Preparation of nano-coating micropore surface implant having regeneration activity and antibacterial property

A nano-coating and antibacterial technology, which is applied in the field of preparation of nano-bionic coating microporous surface artificial implant medical materials, can solve the problem of affecting the stability and life of the coating, osteolysis and joint porosis, and prone to phase change Brittle cracks and other problems, to achieve the effect of easy control of microstructure and coating thickness, strong wear resistance, and stable surface biological activity
CN101862269AInactive Publication Date: 2010-10-20杭州伟智生物医药科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
杭州伟智生物医药科技有限公司
Publication Date
2010-10-20
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to the preparation of a nano-coating micropore surface implant having a regeneration activity and an antibacterial property. The preparation is characterized in that the implant is a dental implant taking pure titanium or titanium alloy as a matrix and an artificial joint medicinal hard tissue implant material; and the surface of a matrix material is subjected to micro-roughness treatment, improved biomimetic liquid treatment and nano silver grain coating technology treatment to form a nano biomimetic coating structure having the regeneration activity and the antibacterial property, wherein the nano silver grain is a metallic silver elementary substance which is attached to the surface of the implant and has the antibacterial property and a tissue repairing function, and has the grain diameter of 6 to 50nm; and a nano coating crystal grain formed on the surface of the implant through treatment and induction is a bone-like hydroxyapatite material rich in calcium and phosphor. The micro-nano biomimetic coating implant has a bone-promoting regeneration activity and a high affinity; compared with an un-coating material, the coating implant is improved in the bonding force with bones by several times so as to effectively avoid the phenomena of loosening and shedding and to be a novel medicinal implant material having both the antibacterial property and the regeneration activity.
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Description

Technical field

[0001] The invention relates to a technology for preparing medical materials for artificial implants (such as dental implants and artificial bone and joint implants) with nano bionic coating microporous surface with regenerative biological activity and antibacterial properties. Background technique

[0002] Biomedical Materials and Biomedical Instruments are a type of high-tech new materials developed in the past 20 years. They are used to replace or repair human tissues and organs and enhance their physiological functions. Artificial materials and biological equipment, as well as biomedical materials and products have been commonly used in health, treatment and prevention fields.

[0003] For a long time, various implants made of metals (such as cobalt, stainless steel, pure titanium, etc.), ceramics or polymers have been used clinically to replace materials. However, these materials are bioactive, biocompatibility, and biological guidance. It has its own shortcom...

Claims

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