Freeze-dried powder preparation for curing bovine mastitis

Abstract

The invention belongs to the technical field of medicine, in particular relating to a freeze-dried powder preparation for curing bovine mastitis. The preparation disclosed in the invention comprises the following components by weigh percent: 0.04-1.5wt% of lysostaphin, 10-72.5wt% of lysozyme, 10-40wt% of retardant, 5-20% of monopotassium phosphate and 10-35% of disodium hydrogen phosphate. When the preparation is poured into the bovine breast, the lysostaphin and lysozyme can maintain favorable stability and sterilization vigor in milk, and flocculent precipitates generated by polymerization of lysostaphin or lysozyme with casein never appear in milk.

Description

technical field

[0001] The invention relates to a pharmaceutical preparation, in particular to a freeze-dried powder preparation for treating cow mastitis. Background technique

[0002] Dairy cow mastitis is a common, complex disease that causes the most serious economic losses in the dairy industry. At home and abroad, large doses of antibiotics are often used to treat dairy cow mammary gland infection. Although antibiotics have certain curative effects, most of the above-mentioned pathogenic bacteria have produced drug-resistant strains, so the curative effect is not obvious. On the contrary, it causes antibiotic residues in the milk, and the consequences of mixing the milk produced by these cows into the edible milk are serious. Both the Food and Agriculture Organization of the United Nations and the World Health Organization recommend that the milk expressed within at least 3 days after the withdrawal of antibiotic treatment from cows should not be directly used as raw ...

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