Streptococcus salivarius and its application in the preparation of drugs for removing halitosis

A technology of halitosis and medicine, applied in the field of microorganisms, to achieve the effect of wide application prospects and value
CN107058175BActive Publication Date: 2020-04-03ICDC CHINA CDC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ICDC CHINA CDC
Publication Date
2020-04-03

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Abstract

The invention provides an oral probiotic strain, the preservation number of which is CGMCC NO.12899, the preservation date is August 23, 2016, the preservation classification is named Streptococcus salivarius (Streptococcus Salivarius), and the preservation unit is China Microbiology The General Microbiology Center of the Culture Collection Management Committee is located at the Institute of Microbiology, Chinese Academy of Sciences, No. 3, Yard 1, Beichen West Road, Chaoyang District, Beijing. The bacterial strain can obviously inhibit the production of volatile sulfide of the bad breath standard strain Clostridium nucleatum. The invention also discloses the application of the above bacterial strains in the preparation of medicines for removing halitosis, which has broad application prospects and value in the preparation of microecological preparations for removing halitosis and constructing beneficial oral microecological environment effects.
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Description

technical field

[0001] The invention relates to a probiotic and its application, belonging to the field of microorganisms. Background technique

[0002] Bad breath, a symptom of a foul odor when breathing, is a common disease, with prevalence in Chinese ranging from 22% to more than 50%. Patients with bad breath do not dare to communicate with others in close proximity, resulting in inferiority complex and affecting normal interpersonal and emotional communication, which is very distressing. Bad breath is mainly caused by bacteria in the oral cavity, especially the volatile sulfide (Volatile Sulphur Compound, VSC) produced by the fermentation of Gram-negative anaerobic bacteria accumulated in the posterior 1 / 3 of the tongue. Studies have shown that VSCs are mainly produced by bacteria such as Porphyromonas gingivalis, Stenabacter forsythia, Prevotella intermedia and Fusobacterium nucleatum. Kazor et al. used PCR to analyze the bacteria in the oral cavity of healthy and hal...

Claims

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