Uses of pulsatilla chinensis extract in preparing drug for treating viral and/or bacterial diseases

Abstract

Use of the compound Pulsatilla Saponin B4 represented by formula (I), or a pharmaceutically acceptable salt thereof in the preparation of a medicament for treating viral and / or bacterial diseases, and a medicament comprising the compound Pulsatilla Saponin B4 represented by formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient, wherein the disease is dairy cow mastitis.

Description

TECHNICAL FIELD[0001]The present invention relates to the use of Pulsatilla Chinensis extract in the preparation of a medicament for treating viral and / or bacterial diseases.BACKGROUND[0002]Pulsatilla Chinensis (Bge.) Regel is a Pulsatilla plant of Ranunculaceae family, and the main medicinal part thereof is its dry roots. The earliest record about Pulsatilla is “Shen Nong's Materia Medica”. It has a bitter taste, is cool-natured, and returns to the stomach, kidney, and large intestine meridians. The main functions of Pulsatilla are detumescence, cooling blood, stopping diarrhea, reducing internal heat, etc. Pulsatilla is traditionally used for the treatment of bacterial dysentery, and it also has good therapeutic effects on chill and fever symptoms, swelling and pain of eye. Pulsatilla has a variety of pharmacological activities, mainly to improve the body's ability to recognize and resist foreign body invasion, reduce the proliferation rate of tumor cells, reduce the number of pat...

AI Technical Summary

Benefits of technology

The patent text describes a natural active ingredient called Pulsatilla Saponin B4, which is a non-toxic and non-drug-resistant compound that has strong biological activity and is effective in treating dairy cow mastitis. Unlike traditional antibiotics, Pulsatilla Saponin B4 does not need to be discarded after treatment, reducing economic losses for farmers and reducing the risk of drug resistance. It also has excellent therapeutic effects on persistent and latent mastitis. In addition, Pulsatilla saponin injection is safe, efficient, and does not have any toxic or side effects.

Problems solved by technology

Other causes include improper milking operations, mechanical damage caused by trauma and damage caused by chemical reagents.

Dairy cow mastitis not only affects milk production and causes economic losses, but also affects the quality of milk and harms human health.

In addition, if this type of mastitis does not reach a certain proportion in the herd, it is generally not treated.

Because of its concealed incidence, the economic loss caused by latent mastitis to dairy cows is very serious.

However, long-term use of antibiotics is prone to drug resistance and affects the treatment effect; at the same time, when antibiotics are used for treatment, it is easy to cause antibiotic residues, pollute milk sources, and endanger human health.

It is worth noting that if mastitis is a Gram-negative bacterial infection, the use of lactam antibiotics will destroy the cell wall and release endotoxin, causing redness, swelling, heat, and pain in the entire udder area, which will aggravate the condition.

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