Catalytic synthesis method of n-butyl glycolate

Abstract

The invention belongs to the technical field of chemical synthesis, and concretely relates to a catalytic synthesis method of n-butyl hydroxyacetate. The method comprises the following steps: carrying out a refluxing dehydrating esterification reaction on glycolic acid and an excess amount of n-butanol under the catalysis of acidic ion exchange resin, filtering, and distilling to synthesize n-butyl hydroxyacetate, wherein the acidic ion exchange resin is preprocessed by a buffer solution. Processing of the acidic ion exchange resin by the buffer solution with a certain pH value greatly improves the synthesis yield and selectivity of n-butyl hydroxyacetate. The method has the advantages of low device requirements, no corrosion and few three wastes, and is especially suitable for amplified production.

Description

technical field

[0001] The invention belongs to the technical field of chemical synthesis, and in particular relates to a catalytic synthesis method of n-butyl glycolate. Background technique

[0002] With its unique molecular structure, n-butyl glycolate has functional groups such as ɑ-H, hydroxyl, and ester groups at the same time, making it have the chemical properties of alcohol and ester at the same time, and can undergo carbonylation reaction, oxidation reaction, hydrolysis reaction and ɑ- Substitution reactions, etc., become an important chemical raw material. It is easily soluble in nitrocellulose, cellulose acetate, and cellulose acetate propionate. At the same time, it is also an excellent solvent for many celluloses, resins, and rubbers. It can be used as a cleaning agent for semiconductors, an additive for cosmetics, and paints. Therefore, it is widely used in many fields such as chemical industry, medicine, pesticides, feed, dyes, and spices. The traditional s...