Ultrathin-wall microtubule production device and production method thereof

Abstract

The invention discloses an ultrathin-wall microtubule production device and a production method thereof. The ultrathin-wall microtubule production device comprises a nitrogen gas cylinder, a pressure reducing valve, a PU (poly urethane) tube, a caliber conversion device, a thick-wall microtubule, a left microtubule gripper, a right microtubule gripper, another caliber conversion device, a high-precision barometer, a back pressure valve, a long-stroke and high-precision micro displacement platform, a hydrogen-oxygen producing machine, a gas dryer, a gas flow controller, a flame gun, a flame-gun clamping device and a short-stroke and high-precision micro displacement platform. The production method includes that nitrogen with precisely-controlled barometric pressure enters an inner cavity of the microtubule, from the caliber conversion device, to apply outward pressure upon a tubule wall of the microtubule; oxyhydrogen with precisely-controlled flow rate forms oxyhydrogen flame, at a position of a nozzle of the flame gun, to evenly heat the thick-wall microtubule; the microtubule grippers with precisely-controlled speed and distance evenly stretch the microtubule to obtain the ultrathin-wall microtubule finally. The ultrathin-wall microtubule produced by the method is smooth in the tubule wall, a resonant cavity is constructed to ensure a good field evanescent function and a high Q value, and the time for producing one ultrathin-wall microtubule is less than 30 minutes.

Description

Technical field [0001] The invention relates to a biosensor of photobiology and chemical sensing technology, in particular to an ultrathin-walled microtube manufacturing device and a manufacturing method with a photomicrofluidic sensing resonant cavity. Background technique [0002] The label-free biosensor based on micro-resonance optical technology is directly used to measure molecular interactions, which can realize real-time observation of biomolecular interactions. Because there is no need for the analyte to be tested to have special properties such as fluorescence, characteristic absorption or scattering bands, the range of measurement objects is greatly expanded, and toxins, proteins, DNA, and even the entire cell behavior can be detected, which is useful for medical diagnosis, drug development, food monitoring, and environment Monitoring and other fields provide powerful analysis tools. [0003] The optical micro resonant cavity uses total reflection to completely confine ...

AI Technical Summary

Problems solved by technology

[0007] The first method is to melt and stretch first, and then corrode the inner wall. Although the required ultra-thin-walled quartz microtube resonator can be obtained, the tube wall is rough due to post-corrosion treatment of the microtube.

The Q value of the WGM sensing ultra-thin-walled quartz microtube resonator decreases, thereby affecting the sensitivity of the biodetector; at the same time, due to the limitation of the corrosion rate, the time to manufacture the WGM sensing ultra-thin-walled quartz microtube resonator is generally within 5 more than an hour

The second nanoscroll method, although it has the potential for large-scale integration, also cannot guarantee a sufficiently high Q value due to the corrosion of the surface.

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