2 results about "Neurite growth" patented technology

The present invention addresses the problem of providing a novel technique for promoting neurite outgrowth activity. The present invention for solving the aforementioned e problem is a glial-cell-dependent neurite outgrowth promoter comprising an NF-κB decoy as an active ingredient, the glial-cell-dependent neurite outgrowth promoter being used in order to promote neurite outgrowth of nerve cells via glial cells.

The present application relates to the technical field of biological medicine, and particularly relates to a composition for protecting cochlear spiral ganglion neurons and application thereof. The composition comprises Panax notoginseng saponins (PNS) and Polygonatum sibiricum polysaccharide (PSP). Research shows that the composition can significantly improve the survival rate of neurons, promote neurite growth, reduce the level of reactive oxygen species, inhibit cell apoptosis, and promote autophagy by regulating the PI3K / AKT signaling pathway, thereby effectively resisting ototoxicity damage induced by aminoglycoside antibiotics. The present application further provides the use of the composition in the preparation of a drug for preventing or treating sensorineural hearing loss.