A kind of 2-aminobenzimidazole bactericidal microsphere and its synthesis method and application

Abstract

The invention discloses a 2-aminobenzimidazole sterilization microsphere, and a synthetic method and application thereof. The synthetic method comprises the following steps: (1), a chloromethylated bead is used as a parent compound, 2-aminobenzimidazole is used as a ligand, a catalyst of metal sodium is added, and under the protection of nitrogen gas, stirring is performed for 10-12h at a rotation speed of 200rpm at a temperature of 70-90 DEG C, washing is finished, and vacuum drying is performed at a temperature of 50 DEG C; and (2), the material obtained in the step (1) is placed in a reaction vessel, propylene oxide is added under the atmosphere of nitrogen gas, stirring is performed for 5-7h at a temperature of 15-25 DEG C, benzyl chloride is added to the reaction vessel, reaction is performed for 5-7h at room temperature with stirring, then filtration is performed, and washing is repeatedly performed by using ethanol and distilled water in a filtration process, and the filtered microsphere is subjected to vacuum drying at a temperature of 50 DEG C, so that the water-insoluble immobilized sterilization microsphere is obtained. The raw material of the obtained sterilization microsphere is the chloromethylated bead, and the chloromethylated bead has relatively high mechanical strength and physical stability, the source is wide, the price is low, and the economic benefits are remarkable. The synthetic method of the composite sterilization microsphere provided in the invention is convenient in operation, green and economic, and has good application prospect.

Description

technical field [0001] The invention belongs to the field of bactericides, and in particular relates to 2-aminobenzimidazole bactericidal microspheres and a synthesis method and application thereof. Background technique [0002] In recent years, the pollution of fresh water resources has been serious, and the safety problems of canned water and liquid food have occurred frequently. Commonly used indicator bacteria or other indicator microorganisms in drinking water are: total coliforms, fecal coliforms, faecal streptococci, coli phages, enteroviruses, Staphylococcus, Bifidobacterium, Clostridium perfringens , Salmonella, aeruginosa, Pseudomonas, Shigella, Vibrio parahaemolyticus, etc. 80% of human diseases come from polluted water. According to the World Health Organization's survey results, 500,000 people die each year due to drinking unhealthy water, and the direct or indirect losses have exceeded 1% of GDP in that year. The pollution of pathogenic microorganisms not onl...

AI Technical Summary

Problems solved by technology

However, traditional fungicides also have insurmountable shortcomings: when the content of organic matter in the water source is slightly high, oxidative fungicides such as chlorine gas sterilization will produce chlorinated organic matter, which can cause cancer; poor stability, easy to decompose, high transportation and storage costs, and Potential threats such as explosion; in industrial water treatment, the stripping and washing effect on bacterial scale and slime is poor

Because water-soluble fungicides will cause certain hazards in residual water and liquid food after use, oxidizing fungicides will produce toxic by-products, and non-oxidizing fungicides are residual toxicity problems, and there is a risk of "secondary pollution"

Images