50 results about "Pathology specimens" patented technology

The invention provides a pathological specimen auxiliary diagnosis system based on multi-thread control and task scheduling, and the system comprises a distributed lock management module which is used for employing a distributed lock to judge the operation state of a resource needed by a task based on a task initiation request, and distributing the lock and starting task execution when the needed resource is not locked; the timed task scheduling module is used for regularly scanning the task queue and distributing periodic tasks and delayed tasks in the task queue to a thread pool based on a scanning result; the multi-thread task execution module is used for performing multi-thread task scheduling and control on the periodic tasks and the delayed tasks according to a priority mechanism on the basis of the distribution result, and performing data processing on the periodic tasks and the delayed tasks on the basis of a multi-thread task scheduling and control result; and the loop operation management module is used for releasing the lock after the execution is finished, and notifying the idle thread to continuously process the to-be-processed task in the task queue based on a release result. And the efficiency and the effect of auxiliary diagnosis of the pathological specimen are ensured.

Systems and methods are disclosed for identifying a diagnostic feature of a digitized pathology image, including receiving one or more digitized images of a pathology specimen, and medical metadata comprising at least one of image metadata, specimen metadata, clinical information, and / or patient information, applying a machine learning model to predict a plurality of relevant diagnostic features based on medical metadata, the machine learning model having been developed using an archive of processed images and prospective patient data, and determining at least one relevant diagnostic feature of the relevant diagnostic features for output to a display.

The invention provides an examination system suitable for pathology teaching, which is based on a pathology database, combines with examination key points, automatically generates examination papers, answers and submits the examination papers based on identity information of users, and combines with a multimedia technology and a remote teaching means based on the pathology database. Pathology simulation practice operation is designed for online practice of a user, and a practice operation result is obtained; based on the test paper result and the practical operation result, performing pathological knowledge mastering evaluation on the user to obtain a user evaluation result; the problem that a traditional examination form is difficult to comprehensively evaluate learning results of students is solved, the examination system suitable for pathology teaching can provide diversified evaluation means, learning conditions of the students can be more comprehensively understood by comprehensively evaluating knowledge mastering degrees of the students, and meanwhile, by means of a multimedia technology and a remote teaching means, the learning results of the students can be comprehensively evaluated. More practical opportunities are provided for students, observation and analysis experience of the students on pathological specimens is increased, and practical operation ability is improved.

Systems and methods for processing tissue samples are provided. Tissue samples are obtained and disposed into individual compartments of a cassette with an embedded barcode identifier, which is scanned to generate a display screen of digital images and a reference table. Cassettes with tissue samples are stored and shipped in one formalin filled jar to a pathology facility, where the cassettes are removed and wiped of formalin. Digital images of lidless cassettes are generated and measured by a pathology information system. The ends of each tissue sample are color coded and the tissue samples dehydrated. The tissue samples and an orientation dot are embedded in a paraffin block, which is trimmed and mounted to a slide. Digital images of the tissue samples on the slide are generated and stored by the pathology information system. The digital images may be analyzed by a doctor and / or artificial intelligence programs for abnormal pathology.

The utility model relates to the field of medical instruments, in particular to a pathological specimen bag which comprises a specimen bag body, a sealing strip is installed at the top end of the specimen bag body, a pathological specimen storage inner cavity is installed on the inner side of the specimen bag body, a connecting block is installed at the bottom end of the specimen bag body, and four connecting clamping grooves are installed at the bottom end of the connecting block. Dismounting buttons are mounted on the surfaces of the connecting blocks, and connecting rods are mounted on the inner sides of the dismounting buttons. According to the pathological specimen bag, the hard plastic bottom supporting and fixing base can be inserted into the connecting block connected to the bottom of the specimen bag body through the connecting buckle block, so that the bottom of the pathological specimen bag can be fixedly and vertically placed, pathological specimens can be observed and operated more conveniently, and the fixity of the device is greatly improved; the transparent plastic ruler on the surface of the pathological specimen bag can slide horizontally, so that parameters of an internal solution or a pathological specimen can be observed conveniently, and the practicability of the device is greatly improved.

