemical compounds at present, a series of products with wide application ranges can be obtained through chiral conversion and achiral conversion, can serve as midbodies of fine chemical engineering and pharmacy, and has huge economical value and broad application prospects. Therefore, through the method for efficiently preparing a great amount of D-erythrose from the biomass saccharides, large-scale industrialized production is expected to realize.

The invention provides a mud snail health beverage and a preparation method thereof. The raw material formula of the beverage is calculated by weight percentage: 5-15% of mud snail enzymatic hydrolysis solution, 3-10% of red nan fruit juice, and 0.2% of erythritol ~1.8%, 3~10% of Artemisia annua buds, 2~8% of Tudinggui, and the balance is drinking water; thereby, the present invention not only retains the original flavor of mud snails at full price and does not lose biologically active components, but also solves the problem of The problem of fishy smell of mud snails and restrictions on eating environment and eating methods, supplemented by red nan fruit juice, erythrose, artemisia buds, soil dinggui, etc. The physiologically active substances and nutritional and health ingredients are fully introduced into beverage products , produce synergistic effect and complement each other. Its color is light reddish, fragrant and mellow, delicious, and unique in flavor. It has better nutritional and health value and is easier for the human body to fully digest and absorb. Regular consumption can improve the body's immunity, prevent diseases, and strengthen the body. Effect.

The invention provides multi-flavor cola with zero heat, which overcomes the disadvantages of the conventional cola series beverages, does not contain any heat, has sweetness superior to that of the beverages in which sugar or other sweeting agents are added and is suitable for diabetics, obese patients and people needing to reduce energy intake to drink. The multi-flavor cola with zero heat comprises stevia sugar, erythrose, a natural perfume, a cola essence, an acidity acidifier and carbonated water serving as main raw materials, also comprises vitamin components and replenishes the vitamin of a human body lost every day. The beverage has the advantages of good mouthfeel, high safety, low production cost, convenience of carrying, high health value and the like.