Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Application of candida tropicalis to preparation of xylitol and application of high-purity xylitol product to pharmacy and health care

A technology of Candida tropicalis and xylitol, which is applied in the biological field and can solve problems such as high cost and cumbersome process

Active Publication Date: 2013-05-01
唐传生物科技(厦门)有限公司
View PDF10 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0039] The purpose of the present invention is to solve the problems of cumbersome process and high cost in the existing hemicellulose hydrolysis physical chemical detoxification process

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of candida tropicalis to preparation of xylitol and application of high-purity xylitol product to pharmacy and health care
  • Application of candida tropicalis to preparation of xylitol and application of high-purity xylitol product to pharmacy and health care
  • Application of candida tropicalis to preparation of xylitol and application of high-purity xylitol product to pharmacy and health care

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0145] operation 1

[0146] Weigh 3 kg of bagasse that has been washed and re-dried, add H2SO4 solution (2.5%, w / w) at a solid-to-liquid ratio (w / v) of 1:7, hydrolyze at 120 ° C for 2 h, collect the filtrate by centrifugation, wash the filter residue once, and combine The filtrate was adjusted to pH 3 with solid calcium carbonate, and the precipitate was removed by suction filtration to obtain bagasse hemicellulose hydrolyzate. The reducing sugar content of the hydrolyzate is 3%, and xylose monosaccharide accounts for more than 80% of the total sugar.

[0147] operation 2

[0148] Take 2 kg of crushed dry corncobs, add 2% (w / w) H at a solid-to-liquid ratio of 1:7 2 SO 4 The solution was hydrolyzed at 120°C for 2 hours, the liquid part was collected, neutralized with calcium carbonate to a pH value of 3, and the precipitate was removed by suction filtration to obtain a dilute acid hydrolyzate of corncob hemicellulose. The total sugar content of the hydrolyzate is 5%, wherei...

Embodiment 2

[0170] Specific steps 1

[0171] 40kg corn husks, add 160L of water, boil. Filter off the liquid part, wash the residue once with water, add 80 L of 2% (w / w) sulfuric acid solution to the dried residue, and hydrolyze in a hydrolysis reactor at 125°C for 2 hours. Remove the residue by filtration, adjust the filtrate to pH 3 with calcium carbonate, remove the precipitate by filtration, add 1 kg of activated carbon to the filtrate, remove the activated carbon after adsorption treatment for 30 minutes, and then pass through the cation and anion exchange chromatography columns in turn to obtain a colorless and transparent syrup , and concentrated to the required concentration under reduced pressure. The content ratio of glucose, xylose and arabinose in this syrup is approximately 1:2:1.

[0172] Specific steps 2

[0173] Add 280L of 2.4% (w / w) sulfuric acid solution to 40Kg of dried bagasse, and hydrolyze at 125°C for 2 hours. The remaining subsequent processing steps are the s...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to application of candida tropicalis, a microbial fermentation and separation method for preparing xylitol by using the candida tropicalis, and application of a high-purity xylitol product prepared by using the method to pharmacy and health care. The xylitol has high output quality and high yield, and the product can be used as a sweetener, a nutritional supplement and an auxiliary treatment agent for diabetes patients. Moreover, the xylitol product can serve as a medicinal intermediate for preparing health-care toothpaste, health-care chewing gum, health-care sweet foodor sweet beverage and the like.

Description

technical field [0001] The invention belongs to the field of biotechnology, and relates to the use of Candida tropicalis to prepare xylitol and the pharmaceutical and health care uses of high-purity xylitol products. Background technique [0002] Hemicellulose is a polysaccharide other than cellulose in the plant cell wall. The content varies with different plants, accounting for 20-35% of the weight of the plant. It is the most abundant polysaccharide on the earth except cellulose. [0003] Cellulose is a homogeneous polysaccharide composed entirely of glucose units, while hemicellulose is mainly composed of xylose with β-(1-4) glycosidic bonds to form the main chain, and arabinose, mannose and galactose form branches. Non-uniform glycans with a chain structure. The xylan backbone of hemicellulose generally contains 50-150 xylose units, has no crystalline structure, and is bound to the surface of cellulose microfibrils. [0004] Hemicellulose is much easier to hydrolyze t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C12P19/02A61K31/7004A61P3/10A61P1/02A61P3/04A23L1/29C12R1/74A23L33/00
Inventor 张厚瑞覃香香蔡爱华周玉恒陈海珊
Owner 唐传生物科技(厦门)有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com