A computer-implemented method for processing digital pathology images, the method including receiving a plurality of digital pathology images of at least one pathology specimen, the pathology specimen being associated with a patient. The method may further include determining receiving metadata corresponding to the plurality of digital pathology images, the metadata comprising data regarding previous medical treatment of the patient. Next, the method may include providing the medical images and metadata as input to a machine learning system, the machine learning system having been trained by receiving as input historical treatment information and digital images labeled with a predicted treatment regimen. Lastly, the method may include outputting, by the machine learning system, a treatment effectiveness assessment.

This utility model discloses a testing device for pathological specimens, relating to the technical field of pathological specimen testing equipment. It includes a placement box, a testing mechanism, and a movable seat. The placement box has a hinged door on its front. The testing mechanism is mounted on the top of the placement box and is connected to it. Two first sliding grooves are formed on the bottom surface of the placement box. The bottom of the movable seat is slidably connected to the two first sliding grooves via a sliding connector. Two second sliding grooves are formed laterally on the top of the movable seat. An adjustable clamping and fixing mechanism is included, comprising a limiting frame, a bearing seat, a double-ended lead screw, a brake motor, and a clamping base. The limiting frame is fixed to the top of the movable seat by multiple support legs, and a through-hole limiting groove is formed inside the limiting frame. This utility model can be applied to the limiting and fixing of test tubes of various sizes, greatly improving the applicability and practicality of the device.

The utility model provides a bone tumor pathological specimen slice preservation device which comprises a preservation box and a placing structure, the placing structure comprises a driving box and two containing boxes, the driving box is vertically and fixedly connected to the bottom of the inner wall of the preservation box, and the two containing boxes are vertically and fixedly connected to the bottom of the inner wall of the preservation box. The two containing boxes are fixedly connected to one side and the other side of the bottom of the inner wall of the storage box correspondingly, a threaded rod is rotatably and vertically arranged in an inner cavity of the driving box, and a plurality of first threaded sleeves are connected to the surface of the threaded rod in a threaded mode. According to the bone tumor pathological specimen section preservation device, a threaded rod reversely rotates to drive a plurality of preservation boxes and a movable rod to descend, after a sponge cushion makes contact with the surface of a tumor pathological specimen section, a spring contracts to generate elastic force, the elastic force reacts on the tumor pathological specimen section, and then the tumor pathological specimen section can be clamped and fixed; and the tumor pathological specimen slice is more stable in the use process.

Disclosed herein are embodiments of compositions, methods and kits that describe ancillary reagent constructs for simultaneous immunological and morphological investigation of pathology specimens. The kits include reagents, possibly organized in panels, which give the pathologist additional confidence in making a diagnosis based on the morphology of a cell. Reagents can be used or selected to identify specific antigens or a class of antigens. The reagents further comprise detection agents, which are visible under standard microscopy in the presence of standard stains. The reagents, used on their own or as part of a kit, make possible immunological analysis simultaneously with pathology performed in the presence of standard stains.

The present invention discloses a method for processing pathological specimens. The method includes: fixedly arranging an image acquisition camera above the specimen placement table, and when a specimen to be processed is placed on the specimen placement table, acquiring a first image of the specimen to be processed captured by the image acquisition camera. Then, based on the morphology of the specimen to be processed in the first image, determining the long axis and short axis of the specimen to be processed, and controlling a spray gun to spray pigments of different colors through the specimen placement table onto both sides of the long axis. Determining a plurality of equally spaced cutting lines according to the short axis, and controlling a cutting knife to cut along each cutting line to obtain a plurality of cut specimens. Finally, numbering all the cut specimens along the direction of the long axis according to the cutting lines. It can be seen that the present invention can realize the standardized processing of pathological specimens, greatly reduce the subjective error rate of pathological specimen processing, and reduce the working difficulty of manual pathological sampling. In addition, a pathological specimen processing device, equipment, and storage medium are also proposed.

