Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method and application of biomedical degradable magnesium alloy surface fine grain composite layer

A biomedical and magnesium alloy technology, applied in metal processing equipment, coatings, medical science, etc., to achieve uniform corrosion, improve mechanical properties, and improve interface reactions

Inactive Publication Date: 2018-09-28
CHINA WEAPON SCI ACADEMY NINGBO BRANCH
View PDF8 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are no literatures or patents at home and abroad to propose the preparation method and application of nano-hydroxyapatite-fine-grain composite layer on the surface of such biomedical degradable magnesium alloys.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0033] A method for preparing a fine-grain composite layer on the surface of a biomedical degradable magnesium alloy, the specific steps are as follows:

[0034] 1) Substrate treatment: select the cast, extruded or rolled magnesium alloy substrate, process the magnesium alloy substrate to the required size, and use sandpaper with a roughness of 400#, 800#, 1200#, 2000# to sand the deposition surface in turn Grinding is performed to remove the oxide layer on the deposition surface. Then use acetone and absolute ethanol to clean the polished substrate in turn, rinse with distilled water, and dry with cold air;

[0035] 2) Powder preparation: put nano-hydroxyapatite powder with a particle size of 60-200nm into the powder feeder of cold spray equipment;

[0036] 3) Substrate fixation: Install the substrate on the cold spray equipment workbench and place it under the cold spray gun; you can choose to keep the spray gun stationary and the workbench move; or to complete the spraying i...

Embodiment 1

[0040] In this embodiment, the nano-hydroxyapatite powder with a particle size of 60-80nm is selected, and the particle shape is spherical; the CS-2000 type cold spray system is used to prepare the coating, the pressure is 2Mpa, the moving speed of the spray gun is 50mm / s, and the spraying distance is 10mm, the working gas is nitrogen, and a dense nano-hydroxyapatite coating is deposited on the surface of the cast magnesium-copper alloy; then a friction stirring head with a shaft shoulder diameter of 16mm, a stirring needle diameter of 6mm, and a length of 5mm is selected, and the tool speed is 400r / min. The processing speed is 100mm / min, so that a layer of fine-grained, uniform and dense nano-hydroxyapatite-fine-grain composite structure is formed on the surface of extruded pure magnesium. The coating thickness is about 200-250μm, and the grain size is about 50-100μm.

[0041] The material has good biocompatibility, and the cytotoxicity rating is grade 1. The degradation rate...

Embodiment 2

[0043] In this embodiment, the nano-hydroxyapatite powder with a particle size of 100-120nm is selected, and the particle shape is spherical; the CS-2000 type cold spray system is used to prepare the coating, the pressure is 4Mpa, the spray gun moving speed is 100mm / s, and the spraying distance is 20mm, the working gas is nitrogen, and a dense nano-hydroxyapatite coating is deposited on the surface of the extruded magnesium-strontium alloy; then a friction stirring head with a shaft shoulder diameter of 16mm, a stirring needle diameter of 6mm, and a length of 5mm is selected, and the tool speed is 1000r / min , the processing speed is 150mm / min, so that a layer of nano-hydroxyapatite-fine-grain composite structure with fine grains, uniform and dense structure is formed on the surface of extruded pure magnesium, the coating thickness is about 50-100μm, and the grain size About 20-50 μm.

[0044] The material has good biocompatibility, and the cytotoxicity rating is 0. The degrada...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Granularityaaaaaaaaaa
Granularityaaaaaaaaaa
Thicknessaaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method and application of a biomedical degradable magnesium alloy surface fine grain composite layer. The method comprises the steps that a magnesium alloy substrate is subjected to grinding treatment and chemical cleaning; nanometer hydroxyapatite powder is sprayed to the surface of the magnesium alloy substrate in a cold spray mode, and a nanometer hydroxyapatite coating is obtained; and the surface of the magnesium alloy substrate with the nanometer hydroxyapatite coating is subjected to friction stirring machining, and a nanometer hydroxyapatite-fine grain composite structure is formed on the surface of the magnesium alloy. The method is based on a high-efficiency rapid cold spray coating preparation technique and friction stirring machining technique, a nanometer hydroxyapatite-fine grain composite structure layer is prepared on the surface of the magnesium alloy, the method has the advantages of being reasonable in process, low in cost, highin efficiency, environmentally friendly and the like, the corrosion resistance of the biomedical degradable magnesium alloy can be effectively improved, the excellent cellular affinity and osteogenesis function are achieved, the biomedical function of osteoblasts can regulated, the osseointegration capacity is improved, and the method has broad application prospects in the medical fields such as orthopedic implantation.

Description

technical field [0001] The invention belongs to the technical field of surface modification, and in particular relates to a preparation method and application of a fine-grain composite layer on the surface of a biomedical degradable magnesium alloy. Background technique [0002] As a new biodegradable medical metal material, magnesium alloy has become a research hotspot in the field of biomaterials in recent years. Biodegradable magnesium alloy materials cleverly use the characteristics of magnesium alloys that are prone to corrosion and degradation in the human environment to achieve the medical clinical purpose of metal implants being absorbed, consumed or excreted by the human body with tissue healing in the body, thereby avoiding secondary damage. The pain and financial burden of surgery on patients. Magnesium alloys have biomechanical properties similar to those of human bone, and their density and elastic modulus are close to those of human cortical bone. It can reali...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): B23P15/00C23C24/04B23K20/12A61L27/04A61L27/32A61L27/50A61L27/54
Inventor 刘辰徐永东朱秀荣任政庞松王军邵志文
Owner CHINA WEAPON SCI ACADEMY NINGBO BRANCH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com