Check patentability & draft patents in minutes with Patsnap Eureka AI!

Preparation method of bioactive coatings on surfaces of titanium metals

A bioactive and bioactive glass technology, which is applied in the field of preparation of bioactive coatings on titanium metal surfaces, can solve the problems of low bonding strength of coatings, easy peeling off of coatings, planting failures, etc., so as to improve biological activity and bonding strength. High, guaranteed bonding strength effect

Active Publication Date: 2016-04-20
GUANGZHOU MEDICAL UNIV
View PDF7 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is now found that the surface bioactive coatings or films obtained by the above technologies have certain limitations, mainly due to the low bonding strength and poor stability of the coatings. When used for long-term cyclic dynamic stress, the coatings will not Still easy to fall off, causing planting failure

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of bioactive coatings on surfaces of titanium metals
  • Preparation method of bioactive coatings on surfaces of titanium metals
  • Preparation method of bioactive coatings on surfaces of titanium metals

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0020] Preparation of BG and HAP microparticles

[0021] Bioactive glass (BG) can be 45S5 bioglass or other bioglass, which can be prepared by sol-gel method (sol-gel), or can be prepared by high-temperature melting-quenching-crushing method, or directly purchase bioglass Micronized. The preparation method is introduced below by taking the preparation method of 45S5 glass high-temperature melting-quenching-crushing as an example.

[0022] Formula for preparing 45S5 bioglass: Na 2 O24.5wt%, CaO24.5wt%, P 2 o 5 6.0wt%, SiO 2 45% by weight. Mix the above-mentioned substances according to their components and contents, pour them into a crucible, melt them in a muffle furnace at about 1400°C, then pour them into distilled water for quenching and fragmentation, collect the fragmented bioglass, dry at 120°C, and agate Dry grind in a mortar until it passes through a 40-mesh sieve, and use absolute ethanol as a medium, agate as a ball stone, and grind the filtrate in a ball mill ...

Embodiment 1

[0025] 1. Coating of BG and HAP particles on the surface of titanium metal

[0026] First, use the above-mentioned BG particles of 100 mesh to 250 mesh as the sandblasting medium to carry out sandblasting treatment on the surface of titanium metal (the sandblasting treatment adopts BG particles, the sandblasting particle size is 100-250 mesh, and the sandblasting pressure is 5 -10bar, the sandblasting distance is 0.5-1cm, and the sandblasting time is 4-5min), and then ultrasonically cleaned with acetone and absolute ethanol, and dried for use to obtain titanium metal for sandblasting.

[0027] Take an appropriate amount of BG microparticles with a particle size of 50-500nm and put them into distilled water, absolute ethanol and glacial acetic acid, and disperse them ultrasonically to form 1.0g / LBG microparticle water suspension, 1.0g / LBG microparticle ethanol suspension, and 1.0g / LBG microparticle ethanol suspension. LBG Microparticles Acetic Acid Suspension. Take an appropri...

Embodiment 2

[0035] 1. Coating of BG and HAP particles on the surface of titanium metal

[0036] First, use the above-mentioned BG particles of 100 mesh to 250 mesh as the sandblasting medium to carry out sandblasting treatment on the surface of titanium metal (the sandblasting treatment adopts BG particles, the sandblasting particle size is 100-250 mesh, and the sandblasting pressure is 5 -10bar, the sandblasting distance is 0.5-1cm, and the sandblasting time is 4-5min), and then ultrasonically cleaned with acetone and absolute ethanol, and dried for use to obtain titanium metal for sandblasting.

[0037]Take an appropriate amount of BG microparticles with a particle size of 50-500nm and put them into distilled water, absolute ethanol and glacial acetic acid, and disperse them ultrasonically to form 1.0g / LBG microparticle water suspension, 1.0g / LBG microparticle ethanol suspension, and 1.0g / LBG microparticle ethanol suspension. LBG Microparticles Acetic Acid Suspension. Take an appropria...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method of bioactive coatings on surfaces of titanium metals. The preparation method comprises the following steps: coating the surfaces of the titanium metals by using calcium phosphate or bioactive glass particles, wherein the particle density of the particles per square centimeter is 0.4-0.6 cm(2); then solidifying the calcium phosphate or bioactive glass particles in TiO2 fusion oxide layers of titanium surfaces through micro-arc oxidation; and forming bioactive coatings on the surfaces of the titanium metals. Compared with a coating treated by pure micro-arc oxidation, the preparation method not only improves bioactivity of micro-arc oxidation layers of pure titanium surfaces, and meanwhile maintains bonding strength of the bioactive coatings. The bonding strength of the novel bioactive coatings is higher than that of coatings which are subjected to pure micro-arc oxidation and biological mineralization. Therefore, by the bioactive coatings formed on the surfaces of the titanium metals, the bonding strength of the micro-arc oxidation layers is guaranteed, bioactivity of the micro-arc oxidation coatings is improved further, and bioactive sites provide conditions for anchoring, attaching and multiplication of biological tissue cells.

Description

Technical field: [0001] The invention belongs to the field of medical devices, and in particular relates to a method for preparing a bioactive coating on the surface of titanium metal. Background technique: [0002] Due to their excellent biocompatibility and mechanical properties, titanium and titanium alloys have been widely used in medical implants, such as artificial joints, orthopedic internal fixation components, dental implants, and vascular stents. However, the binding ability of titanium and titanium alloys to bone and soft tissue is not satisfactory. Therefore, since the 1980s, dozens of surface modification technologies have been used to improve the surface bioactivity of titanium and titanium alloys. Such as plasma spraying method, electrochemical deposition method, sol-gel method, laser cladding method, laser cladding method, acid-base treatment method and micro-arc oxidation method, etc. However, it is now found that the surface bioactive coatings or films obt...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C25D11/26C25D15/00A61L27/32A61L27/06A61L27/30A61L31/02A61L31/08
CPCA61L27/06A61L27/306A61L27/32A61L31/022A61L31/082A61L31/086A61L2400/18A61L2420/02A61L2420/06A61L2430/02A61L2430/12C25D11/26C25D15/00
Inventor 陈晓明朱继翔阳范文田秀梅
Owner GUANGZHOU MEDICAL UNIV
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com