The utility model discloses a pathological specimen bag with a specimen size measuring function, which comprises a pathological bag body, the pathological bag body consists of an upper bag body, a lower bag body and a turnover bag body, an information note is arranged on the front side of the lower bag body, and grid measuring lines are arranged on the back side, the bottom and two sides of the lower bag body. Through cooperative use of the pathological bag body, the information note, the grid measuring lines, the pressing sealing strip and other structures, a pathological specimen can be sealed after being put into the pathological bag body, and meanwhile, the overturning bag body is overturned, so that the hands of medical personnel are prevented from being polluted by an internal channel of the pathological bag body, and the medical personnel is prevented from being damaged by the internal channel of the pathological bag body. Then the length, the width and the height of the pathological specimen are measured through the grid measuring lines and the graduated scale in different directions, so that subsequent medical staff can accurately add reagents, and the problems that the reagents are wasted or expected effects of the reagents cannot be achieved due to the fact that the reagents are added too much or too little are solved; and the accuracy of subsequent examination of the pathological sample is improved.

1. The name of this design product: Pathological specimen storage box. 2. Purpose of this design product: used for storing pathological specimens. 3. The design key point of this appearance design product lies in the shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The utility model belongs to the technical field of specimen boxes, and particularly relates to a pathological specimen classification box which comprises a pathological specimen box body, the pathological specimen box body is composed of a main box body and a plurality of auxiliary box bodies, box covers and grooves are arranged on the main box body and the auxiliary box bodies, and the main box body and the auxiliary box bodies are connected with the main box body and the auxiliary box bodies. A label box is further arranged on the main box body, a clamping base B is further arranged on the auxiliary box body, a clamping base A is arranged in the groove, a clamping groove is formed in the clamping base A, a clamping hole is formed in the clamping base A, the clamping hole is communicated with the clamping groove, and the clamping base A is connected with the clamping base B in a clamped mode. According to the pathological specimen box, the pathological specimen box body is composed of the main box body and the auxiliary box bodies, and after the box bodies with the corresponding number are combined and connected, pathological specimens at different positions can be classified and stored, so that checking and finding are facilitated, and the risks of cross contamination and leakage of the specimens are prevented.

The utility model relates to a medical instrument, in particular to a pathological specimen transfer box which comprises a box body, a retention clamp and a fixing device. Sliding holes are formed in the side walls of the opposite sides of the box body respectively. The retention clamp comprises a pair of clamping pieces used for clamping the specimen bag; the two ends of the retention clamp are movably arranged in the opposite sliding holes respectively, and at least one end of the retention clamp is provided with a tightening piece used for limiting movement of the retention clamp in the sliding holes. The fixing device is a blade type adjusting seat with a center opening and is used for limiting the specimen bottle; the fixing device is arranged at the inner bottom of the box body. Compared with the prior art, the utility model solves the defects that the specimen bag is easy to leak and cannot be suitable for specimen bottles with multiple specifications in the transfer process in the prior art, and realizes the effects that the specimen bag can be well fixed, and the specimen bottles with different sizes can be fixed to prevent the specimen bottles from toppling over in the transfer process; and different types of specimens can be orderly conveyed to a pathology department in the transfer box.

A computer-implemented method for processing digital pathology images, the method including receiving a plurality of digital pathology images of at least one pathology specimen, the pathology specimen being associated with a patient. The method may further include determining, using a machine learning system, whether artifacts or objects of interest are present on the digital pathology images. Once the machine learning system has determined that an artifact or object of interest is present, the system may determine one or more regions on the digital pathology images that contain artifacts or objects of interest. Once the system determines the regions on the digital pathology images that contain artifacts or objects of interest, the system may use a machine learning system to inpaint or suppress the region and output the digital pathology images with the artifacts or objects of interest inpainted or suppressed.

