Organic polyurethane foam dressing and preparation method thereof

A polyurethane foam and organic technology, applied in medical science, bandages, absorbent pads, etc., can solve the problems of inability to achieve long-term antibacterial, wound dressing adhesion, and high cost of antibacterial agents, so as to achieve less adhesion to the wound, reduce exudation, and operate convenient effect

Active Publication Date: 2014-12-24
HENAN HUIBO MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional wound dressings (such as gauze and cotton) have many disadvantages: they are easy to breed bacteria, and the wound exudate easily forms scabs with dry dermal tissue, which hinders epithelialization; at the same time, the wound is easy to adhere to the dressing, causing pain when the dressing is removed , causing secondary trauma
Although the antibacterial flexible polyurethane foam has an antibacterial effect, it cannot achieve long-term antibacterial inhibition, and the cost of antibacterial agents is high and the dosage is large.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The organic polyurethane foam dressing of the present invention is made of the following raw materials in proportion by weight: 20 parts of common polyether polyols, 20 parts of styrene-type grafted polyether polyols, 15 parts of ethylenediamine, 2 parts of pentane, 1 part of polymethylsiloxane-polyether copolymer, 1 part of ferrocene, 0.1 part of polyhexamethylene guanidine salt, 20 parts of hexamethylene diisocyanate, 1 part of pure water.

[0026] The method for preparing above-mentioned organic polyurethane foam dressing can be carried out in the following steps:

[0027] ① Weigh the common polyether polyol, styrene-type grafted polyether polyol, ethylenediamine, pentane, polymethylsiloxane-polyether copolymer, ferrocene, poly Hexamethylene guanidine salt and pure water were stirred at room temperature and 4000r / min for 50s to form a mixed solution;

[0028] ② Weigh the hexamethylene diisocyanate in the above weight ratio and add it to the mixed solution prepared i...

Embodiment 2

[0032] The organic polyurethane foam dressing of the present invention is made of the following raw materials in proportion by weight: 10 parts of ordinary polyether polyol, 40 parts of acrylonitrile-type grafted polyether polyol, 17 parts of ethylenediamine, and 3 parts of methylene chloride , 2.5 parts of low molecular weight alkoxy dimethylpolysiloxane, 2.5 parts of stannous 2-ethylhexanoate, 0.4 parts of triclosan, 50 parts of 4,4'-diphenylmethane diisocyanate, 2 parts of pure water .

[0033]The method for preparing above-mentioned organic polyurethane foam dressing can be carried out in the following steps:

[0034] ①Weigh the common polyether polyol, acrylonitrile type grafted polyether polyol, ethylenediamine, methylene chloride, low molecular weight alkoxy dimethyl polysiloxane, 2-ethyl polysiloxane and Stannous hexanoate, triclosan and pure water were stirred at room temperature for 55 seconds under the condition of 4000r / min to prepare a mixed solution;

[0035] ②...

Embodiment 3

[0039] The organic polyurethane foam dressing of the present invention is made of the following raw materials in proportion by weight: 7.5 parts of ordinary polyether polyol, 52.5 parts of acrylonitrile-type grafted polyether polyol, 20 parts of ethylenediamine, trichlorofluoromethane 4 parts, 5 parts of low molecular weight high alkyl modified dimethylpolysiloxane, 5 parts of triethylenediamine, 0.8 part of chlorhexidine gluconate, 100 parts of toluene diisocyanate, 2 parts of pure water.

[0040] The method for preparing above-mentioned organic polyurethane foam dressing can be carried out in the following steps:

[0041] ①Weigh the common polyether polyol, acrylonitrile-type grafted polyether polyol, ethylenediamine, trichlorofluoromethane, low molecular weight high alkyl modified dimethyl polysiloxane respectively , triethylenediamine, chlorhexidine gluconate and pure water, at room temperature, stirred for 60s under the condition of 4000r / min to make a mixed solution;

...

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PUM

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Abstract

The invention provides an organic polyurethane foam dressing and a preparation method thereof. An antibacterial component is added into a polyurethane foam synthesis formula to prepare polyurethane foam with an antibacterial function; the obtained polyurethane foam is subjected to low-temperature plasma surface modification treatment; a plasma membrane layer is added on the surface of the antibacterial polyurethane foam material to form a speed limiting barrier. The polyurethane foam dressing prepared by the preparation method disclosed by the invention is high in compliance to a wound and is soft and comfortable; the preparation technology is simple, is convenient to operate and good in treatment effect, has the characteristic of long-time bacteriostat and is suitable for industrial production.

Description

technical field [0001] The invention belongs to the technical field of polyurethane foam dressings, and in particular relates to an organic polyurethane foam dressing and a preparation method thereof. Background technique [0002] Skin damage caused by trauma, burns, and skin ulcers will cause a series of problems in the body, such as bacterial infection, increased metabolism, excessive loss of water and protein, endocrine and immune system dysfunction, etc., which may be life-threatening in severe cases. Therefore, after skin injury, it is usually necessary to use a skin substitute medical dressing to protect the wound, prevent wound infection and severe dehydration, provide a moist environment conducive to wound healing, and promote wound healing. During the wound healing process, the use of medical dressings can form a physical barrier to prevent dust, bacteria, etc. from entering the wound, facilitate wound care, and promote wound healing. [0003] In recent decades, wi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/34A61L15/48A61L15/46
Inventor 朱天钢刘尧李延浩周新钦
Owner HENAN HUIBO MEDICAL CO LTD
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