Resin type matrix and its preparation method

Abstract

The invention discloses a resin type matrix and its preparation method wherein the resin type matrix comprises medical hot melt pressure-sensitive glue, rosin, zinc oxide, crystallite wax, ortho-phthalic acid dimethyl esters, and sorbic acid.

Description

Technical field [0001] The invention relates to a medicine matrix with a special physical form and a preparation method thereof, in particular to a resin matrix of an ointment patch and a preparation method thereof. Background technique [0002] There are mainly three types of existing ointment patch bases, namely black plaster, rubber gel and cataplasm base. The traditional black plaster of traditional Chinese medicine is made from traditional Chinese medicinal materials, sesame oil is extracted from medicinal oil at high temperature and lead Dan is boiled. Its disadvantage is that the process is complicated, the product quality is difficult to control, and the active ingredients of traditional Chinese medicine are easily destroyed during high temperature extraction. Due to the lead-containing products in the black plaster matrix, there is a risk of lead poisoning in patients using black plasters. In addition, the black plaster must be preheated t...

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Problems solved by technology

However, the main components used in the preparation of the drug plaster base are polymer compounds, especially polyvinyl chloride, which is toxic to the human body and should not be popularized.

Chinese invention patent application number 97107547.6, publication number 1201663, titled "a kind of medical plaster base", discloses a new type of plaster base (carrier), the base composition includes tung oil, linseed oil, sesame oil, castor oil, rosin, Edible gelatin, beeswax, glycerin, maltose, zinc oxide, powdery filler, the invention is dissolved in various traditional Chinese medicine extracts and then spread on the backing cloth to make the medical plaster base, the finished product does not contain Synthetic chemical raw materials such as polyvinyl chloride, most of the ingredients are natural oils, which are non-toxic to the human body and have good compatibility and release properties with Chinese medicinal extracts. However, due to the poor antioxidant properties of natural oils, they are prone to aging and failure Shortcomings such as fast, cause the medical plaster matrix described in this invention to be not resistant to storage, and the duration of drug effect is short

At the same time, the invention requires the raw materials to undergo polymerization reaction under certain temperature and pressure conditions to produce colloidal substances, but the polymerization reaction temperature is too high, the reaction is violent, and the active components in the traditional Chinese medicine are easily destroyed, resulting in the reduction of the curative effect of the medical plaster , the effect becomes worse

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