The pathological specimen collecting box comprises a box body and a cover, the upper end face of the box body is provided with a storage bin which is concave inwards, an installation block is arranged in the storage bin, the upper end face of the installation block is provided with an installation shaft, the outer wall of the installation block is provided with an isolation block, and the isolation block is provided with a clamping groove. The cover is rotationally connected to the outer wall of the mounting shaft, a plurality of sets of mounting plates are arranged in the storage bin, a plurality of containing plates are mounted on the front end faces of the mounting plates, fixing assemblies are arranged on the upper end faces of the containing plates, and an opening is formed in the upper end face of the cover. According to the design, by arranging the multiple sets of mounting plates, the containing plates and the fixing assemblies, pathological specimens collected by the same patient can be stored on one set of mounting plates, and the same pathological specimens of different patients can also be stored, so that the corresponding pathological specimens can be found more clearly and visually when the pathological specimens are stored or taken out, and the classified storage effect and flexibility are improved; the use feeling is improved.

Methods for processing tissue samples are provided. Tissue samples are obtained and disposed into individual compartments of a cassette with an embedded barcode identifier, which is scanned to generate a display screen of digital images and a reference table. Cassettes with tissue samples are stored and shipped in one formalin filled jar to a pathology facility, where the cassettes are removed and wiped of formalin. Digital images of lidless cassettes are generated and measured by a pathology information system. The ends of each tissue sample are color coded and the tissue samples dehydrated. The tissue samples and an orientation dot are embedded in a paraffin block, which is trimmed and mounted to a slide. Digital images of the tissue samples on the slide are generated and stored by the pathology information system. The digital images may be analyzed by a doctor and / or artificial intelligence programs for abnormal pathology.

The utility model relates to the technical field of clinical pathological diagnosis, in particular to a pathological specimen cutting knife for clinical pathological diagnosis, which comprises a knife body arranged in a cutting groove on a cutting box, a baffle plate and two push plates, the knife body comprises a knife back and a knife edge, the baffle plate is fixed on one side of the knife back, and the two push plates are respectively fixed on two sides of the bottom of the knife back. Two positioning blocks are fixed at one end in the cutting groove, and residues after specimen cutting are prevented from falling into the cutting groove through a baffle; the pushing device is located on one side of the cutting groove, and the pushing device abuts against the knife back; after a specimen is cut by the blade, specimen residues slide to the outer side of the cutting groove through the baffle, and when the cutter body is replaced through the pushing device, the push plate at the bottom of the cutter back pushes out the residues in the cutting groove, so that the situation that insertion of subsequent bodies is affected due to the fact that the specimen residues of the cutter fall into the cutting groove is prevented.

Systems and methods are described herein for processing electronic medical images to predict a biomarker's presence, including receiving one or more digital medical images, the one or more digital medical images being of at least one pathology specimen associated with a patient. A machine learning system may determine a biomarker expression level prediction for the one or more digital medical images. The biomarker expression level prediction may be based on a determined transcriptomic score and protein expression score for the one or more digital medical images. A slide overlay indicating a region of tissue on the one or more digital medical images that is most likely to contribute to the slide level biomarker expression prediction may be generated.

The invention relates to the related technical field of clinical pathology department equipment, in particular to a pathological specimen fixing and transferring device which comprises a bottom plate, a lifting mechanism is arranged on the upper surface of the bottom plate, and a sealing and fixing mechanism is arranged on the lower surface of the lifting mechanism. According to the pathological specimen fixing and transferring device, through the arrangement of the lifting mechanism and the sealing and fixing mechanism, when the pathological specimen fixing and transferring device is used, a control motor can conveniently put a specimen into a fixing tank or take the specimen out of the fixing tank filled with fixing liquid, a sealing ring is clamped into a sealing groove of a sealing block to form tight sealing connection, and the sealing environment in the fixing tank is guaranteed; by means of cooperative work of the lifting mechanism and the sealing and fixing mechanism, a user can conveniently place a specimen into the stationary liquid and take the specimen out of the stationary liquid without making direct contact with the stationary liquid, the whole specimen fixing and transferring process is smoother and more convenient, and working efficiency and safety are improved.

