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Soluble freckle removing micro-needle

A soluble and micro-needle technology, applied in the field of soluble freckle-removing micro-needles, can solve problems such as unstable curative effect, long curing time, easy mildew or oxidation, etc., to expand the safety range and application range, reduce dosage and side effects, avoid The effect of gastrointestinal digestion and absorption

Inactive Publication Date: 2018-01-12
陈彦彪
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] Various depigmenting agents, the most commonly used is hydroquinone (hydroquinone), which has always been the first choice for topical treatment of chloasma. prone to this complication
The curative effect of other topical drug treatments on Asians is relatively unstable, and it is prone to adverse consequences such as dermatitis, skin atrophy, and aggravation of pigmentation
[0014] The above various freckle removal methods have no obvious therapeutic effect, long healing time and high recurrence rate
So far, there is no method or medicine that can fundamentally remove stains.
[0015] In addition, most of the freckle removal products currently on the market are transported and stored in the form of liquid. The liquid storage time is short, which is not conducive to transportation, and is prone to mildew or oxidation.

Method used

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  • Soluble freckle removing micro-needle

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0061] The preparation method of the above-mentioned soluble freckle-removing microneedle mainly includes the following steps:

[0062] S1: Preparation of Scutellaria baicalensis extract, Scutellaria japonica extract, peppermint extract, Cowslip extract, Cottonwort leaf extract, Medicinal herba baicalensis extract, Lemon balm leaf extract, Yarrow extract and Duyun Maojian tea extract, set aside.

[0063] S2: Weigh the scutellaria baicalensis extract obtained in step S1, the eucalyptus extract, the peppermint extract, the Cowslip extract, the Cottonwort leaf extract, the medicinal Popona extract, and the Bee flower leaf extract, yarrow extract and Duyun Maojian tea extract are added to 300-400 parts of deionized water, mixed and stirred evenly, and filtered to obtain the filtrate.

[0064] S3: Weigh tranexamic acid, urea, citric acid, soluble collagen, xanthan gum, hexapeptide-2, nonapeptide-1, caprylyl salicylic acid, sodium hydroxide, mandelic acid, 1,2- Hexylene glycol and...

Embodiment 1

[0070] This embodiment provides a soluble freckle-removing microneedle. In parts by weight, the active ingredients include: 1.5 parts of tranexamic acid, 3 parts of urea, 0.2 parts of citric acid, 10 parts of soluble collagen, 40 parts of xanthan gum, and hexapeptide-216 56 parts of nonapeptide-1, 14 parts of Scutellaria baicalensis extract, 18 parts of Eucalyptus extract, 7 parts of peppermint extract, 16 parts of Cowslip extract, 0.5 part of Cottongrass leaf extract, medicinal mother-in-law 0.5 parts sodium extract, 15 parts lemon balm flower leaf extract, 53 parts yarrow extract, 7 parts caprylyl salicylic acid, 0.2 parts sodium hydroxide, 50 parts mandelic acid, 1,2-hexanediol 3 part, 1 part of caprylyl glycol.

[0071] The preparation method of the above-mentioned soluble freckle-removing microneedle comprises the following steps:

[0072] S1: Preparation of Scutellaria baicalensis extract, Scutellaria japonica extract, peppermint extract, Cowslip extract, Cottonwort lea...

Embodiment 2

[0079]This embodiment provides a soluble freckle-removing microneedle. In parts by weight, the active ingredients include: 32 parts of tranexamic acid, 10 parts of urea, 1.5 parts of citric acid, 33 parts of soluble collagen, 15 parts of xanthan gum, and hexapeptide-216 , 8 parts of nonapeptide-1, 2 parts of Scutellaria baicalensis extract, 5 parts of Eucalyptus extract, 30 parts of peppermint extract, 43 parts of Cowslip extract, 5 parts of Cottongrass leaf extract, medicinal mother-in-law 0.5 parts of sodium extract, 36 parts of lemon balm leaf extract, 13 parts of yarrow extract, 8 parts of Duyun Maojian tea extract, 30 parts of caprylyl salicylic acid, 1.8 parts of sodium hydroxide, 75 parts of mandelic acid , 8 parts of 1,2-hexanediol, 3 parts of caprylyl glycol.

[0080] The preparation method of the above-mentioned soluble freckle-removing microneedle comprises the following steps:

[0081] S1: Preparation of Scutellaria baicalensis extract, Scutellaria japonica extrac...

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Abstract

The invention discloses a soluble freckle removing micro-needle. The soluble freckle removing micro-needle is prepared from the following active ingredients according to weight: tranexamic acid, urine, citric acid, soluble collagen, xanthan gum, argireline-2, nonapeptide-1, scutellaria galericulata extract, malva flower extract, mentha piperita leaf extract, primula veris extract, alchemilla japonica leaf extract, veronica officinalis extract, melissa officinalis leaf extract and achillea millefolium extract. The soluble freckle removing micro-needle provided by the invention has the followingadvantages that various freckle removing medicaments are highly selected and are optimally combined, so that the dosage and the toxic or side effect of each medicament are reduced, and the safety range and the application range of the soluble freckle removing micro-needle are expanded; the metabolism of skin can be improved, and microenvironment around the skin can be improved, so that freckles are moved fundamentally and do not reoccur; moreover, the soluble freckle removing micro-needle is easy to produce, transport and store, and the cost is reduced.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a soluble freckle-removing microneedle. Background technique [0002] Spots are spots that are different in color from their surroundings. Including freckles, dark spots, chloasma and age spots, etc., which belong to pigmented disordered skin diseases. It is a common skin disease with brown or hyperpigmentation and disfigurement on the face due to the increase of skin melanin. It mainly occurs on the cheeks and forehead, and is aggravated after sun exposure. It is more common in women and is related to pregnancy and long-term menstrual disorders. The treatment of pigmentation is very difficult, and the common prevention and treatment methods include general preventive measures and drug treatment. Drug therapy includes systemic drug therapy and local drug therapy. Specifically, there are the following methods. [0003] 1. General precautions [0004] (1) Avoid s...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/44A61K8/42A61K8/365A61K8/65A61K8/64A61K8/73A61K8/02A61Q19/02
Inventor 陈彦彪唐骢
Owner 陈彦彪
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