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External hydrogel material for skin

A hydrogel and skin technology, applied in the field of biomedicine, can solve the problems of insignificant effect, underutilization of marine resources, single application field of gel materials, etc. The effect of increasing the effect

Inactive Publication Date: 2018-06-22
王子昂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the current hydrogel materials still have a limited range of raw materials, the application of gel materials is single, and marine resources are not fully utilized; the moisturizing effect is general, and there is no clear research on skin moisturizing properties; the antiseptic and antibacterial components are single, and the effect is not good. obvious technical issues

Method used

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  • External hydrogel material for skin
  • External hydrogel material for skin
  • External hydrogel material for skin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Embodiment one, the chemical composition analysis of Ligustrum lucidum gum

[0067] Ligustrum lucidum has the functions of nourishing the liver and kidney, improving eyesight and black hair. It is mainly used for vertigo and tinnitus, soreness of waist and knees, premature graying of beard and hair, and blurred vision. Modern medical research believes that Ligustrum lucidum can inhibit Helicobacter pylori for the treatment of stomach diseases, and also has the effect of inhibiting abnormal metabolism of purine, and can be used for the treatment of gout and hyperuricemia. Modern pharmacological research has also found that it has the effect of lowering blood fat and blood sugar. There are currently no reports on privet gum. In the present invention, the privet gum is extracted for the first time, and its main chemical components are characterized.

[0068] The preparation method of Ligustrum lucidum gum is as follows: According to the weight ratio of Ligustrum lucidum...

Embodiment 2

[0085] Embodiment two, the preparation of external skin hydrogel

[0086] A hydrogel for external skin application and a preparation method thereof.

[0087] 1. Preparation of sodium alginate

[0088] A method for extracting sodium alginate from light dried kelp, the steps are as follows:

[0089] Take the whole lightly dried kelp, wash it with deionized water to remove the surface sediment, dry it naturally, and chop it up. Take 60g of the above-mentioned kelp, place it in 1L of 0.1mol / L dilute hydrochloric acid, and soak it at room temperature for 10h. Deionized water to wash away the surface extracts, appropriate amount of 3% Na 2 CO 3 Soak in the solution for 3 minutes, remove the kelp epidermis, wash it with deionized water and place it in a 2L flask. Add 420mL 2% Na 2 CO 3 solution, kept stirring in a water bath at 40°C for 2 hours, the stirring speed was 400rpm / min, the extract was in the form of a paste, added 180mL deionized water to dilute the extract, continu...

Embodiment 3

[0108] Embodiment 3, skin moisturizing effect test of external skin hydrogel material

[0109] 1. Test raw materials:

[0110] (1) embodiment and comparative example prescription are as follows:

[0111] Example 3-A, the hydrogel contains 2% sodium alginate, 2% Ligustrum lucidum gum, 2% modified acrylic polymer, and 5% propylene glycol aqueous solution in weight percent.

[0112] Example 3-B, the hydrogel contains 5% sodium alginate, 0.5% privet gum, 0.5% modified acrylic polymer, and 2% propylene glycol aqueous solution in weight percent.

[0113] Example 3-C, the hydrogel contains 2% sodium alginate, 1% Ligustrum lucidum gum, 4% modified acrylic polymer, and 8% propylene glycol aqueous solution as a weight percentage.

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Abstract

Blue sea not only contains rich resources, but also has huge economic benefits. Natural and environment-friendly external hydrogel which is used for skin and has good moisturizing and antibacterial efficacy is prepared from polymerization products from raw materials including alginate extracted from marine algae, seed gum extracted from plant seeds, chitin extracted from marine shrimps and crabs,acrylic acid and the like as well as a compound antibacterial agent. The hydrogel material is prepared from, in percentage by weight, 0.5%-5% of sodium alginate, 0.5%-8% of glossy privet fruit gum, 0.5%-5% of a modified acrylic acid polymer, 75.5%-99.5% of a propylene glycol water solution and 0.01%-2% of the compound antibacterial agent, wherein the volume fraction of the propylene glycol water solution is 2%-15%. The moisturizing characteristics of sodium alginate, glossy privet fruit gum and the modified acrylic acid polymer are researched, and compared with sodium alginate, glossy privet fruit gum and the modified acrylic acid polymer used alone, the gel composition has notably improved moisturizing effect; the compound antibacterial agent replaces a conventional antiseptic and antibacterial compound and is used for corrosion prevention of gel, and safe and efficient bacteriostasis of the hydrogel material is realized.

Description

technical field [0001] The invention belongs to the field of biomedicine, in particular to a hydrogel material for skin external application. Background technique [0002] The blue ocean not only contains rich resources, but also has huge economic benefits. How to make full use of marine resources to develop diverse biological materials has important research value. [0003] Biomedicine is one of the key industries in the country. Due to its green, environment-friendly, and resource-saving characteristics, biomaterials are gradually becoming another new leading industry leading technological innovation and economic development in the contemporary world. The preparation of biomaterials with multiple functions and their application in the field of medicine and health is a current research hotspot. Hydrogels prepared from bio-based water-soluble polymers have been widely used in the field of biomedicine, such as tissue filling materials, cartilage materials, drug coatings and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L5/04C08L5/00C08L33/02C08L5/08C08K5/053C08K5/13C08F220/06C08F220/18C08F220/56A61K8/02A61K8/04A61K8/73A61K8/81A61K8/92A61L26/00A61Q17/00A61Q19/00
CPCA61K8/0212A61K8/042A61K8/73A61K8/733A61K8/736A61K8/8147A61K8/922A61L26/0023A61L26/0066A61L26/008A61Q17/005A61Q19/00C08F220/06C08L5/00C08L5/04C08L33/02C08L2205/035C08L5/08C08K5/053C08K5/13C08F220/18C08F220/56
Inventor 王子昂
Owner 王子昂
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