The utility model discloses a medical filterable small pathological tissue specimen bag, including specimen bag body and the top sealing press -fitting strip of setting in the inside of specimen bag body top end opening, the bottom sealing press -fitting strip of specimen bag body bottom end opening inside is provided with, the top sealing press -fitting strip and bottom sealing press -fitting strip and specimen bag body inner wall between close adhesion, and top sealing press -fitting strip and bottom sealing press -fitting strip and specimen bag body junction still adopt the encryption processing of sealing glue, the inside of specimen bag body is provided with filter screen, the filter screen is plastic dense mesh, the medical filterable small pathological tissue specimen bag of this new type is applicable to the collection pathological specimen when transurethral resection of prostate plasma cutting, laser enucleation, cystectomy, reduces the tissue collection time, reduces the pathological tissue loss risk, improves pathological tissue quality, increases the operation efficiency, solves the problem of time -consuming and labor -intensive when specimen collection, smaller tissue loss.

This product is a digital pathology device for capturing pathological specimens (glass slides) as digital images (virtual slides) for management, analysis, etc. The images shown in the "front view," "plan view," and "enlarged view of the display section" display various information related to the status of the cassettes (glass slides) placed on the slide carousel, and are also used for operations to enable the digital pathology device to perform its functions.

The invention relates to the technical field of medical instruments, and discloses a pathological specimen standardized fixing and transporting integrated device which comprises a specimen transparent bag, and a control assembly is installed on the outer surface of the specimen transparent bag; the transparent specimen bag comprises a front side bag fixedly installed in the transparent specimen bag, and the surface of the front side bag is fixedly connected with a rear side bag. According to the standardized fixing and transporting integrated device for the pathological specimen, through the arrangement of the specimen transparent bag and the control assembly, when the standardized fixing and transporting integrated device is used, the pathological specimen is placed in the specimen transparent bag, the bag opening is closed, and at the moment, the microswitch triggers the timer to start timing; a group of fixed display time is recorded when the metal detection lines on the two sides in the transparent specimen bag detect liquid signals, when the specimen in-vitro time needs to be checked, only the display result on the flexible display screen needs to be observed, and meanwhile the flexible display screen can display the number of times of opening the transparent specimen bag.

The utility model discloses a respiratory pathology specimen storage box, including a heat preservation tube and a box cover, wherein the box cover is composed of an assembly ring that can be threadedly connected to the heat preservation tube, and a rotating cover that is rotatably installed on the upper end of the assembly ring, the upper surface of the rotating cover is provided with a specimen taking structure, and the interior of the heat preservation tube is provided with a refrigeration structure and a specimen preservation structure. The respiratory pathology specimen storage box, by providing a refrigeration structure, a specimen taking structure and a specimen preservation structure, compared with the prior art, the device can refrigerate the pathology specimen by using the cold air emitted by the ice bag, without the need for the refrigerator and the fan in the prior art to refrigerate, thereby reducing the production cost of the device, and at the same time, the rotatable rotating cover can be used to rotate the operation window to the top of the pathology specimen that needs to be taken out, so that the pathology specimen can be taken out by using the operation window, without opening the entire box cover, thereby avoiding a large amount of cold air loss in the storage cavity.

The utility model relates to the technical field of medical instruments, and discloses a pathological specimen collecting container convenient for sampling, which comprises a shell, the inner wall of the shell is fixedly connected with a connecting ring, the outer part of the connecting ring is in threaded connection with a top cover, the interiors of the left side and the right side of the top cover are respectively provided with a sliding chute, the interiors of the sliding chutes are in sliding connection with sliding blocks, and the sliding blocks are in threaded connection with the connecting ring. A first spring is fixedly connected to the right side of the sliding block, a connecting plate is fixedly connected to the top of the sliding block, a connecting block is fixedly connected to the bottom of the sliding block, a connecting plate is fixedly connected to the bottom of the connecting block, and a connecting block is fixedly connected to the bottom of the connecting plate. According to the specimen taking and placing device, operation is easy and convenient, the second connecting ring can be easily limited and relieved by the connecting block by moving the connecting plate inwards or outwards, specimens can be placed and taken out, the specimen taking and placing process is simplified, the operation difficulty is reduced, and the working efficiency is improved.

