Biological lysozyme compound preparation and preparation method thereof

A technology of biological lysozyme and compound preparation, which is applied in the field of antibacterial and bactericidal preparations, can solve the problems of narrow scope of application, and achieve the effect of accelerating tissue repair, definite curative effect, and no drug resistance and drug resistance

Inactive Publication Date: 2015-07-29
JIANGSU XUE BAO DAILY CHEM CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this reagent is mainly aimed at oral lesions, and its scope of application is narrow.

Method used

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  • Biological lysozyme compound preparation and preparation method thereof
  • Biological lysozyme compound preparation and preparation method thereof
  • Biological lysozyme compound preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A biological lysozyme compound preparation, its components include: sorbitol 6 (wt)%, hydrated silica 20 (wt)%, aluminum hydroxide 12 (wt)%, glycerin 18 (wt)%, lauroyl sarcosine Sodium 2 (wt)%, food flavor 1.3 (wt)%, cellulose gum 0.8 (wt)%, carrageenan 0.4 (wt)%, hydroxyethyl cellulose 0.3 (wt)%, sodium phytate 0.6 (wt) %, sodium saccharin 0.3(wt)%, strontium chloride 0.3(wt)%, trisodium phosphate 0.3(wt)%, lysozyme 0.1(wt)%, amino acid 0.3(wt)%, proteolytic enzyme 2ppm, lysozyme Coccus enzyme 30ppm, peroxidase 3ppm, borneol 0.1(wt)%, borax 0.15(wt)%, cinnabar 0.08(wt)%, xuanming powder 0.12(wt)%, allantoin 0.4(wt)%, the balance for pure water.

[0016] The preparation method of the above-mentioned lysozyme is as follows: put corn flour, protein powder, beef jelly, and amino acids into a fermenter, add water to dissolve, sterilize, and cool; then inoculate and cultivate, culture conditions: temperature 37 ° C, stirring speed 600 rpm, tank pressure 0.03 MPa, pH change...

Embodiment 2

[0019] A biological lysozyme compound preparation, its components include: sorbitol 10 (wt) %, hydrated silica 18 (wt) %, aluminum hydroxide 20 (wt) %, glycerin 10 (wt) %, lauroyl sarcosine Sodium 3 (wt)%, food flavor 1 (wt)%, cellulose gum 1.2 (wt)%, carrageenan 0.6 (wt)%, hydroxyethyl cellulose 0.5 (wt)%, sodium phytate 1.2 (wt) %, sodium saccharin 0.15(wt)%, strontium chloride 0.5(wt)%, trisodium phosphate 0.2(wt)%, lysozyme 0.2(wt)%, amino acid 0.5(wt)%, proteolytic enzyme 4ppm, lysozyme Coccal enzyme 60ppm, peroxidase 5ppm, borneol 0.15(wt)%, borax 0.1(wt)%, cinnabar 0.1(wt)%, xuanming powder 0.15(wt)%, allantoin 0.2(wt)%, the balance for pure water.

[0020] The preparation method of the above-mentioned lysozyme is as follows: put corn flour, protein powder, beef jelly, and amino acids into a fermenter, add water to dissolve, sterilize, and cool; then inoculate and cultivate, culture conditions: temperature 37 ° C, stirring speed 600 rpm, tank pressure 0.03 MPa, pH cha...

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Abstract

The invention relates to a biological lysozyme compound preparation and a preparation method thereof. The preparation method comprises the following steps: dissolving lysozyme, amino acid, proteolytic enzyme, lysostaphin and peroxidase in water according to a certain proportion, transferring the mixed solution into a mixing tank, adding sorbitol, hydrated silica, aluminium hydroxide, glycerol, sodium lauroyl sarcosine, edible essence, cellulose gum, carrageenan, hydroxyethyl cellulose, sodium phytate, saccharin sodium, strontium chloride, trisodium phosphate, borneols, sodium borate, cinnabar, natrii sulfas exsiccatus and allantoin according to corresponding proportion, reacting for 47-49 h under a constant temperature condition of 38-42 DEG C to prepare the activated biological lysozyme compound preparation finished product. The biological lysozyme compound preparation belongs to a novel non-hormonic and non-antibiotic protein function preparation, has extremely great capacities of bacteriolyzing, reducing inflammation and enhancing immunity, and various effects of resisting various infections and promoting rehabilitation.

Description

technical field [0001] The invention relates to a bacteriostatic and bactericidal preparation, in particular to a biological lysozyme compound preparation and a preparation method thereof. Background technique [0002] The traditional treatment of inflammatory diseases such as oral diseases and chronic pharyngitis mainly uses antibiotics for bactericidal treatment, and antibiotics are only a bactericidal mechanism that inhibits the growth of bacterial cell walls without selection. After long-term use, bacteria will develop drug resistance and resistance. Drug properties, and then gradually reduce the efficacy, affect the therapeutic effect. [0003] It is a technical problem to be solved by those skilled in the art to develop non-antibiotic biological agents to improve the antibacterial and bactericidal effects and eliminate side effects as much as possible. The Chinese patent application number 2013105597688 discloses a compound lysozyme oral spray and its preparation meth...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/66A61Q11/00A61Q19/10A61P31/04
Inventor 徐志良童星
Owner JIANGSU XUE BAO DAILY CHEM CO
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