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Silver ion sterilizing dispersible tablet as well as preparation process and application thereof in removal of residual bacteria on fruits and vegetables

A preparation process and technology of silver ions, applied in the fields of application, botany equipment and methods, chemicals for biological control, etc., can solve the problems of the biological cycle of aquatic organisms, increased toxicity and side effects, and poor bactericidal effect, etc., to achieve Excellent bactericidal effect, no toxic side effects, and the effect of solving human health hazards

Inactive Publication Date: 2013-05-15
兰州北陆生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In daily life, it is difficult to match the concentration of such a solution, and its adhesion and foaming are stronger, which increases the toxic and side effects on the human body
In the production of pesticides, a large number of surfactants are used to make the bacteria remaining in fruits and vegetables generally resistant to pesticides. Washing fruits and vegetables with detergents containing surfactants often has poor sterilization effects
In addition, the extensive use of detergents containing surfactants will have a long-term impact on the biological cycle of aquatic organisms

Method used

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  • Silver ion sterilizing dispersible tablet as well as preparation process and application thereof in removal of residual bacteria on fruits and vegetables
  • Silver ion sterilizing dispersible tablet as well as preparation process and application thereof in removal of residual bacteria on fruits and vegetables
  • Silver ion sterilizing dispersible tablet as well as preparation process and application thereof in removal of residual bacteria on fruits and vegetables

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0128] A silver ion bactericidal dispersible tablet for killing bacteria on the surface of fruits and vegetables, its formula is:

[0129]Main ingredients: 5.0g nano-silver particles, 14.0g γ-aminobutyric acid, 10.0g inositol hexaphosphate, 15.0g glutathione;

[0130] Filler: mannitol 44.5g, microcrystalline cellulose 5.0g;

[0131] Binder: Hydroxypropyl cellulose 3.0g

[0132] Disintegrant: 6.0g cross-linked polyvinylpyrrolidone, 5.0g L-HPC;

[0133] Glidant: Micro silica gel 1.5g;

[0134] Lubricant: sodium stearyl fumarate 1.0g;

[0135] The total weight is 110 grams, and a total of 1000 pieces are made.

[0136] Its preparation process adopts the direct compression method, as follows:

[0137] Step 1: Take nano-silver particles, γ-aminobutyric acid, inositol hexaphosphate, and glutathione raw material particles, weigh them, and mix them evenly for later use;

[0138] Step 2: Mix mannitol, microcrystalline cellulose, micropowder silica gel, cross-linked polyvinylpyrro...

Embodiment 2

[0141] A silver ion bactericidal dispersible tablet for killing bacteria on the surface of fruits and vegetables, its formula is:

[0142] Main ingredients: 5.0g of nano-silver particles, 5.0g of complex silver ions, 12.0g of γ-aminobutyric acid, 10.0g of inositol hexaphosphate, and 8.0g of glutathione;

[0143] Filler: dextrin 13.0g, sorbitol 3.5g;

[0144] Binder: pregelatinized starch 2.0g, polyethylene glycol 1.0g

[0145] Disintegrant: sodium hydroxymethyl starch 34.0g, croscarmellose sodium 10.0g;

[0146] Glidant: talcum powder 1.0g;

[0147] Lubricant: glyceryl monostearate 5.5g;

[0148] The total weight is 110 grams, and a total of 1000 pieces are made.

[0149] Its preparation process adopts the direct compression method, as follows:

[0150] Step 1: Take nano-silver particles, complex silver ions, γ-aminobutyric acid, inositol hexaphosphate, and glutathione raw material particles, weigh them, and mix them evenly for later use;

[0151] Step 2: Mix dextrin, so...

Embodiment 3

[0154] A silver ion bactericidal dispersible tablet for killing bacteria on the surface of fruits and vegetables, its formula is:

[0155] Main ingredients: complexed silver ion 5.0g, γ-aminobutyric acid 15.0g, inositol hexaphosphate 15.0g, glutathione 9.0g;

[0156] Binder: polyvinylpyrrolidone 1.0g;

[0157] Effervescent agent: citric acid 20.5g, sodium bicarbonate 13.0g;

[0158] Filler: mannitol 13.0g, starch 5.5g;

[0159] Disintegrant: 4.5g cross-linked polyvinylpyrrolidone, 6.5g sodium hydroxymethyl starch;

[0160] Glidant: Micropowder silica gel 1.0g;

[0161] Lubricant: sodium stearyl fumarate 1.0g;

[0162] Total weight 110g, made into 1000 pieces

[0163] Its preparation process adopts effervescent agent method, specifically as follows:

[0164] Step 1: Take the main ingredients and mix them with citric acid, crush them, granulate them with polyvinylpyrrolidone, pass through a 26-mesh sieve, and set aside:

[0165] Step 2: Take sodium bicarbonate and pulveri...

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Abstract

The invention discloses a silver ion sterilizing dispersible tablet which comprises the following components by weight percent: 10-40% of main materials, 0.5-5% of bonding agent, 15-45% of filling agent, 10-40% of disintegrating agent, 0-35% of effervescing agent, 0.1-3% of flow aid and 0.5-5% of lubricating agent, wherein the main materials comprise one or combination of two of nanometer silver particles and complex silver ions, as well as gamma-aminobutyric acid, inositol hexaphosphate and glutathione. The silver ion sterilizing dispersible tablet enters into a single-cell bacterial body by utilizing the silver ions to interfere metabolism of the single-cell bacterial body and damage protein capsid and DNA (deoxyribonucleic acid) molecules of the single-cell bacterial body so as to kill the single-cell bacterial body. When the bacterial body is inactivated, the silver ions drift away for re-sterilizing, so that the anti-bacterial effect is lasting. Meanwhile, the sterilizing effect of the silver ions is not influenced by drug resistance, so that the killing effect of pathogenic bacteria with drug resistance is good and new drug resistance is not produced at the same time due to mechanism of action.

Description

technical field [0001] The invention relates to a bactericide for cleaning fruit and vegetable bacteria, in particular to a silver ion bactericidal tablet. Background technique [0002] Existing fruit and vegetable cleaning agents are mainly detergents containing surfactants. Surfactants are mainly used to clean hard surface objects, such as "porcelain plates, porcelain bowls, etc." Surfactants have strong adsorption and foaming properties. Use detergents containing surfactant ingredients to clean fruits and vegetables. Surfactants will penetrate into the pulp of fruits and vegetables. When heated above 70 degrees Celsius, it will produce toxic side effects. Use will accumulate in the human body. The surfactant achieves the bactericidal effect by destroying the outer membrane of the organism at a concentration of 10%-20%. In daily life, it is more difficult to match the concentration of such a solution, and its adhesion and foaming properties are stronger, which increases...

Claims

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Application Information

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IPC IPC(8): A01N25/34A01N59/16A01N55/02A01P1/00
Inventor 阎昭良
Owner 兰州北陆生物科技有限公司
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