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Nuclear pore membrane composite medical dressing

A composite medical and nuclear pore membrane technology, used in medical science, bandages, absorbent pads, etc., can solve the problems of inducing infection, increasing the burden on medical staff, and absorbing saturation of wound exudate, achieving good mechanical strength and reducing patient pain. Painful, accelerated wound healing effect

Inactive Publication Date: 2006-05-24
长春吉原生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The above existing composite medical dressings used for the protection and treatment of burns, scalds, wounds and other wounds can basically meet the functions of isolating bacteria, absorbing exudate, ventilating, and providing a moist healing environment. , these medical dressings basically use an impermeable continuous gas-permeable membrane as the base material, because the water vapor transmission rate of this type of gas-permeable membrane is much lower than that of human skin, and the exudate of the wound site itself is relatively high. This can easily create fluid accumulation under the dressing and induce infection
In order to solve this problem, most of the existing medical dressings are compounded with an absorbent layer, but the absorbent layer also has the problem of saturated absorption of wound exudate.
Simultaneously, existing all kinds of dressings all can't accomplish the defect of directly administering medicine to the wound surface under special circumstances, therefore, when needing to change the dressing to the wound surface or when the dressing absorbs saturation, generally just need medical personnel to debride the wound and change the dressing in time, like this On the one hand, it increases the burden on medical staff, and at the same time, it brings unfavorable factors to patients' wound healing (such as increasing the chance of being infected, etc.)

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026]A polyurethane nuclear pore membrane with a thickness of 30 microns, a pore diameter of 5 microns and a permeability of 3% was selected, cut into 200 mm*150 mm in size, and sterilized by radiation after bagging. The attending doctor randomly selected 16 patients in Jishuitan Hospital. The total area of ​​burns was ≥10%-≤30%, and the third-degree area was ≥5%-≤10%. Using the same body control method, the nuclear pore membrane medical dressing was used to observe the treatment of II degree The clinical efficacy, safety and adverse reactions of burn wounds and surgical skin grafting areas, and compared with oil gauze. When using, first debride the wound with normal saline, and then choose a nuclear pore membrane medical dressing that is larger than the wound (there is no special regulation on the size of the nuclear pore membrane, generally about 2cm longer than the side of the wound) and directly cover it on the wound surface. The incision was secured with tape around it. ...

Embodiment 2

[0028] A PET nuclear pore membrane with a thickness of 25 microns, a pore diameter of 7 microns, and a permeability of 20% is used as the first layer of membrane, and a PET nuclear pore membrane with a thickness of 25 microns, a pore diameter of 10 microns, and a permeability of 30% is used as the second layer of membrane. It is cut into 100mm*100mm size, and then the two layers are bonded with pressure-sensitive adhesive. After compounding, the permeability is about 10%, the strength is improved, and other properties remain unchanged.

Embodiment 3

[0030] Choose a PET nuclear pore membrane with a thickness of 25 microns, a pore size of 7 microns, and a permeability of 20% as the base membrane, cut it into a size of 100mm*100mm, and then directly paste it with the transparent porous tape of 3M Company, and place it on the base membrane Coat pressure-sensitive adhesive around it, pack it into a bag, and sterilize it for preservation. After adopting this method, under the condition that other properties remain unchanged, the strength of the composite membrane is greatly improved compared with the single-layer membrane.

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PUM

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Abstract

The present invention relates to a nucleopore membrane composite type medical dressing. It includes basic membrane layer, said basic membrane layer is formed from single layer of nucleopore membrane or formed by superimposing several layers of nucleopore membranes, all the nucleopore membrane layers are successively up-down arranged according to the pore diameter from large to small, between membrane and membrane they are cohered together by means of pressure-sensitive adhesive, the pore diameter range of nucleopore membrane is 1-10 microns, its permeability range is 0.05%-50%, on one side of basic membrane layer directly-contacted with surface for wound a layer of skin friendly layer made up by selecting aquagel or silicon gel material is superimposed, on the side of basic membrane layer non-contacted with surface of wound a layer of reinforcing layer made up by using transparent porous semipermeable polymer material or non-woven fabric is superimposed.

Description

technical field [0001] The present invention relates to a composite medical dressing for protection and treatment of burns, scalds and traumatic wounds, in particular to a composite medical dressing whose base layer is a nuclear pore membrane with a micron-scale porous structure distributed on the surface . The invention also relates to the use of the nuclear pore membrane in the preparation of medical dressings. Background technique [0002] 1. Background technology of traditional medical dressings——Current status and shortcomings [0003] The composite medical dressings currently used for the protection and treatment of burns, scalds, and traumatic wounds mainly include the following types: [0004] (1) Coating medical pressure-sensitive adhesive on polyvinyl chloride, polyethylene, polypropylene, non-woven polyurethane and other backing materials, and directly pasting the prepared film on the wound surface as a medical dressing. [0005] (2) three-layer composite medic...

Claims

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Application Information

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IPC IPC(8): A61L15/26
Inventor 宋易阳孙永华周业平刘永辉罗志武甘云涛王真筠付绍海
Owner 长春吉原生物科技有限公司
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