Natural, chimeric and hybrid glycosaminoglycan polymers and methods of making and using same

a glycosaminoglycan and hybrid technology, applied in the field of polymer production methods, can solve the problems of difficult manipulation of membrane-bound synthase proteins, inability to achieve large-scale reaction reproducibility, and inability to control synthetic control and large-scale reactions. the effect of low to moderate repetitive yield
US20060188966A1Inactive Publication Date: 2006-08-24THE BOARD OF RGT UNIV OF OKLAHOMA
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
THE BOARD OF RGT UNIV OF OKLAHOMA
Publication Date
2006-08-24
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin / heparosan synthases from Pasteurella multocida, in order to create a variety of glycosaminoglycan oligosaccharides having a natural or chimeric or hybrid sugar structure.
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Description

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application claims benefit under 35 U.S.C. 119(e) of U.S. Provisional No. 60 / 305,263, filed Jul. 13, 2001, entitled “NANO HYALURONIC ACID AND METHODS OF MAKING AND USING SAME,” the contents of which is expressly incorporated herein in its entirety by reference.

[0002] This application is a continuation-in-part of copending U.S. Ser. No. 09 / 437,277, filed Nov. 11, 1999, entitled “POLYMER GRAFTING BY POLYSACCHARIDE SYNTHASES,” which claims benefit under 35 U.S.C. 119(e) of U.S. Provisional No. 60 / 107,929, filed Nov. 11, 1998, entitled “POLYMER GRAFTING BY POLYSACCHARIDE SYNTHASES,” the contents of both of which are expressly incorporated herein in their entirety by reference.

[0003] This application is also a continuation-in-part of copending U.S. Ser. No. 09 / 283,402, filed Apr. 1, 1999, entitled “DNA ENCODING HYALURONAN SYNTHASE FROM PASTEURELLA MULTOCIDA AND METHODS;” which claims benefit under 35 U.S.C. 119(e) of U.S. Provisional ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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