Preparation method of hydroxyethyl chitosan nano composite bone support material
A hydroxyethyl chitosan and nanocomposite technology, applied in the field of biomedical materials, can solve problems such as poor mechanical properties, and achieve the effects of low cost, good adhesion, and good biological activity
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0024] (1) Preparation of biphasic calcium phosphate nanopowder: 0.4M Ca(NO 3 ) 2 .4H 2 O solution and 0.2M (NH 4 ) 2 HPO 4 The solution was added into a three-necked flask according to the calcium-phosphorus molar ratio of 1.65:1, stirred and mixed evenly, and then the pH was adjusted to 11 with 25% ammonia water to obtain a white powder precipitate. After filtering, the white powder was washed with deionized water. Then dry it at 80°C, put it into a muffle furnace for roasting, first raise the temperature to 1125°C at a rate of 10°C / min, keep it for 1 hour, then drop it to room temperature with the furnace, then take it out and grind it, and finally pass it through a 200-mesh sieve to obtain a two-phase Calcium phosphate nanopowder;
[0025] (2) prepare hydroxyethyl chitosan: get 10g chitosan and join in the 50wt% sodium hydroxide solution of 16.7g and carry out alkalization, obtain chitosan solution, described alkalization is carried out in-20 ℃ refrigerator, The alka...
Embodiment 2
[0029] The preparation process is basically the same as in Example 1, except that the mass ratio of hydroxyethyl chitosan, cellulose, and biphasic calcium phosphate nanopowder in step (2) is 2:1:1.
[0030] The scanning electron micrograph of the composite bone scaffold material that embodiment 2 makes is shown in figure 1 ,in, figure 1 A is the composite bone scaffold material of embodiment 1, figure 1 B is the composite bone scaffold material of Example 2.
Embodiment 3
[0032] The preparation process is basically the same as in Example 1, except that the mass ratio of hydroxyethyl chitosan, cellulose, and biphasic calcium phosphate nanopowder in step (2) is 1:1:2.
[0033] The scanning electron micrograph of the composite bone scaffold material that embodiment 3 makes is shown in figure 1 ,in, figure 1 A is the composite bone scaffold material of embodiment 1, figure 1 B is the composite bone scaffold material of embodiment 2, figure 1 C is the composite bone scaffold material of Example 3.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com