Garlic oil nanometer-scale microemulsion liquid and preparation method thereof

Abstract

The present invention relates to a garlic oil nanometer-scale microemulsion liquid and a preparation method thereof. The garlic oil nanometer-scale microemulsion liquid comprises the following components (in mass percentage): surfactant 6%-65%, auxiliary surfactant 2%-30%, garlic oil 2%-13%, vegetable oil 0%-80%, and water 0-85%. Furthermore, the present invention also relates to a garlic oil nanometer-scale microemulsion liquid preparation method which includes the following steps: at room temperature, the garlic oil and the vegetable oil are mixed into mixture oil phase, and then the surfactant and auxiliary surfactant are added and mixed, and mixed in a swirl manner by slowly stirring, water is added into the system under the slowing stirring condition until the mutation of viscosity, and thus the clear and transparent garlic oil nanometer-scale microemulsion liquid is obtained. The garlic oil nanometer-scale microemulsion liquid can be used in the fields of food, health-care food, medicines and cosmetic, and the application scope of the fat-soluble garlic oil is extended.

Description

Technical field [0001] The invention belongs to the technical field of food processing nanotechnology, and specifically relates to a nano-level microemulsion and a preparation method thereof, in particular to a garlic oil nano-level microemulsion and a preparation method thereof. Background technique [0002] Garlic has the reputation of "natural spectrum antibiotic". The garlic oil extracted from garlic contains more than 20 active components, including alliin, ajoene, adenosine, choline-like, etc. Garlic oil has health effects such as antibacterial, lowering blood pressure, lowering blood lipids, preventing and treating atherosclerosis, lowering blood sugar, anti-oxidation, anti-tumor, etc. It has a wide range of application value in food, health food, medicine, cosmetics and other fields. However, garlic oil itself is difficult to dissolve in water, has poor dispersibility in aqueous solutions, low bioavailability, and strong volatility, which greatly restricts its application...

AI Technical Summary

Problems solved by technology

[0005] CN1172598C discloses that garlic essential oil and sorbitol T80 are mixed with water under heating conditions and stirred and emulsified to make garlic essential oil sterilizing and insecticidal emulsion. The garlic essential oil prepared by this invention is an emulsion with large particle size, opaque and transparent , and is in a thermodynamically unstable state. If the emulsions are stored for a long time, coagulation will occur and the separation of the water phase and the oil phase will occur, which will affect the sensory properties in the actual application process.

CN1579375A adds allicin to auxiliary materials to make allicin fat emulsion, but in this process, it is necessary to use a high-pressure homogenizer to homogenize the emulsion, which consumes a lot of energy, and the product obtained is opaque white emulsion droplets, and the particle size is micron level. Delamination also occurs after prolonged storage

The allicin fat emulsion injection disclosed by CN101112360B is also stirred by a high-speed mixer, and then the garlic fat emulsion is obtained through a high-pressure homogenizer with high energy consumption. The average particle diameter of the prepared emulsion is relatively large, which is 200nm. unstable

CN102727727A discloses an oil-in-water type sodium nitrate and garlic oil nanoemulsion antihypertensive drug with an average particle size of 32.9nm. This invention only relates to the application of oil-in-water type garlic oil and drug mixed nanoemulsion in the field of medicine. There is no reference to the preparation of garlic oil water-in-oil microemulsion drugs