The invention discloses a pathological biopsy specimen bottle and belongs to the technical field of specimen storage. The specimen bottle is structured such that a center channel stretching upward isarranged on a fixed liquid storage device, a plurality of specimen bottle accommodating cavities are arranged in a specimen accommodating device, a fixed liquid injection pipe communicating to the center channel is arranged on the top of the center channel, the fixed liquid storage device communicates to the center channel through an infusion pump, and an electromagnet is arranged on the fixed liquid injection pipe; the specimen bottle comprises an outer bottle body and a liner, the liner is made from a soft material, filter screens are arranged at the bottom of the liner and around the liner,the fixed liquid injection pipe is arranged above the outer bottle body, a connecting end made from a hard material is arranged on the top of the liner, and the connecting end can be detachably connected to the outer bottle body. It is convenient to operate the liner of the specimen bottle, and addition and tissue separation of a fixed liquid are carried out simultaneously. Tissues attached to apuncture needle are separated by means of an impulse force of the fixed liquid, and the tissues are not destroyed and damaged. The pathological biopsy specimen bottle is convenient to operate and improves the detection accuracy.