The utility model provides a manual negative-pressure specimen suction collector, which belongs to the technical field of medical instruments and comprises a shell, a first suction tube, a second suction tube and a second suction tube. The rotating disc is located in the shell, a first penetrating part and a second penetrating part are arranged on the rotating disc, and through rotation of the rotating disc, the first penetrating part and the second penetrating part alternately correspond to the positions of the drainage channel and the first notch; one end of the handle is located outside the shell, and the other end of the handle extends into the shell, is rotationally connected with the shell and is provided with a first transmission part; the rotating piece is located in the shell, one end of the rotating piece is connected with the turntable, and the other end is provided with a second transmission part matched with the first transmission part; and the filter screen disc is detachably mounted in the second penetrating part. According to the pathological specimen collector, pathological specimens can be conveniently collected, and the collected pathological specimens can be taken down from the collector in time and properly stored, so that the problem of confusion generated when a plurality of pathological specimens are synchronously collected is avoided, and the reliability of pathological specimen collection is improved.

Systems and methods are disclosed for analyzing an image of a slide corresponding to a specimen, the method including receiving at least one digitized image of a pathology specimen; determining, using the digitized image at an artificial intelligence (Al) system, at least one salient feature, the at least one salient comprising a biomarker, cancer, cancer grade, parasite, toxicity, inflammation, and / or cancer sub-type; determining, at the Al system, a salient region overlay for the digitized image, wherein the Al system indicates a value for each pixel; and suppressing, based on the value for each pixel, one or more non-salient regions of the digitized image.

Systems and methods are disclosed for analyzing an image of a slide corresponding to a specimen, the method including receiving at least one digitized image of a pathology specimen; determining, using the digitized image at an artificial intelligence (AI) system, at least one salient feature, the at least one salient comprising a biomarker, cancer, cancer grade, parasite, toxicity, inflammation, and / or cancer sub-type; determining, at the AI system, a salient region overlay for the digitized image, wherein the AI system indicates a value for each pixel; and suppressing, based on the value for each pixel, one or more non-salient regions of the digitized image.

Methods for processing tissue samples are provided. Tissue samples are obtained and disposed into individual compartments of a cassette with an embedded barcode identifier, which is scanned to generate a display screen of digital images and a reference table. Cassettes with tissue samples are stored and shipped in one formalin filled jar to a pathology facility, where the cassettes are removed and wiped of formalin. Digital images of lidless cassettes are generated and measured by a pathology information system. The ends of each tissue sample are color coded and the tissue samples dehydrated. The tissue samples and an orientation dot are embedded in a paraffin block, which is trimmed and mounted to a slide. Digital images of the tissue samples on the slide are generated and stored by the pathology information system. The digital images may be analyzed by a doctor and / or artificial intelligence programs for abnormal pathology.

The utility model is suitable for the technical field of pathological specimen sampling devices, and provides a tissue pathological specimen sampling device which comprises a base, the servo motor is fixed at the central position of the outer wall of one side of the base through a bolt; the ball screw is fixed at the output end of the servo motor; the inclined table is fixed on a nut seat on the ball screw through a screw; the blade clamping seat is welded on the outer side wall of the inclined table; the fixed plate is fixed at the position, close to one side of the inclined table, of the top of the base through a bolt; the sliding seat slides on the outer side wall of the fixed plate; the handle is screwed on the outer side wall of the sliding seat through a thread; through rotation of the pathology limiting cover in the vertical direction and rotation of the pathology limiting cover in the horizontal direction, the slicing position and the slicing angle of the tissue pathology specimen can be adjusted, so that the relative position of the blade and the pathology tissue is adjusted, and slicing sampling of the pathology tissue in different directions is facilitated; uniformity and flatness of the section of the tissue slice are guaranteed in a repeated lifting slicing mode.