Traditional Chinese medicine injection for treating severe acute pancreatitis and preparation method

A technology for acute pancreatitis and injection, which is applied in the field of traditional Chinese medicine injection and preparation for the treatment of severe acute pancreatitis, which can solve the problems of severe infection, high mortality, and many complications, reduce pathological and physiological damage, and inhibit inflammation Responses, effects, effects

Inactive Publication Date: 2014-01-22
孙立新
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently, the cure rate for patients with mild acute pancreatitis is relatively high, but for severe acute pancreatitis, due to its acute onset, severe condition, many complications, and extremely high mortality, most patients die of multiple organ failure and severe infection. How to improve the severity of acute pancreatitis? The cure rate and mortality reduction of acute pancreatitis has always been a hot spot and difficulty in clinical research

Method used

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  • Traditional Chinese medicine injection for treating severe acute pancreatitis and preparation method
  • Traditional Chinese medicine injection for treating severe acute pancreatitis and preparation method
  • Traditional Chinese medicine injection for treating severe acute pancreatitis and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] The raw material composition and the weight of Chinese medicine injection active ingredient of the present invention are:

[0053]

[0054] The preparation method of Chinese medicine injection of the present invention comprises the following processing steps:

[0055] (1) Take Huhuanglian, hawthorn and lotus root, wash them, squeeze the juice, and get the juice for later use;

[0056] (2) Take sargassum, linseed and scutellaria baicalensis to remove impurities, wash them, dry them, put them in a mortar, grind them into powder, pass them into 200 mesh fine powder, and set aside;

[0057] (3) Take Corydalis and Desmodium, add 5 times the amount of 80% ethanol solution to reflux for extraction for 2 hours, filter, and obtain the filtrate for later use;

[0058] (4) Take Magnolia officinalis, Corydalis, Gardenia, Citrus aurantium and Danshen to remove impurities, wash them, dry them in the sun, put them in a container, add 8-12 times the amount of distilled water, soak ...

Embodiment 2

[0064] The raw material composition and the weight of Chinese medicine injection active ingredient of the present invention are:

[0065]

[0066] The process steps of the preparation method of Chinese medicine injection in this embodiment are the same as those in Embodiment 1.

Embodiment 3

[0068] The raw material composition and the weight of Chinese medicine injection active ingredient of the present invention are:

[0069]

[0070] The process steps of the preparation method of Chinese medicine injection in this embodiment are the same as those in Embodiment 1.

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Abstract

The invention relates to a traditional Chinese medicine injection for treating severe acute pancreatitis and a preparation method. The effective ingredients of the traditional Chinese medicine injection are prepared from raw materials: rhizoma picrorhizae, glabrous sarcandra herb, haws, corydalis tuber, linseed, scutellaria baicalensis, mangnolia officinalis, radix bupleuri, corydalis bungeana, cape jasmine, desmodium, lotus rhizome, rheum officinale, immature bitter orange, salvia miltiorrhiza and mirabilite. The compatibility of the raw materials is good. The traditional Chinese medicine injection accords with traditional Chinese medicine and modern pharmacological research theories, and prepared by utilization of modern and advanced pharmaceutical technologies. The traditional Chinese medicine injection has functions of clearing heat, detoxifying, activating blood and dissolving stasis, can alleviate autodigestion of pancreatic tissues to inhibit inflammatory response through inhibition of pancreatic secretion functions, promotes pancreas microcirculation and intestine peristalsis, has functions of protecting intestinal tract barriers, prevents translocation of intestinal flora, can decrease pathological and physical damage caused by severe acute pancreatitis obviously, and has important effects on preventing and treating intestinal bacterial translocation and enterogenic infection. The traditional Chinese medicine injection has remarkable effects and low cost, is safe, has no poisonous or side effects, and is worth of popularization and application widely.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine injection for treating severe acute pancreatitis and a preparation method thereof. Background technique [0002] Acute pancreatitis is a common disease in gastroenterology. Acute pancreatitis is an inflammatory reaction in which pancreatic tissue is digested, edema, hemorrhage, or even necrosis after activation of pancreatic enzymes due to various causes. [0003] The main symptoms of acute pancreatitis are abdominal pain, nausea, vomiting, and fever, while hemorrhagic and necrotic pancreatitis may cause shock, high fever, jaundice, abdominal distension, intestinal paralysis, peritoneal irritation, and subcutaneous congestion. Clinically, it is characterized by acute epigastric pain, nausea, vomiting, fever, and increased blood trypsin. Lesions vary in severity. Pancreatic edema is the main symptom in mild cases, which is more common in ...

Claims

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Application Information

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IPC IPC(8): A61K36/80A61K9/08A61P1/18A61K33/04
Inventor 孙立新纪晓李勇卢纪杰
Owner 孙立新
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