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Medical high-sensitivity micro needle array electrode

A microneedle array, high-sensitivity technology, used in applications, medical science, other medical devices, etc., can solve problems such as poor signal and low sensitivity, and achieve the effect of solving low sensitivity and improving input and acquisition.

Inactive Publication Date: 2012-10-31
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Using microneedles as a transdermal method solves the problem of high impedance of the skin, effectively improves the input and collection of bioelectrical signals, solves the disadvantages of low sensitivity and poor signal of conventional electrode products in practical applications, and improves detection, monitoring, Effects of Imaging and Therapy

Method used

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  • Medical high-sensitivity micro needle array electrode
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  • Medical high-sensitivity micro needle array electrode

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1 Construction of Highly Sensitive Microneedle Array Electrodes for Left and Right EEG

[0031] The whole microneedle array electrode is constructed using the left and right style, such as figure 1 and 2 shown. First, metal microneedles were selected as the materials of the three microneedles 101, 103 and 105, and a layer of dodecyl mercaptan 102 was modified by gas phase self-assembly, and a small amount of sodium dodecyl was doped at the same time. These alkyl groups play a role in improving the biocompatibility of the surface of the microneedle, while improving the electrical conductivity of the surface and reducing the resistance of the film. In order to facilitate the access of external instruments, a layer of gold film was sputtered on the backside of the three microneedle materials to reduce the ohmic contact resistance and improve the signal sensitivity of external instruments. The polymer material 109 of polydimethylsiloxane is used for bonding to fo...

Embodiment 2

[0032] Example 2 Construction of Highly Sensitive Microneedle Array Electrodes for Up-and-Down EEG

[0033] The whole microneedle array electrode is constructed using the up-and-down formula, such as image 3 and 4 shown. In Example 1, after sputtering a layer of gold film, the microneedle electrode parts 101, 103 and 105 are arranged smoothly up and down. After a certain force is applied, the microneedles will pierce the supporting structure to form three kinds of microneedles A complex of interlaced electrode structures. In order to prevent short circuit during the piercing process, it can be immersed in an insulating polymer solution such as polyethylene before piercing. Polyethylene plays both an insulating and a lubricating role. After grouping, if there is polyethylene residue on the tip of the microneedle electrode, it can be removed by immersing the tip of the microneedle in acetone. In this way, the construction of the relevant electrode system is completed. In t...

Embodiment 3

[0034] Example 3 Construction of Highly Sensitive Microneedle Array Electrodes for Layered ECG

[0035] The overall microneedle array electrode structure is constructed layer by layer, such as Figure 5 and 6 As shown, a metal microneedle 201 is selected, and a thin layer of polylactic acid 202 is modified by liquid phase assembly, in which ammonium lactate is doped to improve electrical conductivity and play a role in biocompatibility and electrical conductivity. The whole system is then immersed in Toulon's reagent to form a conductive silver coating 206, which part serves as part of the external wiring of the reference electrode. Then a part of the microneedle is submerged in a polymethyl methacrylate (PMMA) solution to modify a PMMA insulating layer 203 , and the part not coated with PMMA forms the reference electrode part of the electrode system. Repeat the above operation steps to construct the part of the signal electrode and the stimulation electrode to form a whole ...

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Abstract

The invention relates to a medical high-sensitivity micro needle array electrode which is an electrode product integrating an electrode and a micro needle. The micro needle penetrates into skin to reduce the skin resistance and realizes the dry acquisition or the input of stimulating signals or matters. The medical high-sensitivity micro needle array electrode has the characteristics of high efficiency, zero pains and the like. Through the medical high-sensitivity micro needle array electrode, the acquisition quality and the acquisition speed of the signals can be improved, the signal to noise ratio can be improved, and the sensitivity of the signal can also be improved by utilizing additional drugs and supporting matters to be favorable for improving the relevant process treatment effect and accelerating the disease curing time. The product can be subjected to body index long-time monitoring and detection through program design and set according to the practical demands of the patient and other relevant crowds and can also be treated according to the stimulation of the signals acquired and inputted at intervals as required. The medical high-sensitivity micro needle array electrode can be used for phototherapy, electrotherapy, acupuncture and moxibustion, ultrasonic wave and other treatment fields. The high-sensitivity micro needle array electrode is described in structural design and implemented key technology and has a wide application prospect.

Description

Technical field: [0001] This patent relates to the field of medical equipment and medicine, specifically to the field of high-sensitivity, low-noise medical electrodes and electrode sheets. technical background [0002] Through the contact coupling with the living body, the sensitive element that can effectively derive the potential and biological current in the living body is called a detecting electrode (Detecting electrode). Specifically, it can be divided into: production of physiotherapy self-adhesive electrodes, physiotherapy electrode sheets, non-woven electrode sheets, viscose electrode sheets, ear clip electrode wires, medical wires, electrode wires, therapeutic instrument wires, medium and low frequency therapeutic apparatus output wires, massage Electrodes, etc., can generally be summarized as medical electrodes. [0003] In today's era of extensive development and improvement of medical equipment, medical electrodes provide doctors and patients with material and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00A61B5/00A61N1/36
Inventor 张晓安杨秉杰吴宝山
Owner JILIN UNIV
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